This content is machine translated Ozanimod for relapsing-remitting multiple sclerosis Signs of improved tolerability with prolonged treatment Ozanimod, a selective modulator of sphingosine-1-phosphate (S1P) receptors 1 and 5, has demonstrated efficacy in relapsing-remitting multiple sclerosis (RMS) in Phase 2 and 3 studies. At a dose of 0.92...…
View Post 8 min This content is machine translated When basal cell carcinomas prove difficult to treat Reaching the goal with innovative therapy strategies The further development of patient-oriented, function-preserving treatment strategies is an important concern of skin cancer research. For patients with advanced cutaneous basal cell carcinoma (BCC), there is a need for...…
View Post 5 min This content is machine translated Irritable Bowel Syndrome IBS or endometriosis? Chronic pelvic pain ( CPP) is a common reason for referral to gynecology departments and is commonly attributed to endometriosis. However, gastrointestinal disorders, particularly irritable bowel syndrome (IBS), have several...…
View Post 6 min This content is machine translated Type 2 diabetes: sarcopenia and frailty How can the breakdown of skeletal muscles be stopped? Insulin resistance, dyslipidemia, lack of exercise, inflammation and hypertension are among the most common risk factors for sarcopenia. Along with a loss of muscle mass and function, the risk of...…
View Post 4 min This content is machine translated Cholangiocarcinoma Modern molecular diagnostics and targeted therapy options Cholangiocarcinoma (CCA) is one of the most aggressive tumors of the hepatobiliary system and is often only diagnosed at an advanced stage. Advances in molecular diagnostics and targeted therapy are...…
View Post 6 min This content is machine translated Treatment resistant depression Esketamine nasal spray as monotherapy? New for treatment-resistant depression Despite a variety of approved antidepressant treatments, major depressive disorder (MDD) remains one of the leading causes of disability worldwide and has been shown to shorten the life expectancy of...…
View Post 6 min This content is machine translated Analysis of SNVCS data from the period 2005-2022 TBE vaccination for children and adolescents in Switzerland The Swiss National Vaccination Study (SNVCS) is a nationwide cross-sectional study that evaluates the vaccination rate of children and adolescents aged 2, 8 and 16 years. In a combined cross-sectional...…
View Post 4 min This content is machine translated Tuberculosis Detecting diabetes in TB patients early and efficiently People with diabetes have a significantly increased risk of tuberculosis and poorer treatment outcomes, which is why systematic diabetes screening is recommended for TB patients. A meta-analysis showed that previously...…
View Post 4 min This content is machine translated Trichophyton indotineae Terbinafine-resistant dermatophytoses are on the rise in Central Europe Trichophyton indotineae (T. indotineae) often causes persistent, recurrent skin infections and is spreading worldwide. The fact that the number of cases has also increased in Central Europe in recent years...…
View Post 11 min This content is machine translated Peristomal skin health Focus on preventive care options For people with a stoma, peristomal skin health is a key factor for quality of life. With an incidence of up to over 70%, skin complications in the stoma area...… CME-Test
View Post 7 min This content is machine translated Disease-modifying therapies for ATTR-CM TTR stabilizers, gene silencing and gene scissors: where do we stand? Advances in the understanding of the pathophysiology of transthyretin amyloid cardiomyopathy (ATTR-CM) have revolutionized the therapeutic landscape in recent years. TTR stabilizers such as tafamidis and acoramidis can reduce TTR...…
