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Pharmacology and toxicology

373 posts
  • This content is machine translated Rosacea - multifaceted and multifactorial

Topical and systemic active ingredients: proven and new therapeutic approaches

Several risk factors and triggers are known to contribute to the different clinical manifestations of rosacea by activating or modulating neurovascular or immunological processes. Thanks to advances in research into...…
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  • 6 min
  • This content is machine translated From diagnostics to personalized therapy

Nuclear medical imaging for Parkinson’s disease

Nuclear medicine imaging enables early objectification of dopaminergic deficits and supports differential diagnosis. Imaging findings help with therapy planning, follow-up and individualization of treatment. Nuclear medicine procedures are a crucial...…
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  • 7 min
  • This content is machine translated Psoriasis in difficult localizations: Nail psoriasis

IL-23 and IL-17 as a target – selected study findings

Although nail psoriasis remains a challenge, considerable progress has been made in both diagnostic and therapeutic terms. This is reflected, for example, in current analyses of the GUIDE and ZODIPSO...…
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  • 4 min
  • This content is machine translated Neuropathies - CIDP

Differentiate chronic inflammatory demyelinating polyneuropathy (CIDP)

CIDP can only be reliably differentiated from clinical mimics through systematic diagnostics. Diagnostic findings guide the selection of suitable immunotherapy. Chronic inflammatory demyelinating polyneuropathy shows diverse phenotypes and is often...…
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  • 5 min
  • This content is machine translated Seborrheic dermatitis in adults

Do not underestimate the symptom burden

Seborrhoeic eczema is caused by a complex interplay of dysbiosis, impaired skin barrier function and immunological dysregulation. It occurs preferentially in areas rich in sebaceous glands and is associated with...…
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  • 9 min
  • This content is machine translated Irritable Bowel Syndrome

“Best practice” recommendations for step-by-step clarification and stage-adapted therapy

The diagnosis of irritable bowel syndrome (IBS) is based on the Rome IV criteria for functional gastrointestinal disorders. The main symptoms are abdominal pain and altered bowel habits, but patients...…
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  • 5 min
  • This content is machine translated Nutritional supplements and cognition

5-HTP: The serotonin booster for cognition in old age

Can a dietary supplement measurably improve cognitive ageing processes? When 5-HTP is useful – and when caution is needed due to interactions. A randomized study shows: 5-HTP increases serotonin levels,...…
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  • 6 min
  • This content is machine translated Subsyndromal anxiety disorders: Family doctor as first point of contact

Practical recommendations for diagnostics and therapy

A consensus paper published in 2025 provides pragmatic advice on the diagnosis and treatment of subsyndromal anxiety disorder (SSA). If it has been established that the patient has SSA, it...…
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  • 4 min
  • This content is machine translated Case Report

17-year-old patient with acne fulminans

In the present case, a complex interplay between inflammatory and infectious processes was found. The close temporal relationship between the dose increase of isotretinoin and the onset of symptoms suggests...…
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  • 11 min
  • This content is machine translated From statins to metformin

Preventive pharmacology and longevity

In medicine, “longevity” is now less anti-ageing marketing than a very specific question of precision prevention: which pharmacological interventions prevent (or delay) cardiometabolic, renal, oncological and functional endpoints – and...…
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  • 6 min
  • This content is machine translated Pediatric epilepsy

Diazepam nasal spray for infants

Fast and socially uncomplicated treatment of seizure clusters in infants. Intranasal diazepam shows reliable drug absorption and good tolerability. A phase 1/2a study in 2- to 5-year-old epilepsy patients confirms...…

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