This content is machine translated Behçet's disease Apremilast approved for the treatment of oral aphthae Behçet’s disease is a rare, chronic, multisystemic inflammatory disease that causes vasculitis. Oral aphthae occur in more than 97% of affected individuals and are associated with significant impairment of quality…
View Post 3 min This content is machine translated Cancer medicine of the future Car-T cell therapy and its application in practice CAR-T cell technology is considered the latest achievement in cancer medicine. The first approvals in Europe took place in mid-2018 – Switzerland followed at the end of 2018. Currently, the…
View Post 4 min This content is machine translated SGLT-2 inhibitors Dapagliflozin now also available for non-diabetics for the treatment of heart failure (HFrEF) Based on the results of the DAPA-HF study, Swissmedic has approved dapagliflozin for the treatment of heart failure with reduced ejection fraction (HFrEF), whether or not patients have type 2…
View Post 4 min This content is machine translated Guselkumab Study success: application for admission to PsoA submitted New Phase III data from the DISCOVER-1 and DISCOVER-2 studies show improvement in joint and skin symptoms of psoriatic arthritis at week 52, and an indication expansion of guselkumab is…
View Post 5 min This content is machine translated Non-resectable BRAF-mutated melanoma Update COLUMBUS study: BRAF/MEK inhibition has long-lasting effect For almost two years, an effective therapeutic option has been available for patients with non-resectable or metastatic BRAFV600-mutated melanoma with the combination of encorafenib plus binimetinib. An analysis of the…
View Post 2 min This content is machine translated VERTIS-CV Study Evidence base of SGLT-2 inhibitors supplemented by further piece of the mosaic Ertugliflozin as an add-on to standard treatment was shown to be non-inferior to placebo in terms of MACE (major adverse cardiac event) in this large-scale international study. This confirmed the…
View Post 5 min This content is machine translated Therapy of overactive bladder Minimize side effect risks and increase compliance Anticholinergics are among the standard pharmacological therapies for overactive bladder. It is important to choose the right preparation for each patient. The side effect risks vary considerably in some cases.…
View Post 2 min This content is machine translated Influenza virus A and B Do not miss flu vaccination During the current COVID-19 pandemic, inpatient health care services could be severely strained as the number of cases increases. Flu vaccination can help reduce the burden of illness in winter…
View Post 3 min This content is machine translated Valerian and lemon balm extract Herbal preparation alleviates subsyndromal ADHD symptoms in school children In an empirical study, positive effects of high-dose combination treatment were demonstrated in elementary school students who did not fully meet the criteria for an ADHD diagnosis but who nevertheless…
View Post 4 min This content is machine translated Non-resectable melanoma New triple therapy improves progression-free survival Both protein kinase inhibitors and ipilimumab/nivolumab combined have better efficacy than their respective monotherapies in patients with non-resectable melanoma. This has been known for some time. An interesting new approach…
View Post 5 min This content is machine translated Epigastric pain Bio-psycho-social approach to the therapy of functional abdominal pain Functional abdominal pain can lead to a significant impairment of the quality of life and daily coping of the affected person and can already occur in adolescence. Chronification is common…