This content is machine translated Oncolytic virus in stage II melanoma Innovative method for predicting therapy response Until now, it was assumed that TVEC works by activating T cells. However, in a study by British and US scientists published in JCO Oncology Advances, the T cell populations...…
View Post 3 min This content is machine translated Phimosis and penile cancer under SGLT2i Increased risk for men with T2D In recent years, sodium-glucose cotransporter 2 inhibitors (SGLT2i) have been widely used in the treatment of type 2 diabetes, as they not only provide improved glycemic control, but also offer...…
View Post 12 min This content is machine translated Diabetic ketoacidosis Recommendations for action in practice Diabetic ketoacidosis (DKA) is an acutely life-threatening complication of diabetes mellitus that occurs predominantly in type 1 diabetes, but is also increasingly occurring in people with type 2 diabetes. A...… CME-Test
View Post 6 min This content is machine translated Migraine: better quality of life thanks to multimodal care Broader selection of innovative migraine prophylactics and acute therapies The fact that migraine therapy is changing is also reflected in the recent publication of the updated S1 guideline “Treatment of migraine attacks and prophylaxis of migraine”. Although triptans are...…
View Post 4 min This content is machine translated Therapy of non-tumor-related pain Do not prescribe opioids lightly for musculoskeletal pain A UK research team used electronic primary care patient records from 2006-2021 based on the Clinical Research Practice Datalink (CPRD) to identify opioid prescriptions. The analyses revealed that almost three...…
View Post 3 min This content is machine translated Migraine Fremanezumab for comorbid migraine and depression Migraine and depression often reinforce each other and make treatment more difficult. The UNITE study shows that the CGRP antibody fremanezumab significantly reduces both migraine days and depressive symptoms –...…
View Post 6 min This content is machine translated Case study Moyamoya disease in a 23-year-old female patient Moyamoya disease is characterized by progressive narrowing of the internal carotid arteries and their branches. This can lead to ischemic and/or hemorrhagic disorders of the cerebral circulation. According to the...…
View Post 6 min This content is machine translated Dapagliflozin for T2D and heart failure Epicardial fat reduced in patients with type 2 diabetes and HF The co-occurrence of heart failure (HF) and diabetes leads to a higher risk of complications, higher mortality and worse outcomes than either disease alone. Studies have shown the importance of...…
View Post 10 min This content is machine translated A hub of biological aging Mitochondrial dysfunction and energy metabolism Mitochondrial dysfunction is not defined as an isolated “ATP problem” in the Hallmarks of Ageing framework, but as a systemic shift in bioenergetics, redox signaling, quality control and immune metabolism....…
View Post 3 min This content is machine translated Health Literacy Promoting health literacy: from the abstract to the concrete level The Federal Council’s health policy strategy “Health 2030” sets out a framework for action in health policy aimed at securing healthcare provision in the coming years. The second of the...…
View Post 8 min This content is machine translated Pharmacological therapy Anxiety symptoms in eating disorders Eating disorders are mental illnesses that are strongly influenced by biological, psychological and social stress factors. Anxiety symptoms are among the most common and most impairing accompanying symptoms. The systematic...…
