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Pharmacology and toxicology

247 posts
  • This content is machine translated Schizophrenia

Desirable and undesirable effects of antipsychotics.

Continuous and effective pharmacotherapy is essential for patients with schizophrenia, as they are at high risk for developing a severe mental illness. But what constitutes successful medication therapy management? This…
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  • 5 min
  • This content is machine translated Psychotropic drugs with high dependence potential

Inadequate prescribing practices come with far-reaching implications

A retrospective UK study analyzed the additional healthcare costs attributable to inadequate prescribing practices. As data from Switzerland show, among other things, the prescription prevalence of benzodiazepines in patients in…
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  • 2 min
  • This content is machine translated Obesity

Sustainable weight reduction with the help of new therapy options

Eat less, move more – obese patients know these recommendations well. However, the implementation is anything but simple. And even if weight loss does occur, the dreaded rebound effect undoes…
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  • 5 min
  • This content is machine translated Infectious diseases: useful information for the general practitioner

Containing antibiotic resistance – prescribing antibiotics wisely

Antibiotics are a very important pillar of modern medicine for the purpose of prophylaxis and control of bacterial infections. But used too often or over too long a period of…
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  • 9 min
  • This content is machine translated Drug interactions

What the family doctor needs to know

Patients would make the title of this post more authoritative: Do my physicians safely protect me from avoidable risks due to inappropriate combination of drugs? This illustrates the standard to…
CME-Test
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  • 3 min
  • This content is machine translated Depression

Antidepressants: relapse prophylaxis for sustained therapeutic success

For moderate to severe depressive episodes, the efficacy of treatment with antidepressants is considered proven. Remission-stabilizing maintenance therapy is an important aspect to reduce the risk of relapse. As a relapse…
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  • 3 min
  • This content is machine translated Special extract of peppermint and caraway oil

Phytopreparation inhibits intestinal motility and promotes secretion

An in vitro study on human digestive tissue published in 2021 demonstrated secretion-promoting effects in addition to the muscle-relaxing effects observed in previous studies. In addition, the scientists found that…
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  • 27 min
  • This content is machine translated Schizophrenia

Partial D2 dopamine agonists: pharmacology and clinical significance.

Schizophrenia is characterized, among other things, by dopaminergic dysregulation. All antipsychotics approved for their treatment are antagonists of dopamine receptors, particularly D2 and D3 receptors. The three partial D2 dopamine…
CME-Test
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  • 4 min
  • This content is machine translated SARS-CoV-2

Pelargonium sidoides shows antiviral and immunomodulatory effects in vitro.

Currently available treatment options against Covid-19 are very limited and research for effective drugs is feverish. An international team of scientists recently published results of a preclinical in vitro study indicating…
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  • 3 min
  • This content is machine translated ART: "single tablet" regimen with triple combination.

Compelling “real world” data in HIV patients over 65 years of age.

There are increasing numbers of older people living with HIV, but the 65+ age group is generally underrepresented in clinical trials. An ongoing study in a “real world” setting is…
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  • 3 min
  • This content is machine translated Heart failure

HFrEF – the four pillars of modern pharmacotherapy

Chronic heart failure is one of the leading causes of death and reasons for hospitalization in developed countries. The prognosis is often poor – within five years, about half of…

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