Medizinonline Medizinonline
  • News
    • News
    • Market & Medicine
  • Patients
    • Disease patterns
    • Diagnostics
    • Therapy
  • Partner Content
    • Dermatology
      • Atopic dermatitis and psoriasis news
      • Dermatology News
    • Diabetes
      • Dia-Month Club – Type 2 Diabetes
      • Diabetes in Motion
      • Diabetes Podcasts
    • Gastroenterology
      • IBD matters
      • Forum Gastroenterology
      • Ozanimod: ulcerative colitis
      • Reflux Update
    • Immunology
      • Primary immunodeficiency – exchange of experience
    • Vaccinate
      • Herpes zoster
    • Infektiologie
    • Neurology
      • EXPERT ULTRASONIC: Introduction to ultrasound-guided injection
      • MS News
      • MS Therapy in Transition
    • Oncology
      • Swiss Oncology in motion
    • Orthopedics
      • Osteoporosis in motion
    • Phytotherapie
    • Practice Management
      • Aargau Cantonal Bank
      • Claraspital
    • Psychiatry
      • Geriatric Psychiatry
    • Rheumatology
  • Departments
    • Allergology and clinical immunology
    • General Internal Medicine
    • Anesthesiology
    • Angiology
    • Surgery
    • Dermatology and venereology
    • Endocrinology and Diabetology
    • Nutrition
    • Gastroenterology and Hepatology
    • Genetics
    • Geriatrics
    • Gynecology
    • Hematology
    • Infectiology
    • Cardiology
    • Nephrology
    • Neurology
    • Emergency and intensive care medicine
    • Nuclear Medicine
    • Oncology
    • Ophthalmology
    • ORL
    • Orthopedics
    • Pediatrics
    • Pharmacology and toxicology
    • Pharmaceutical medicine
    • Phlebology
    • Physical medicine and rehabilitation
    • Pneumology
    • Prevention and health care
    • Psychiatry and psychotherapy
    • Radiology
    • Forensic Medicine
    • Rheumatology
    • Sports Medicine
    • Traumatology and trauma surgery
    • Tropical and travel medicine
    • Urology
    • Dentistry
  • CME & Congresses
    • CME continuing education
    • Congress Reports
    • Congress calendar
  • Practice
    • Noctimed
    • Practice Management
    • Jobs
    • Interviews
  • Log In
  • Register
  • My account
  • Contact
  • English
    • Deutsch
    • Français
    • Italiano
    • Português
    • Español
  • Publications
  • Contact
  • Deutsch
  • English
  • Français
  • Italiano
  • Português
  • Español
Subscribe
Medizinonline Medizinonline
Medizinonline Medizinonline
  • News
    • News
    • Market & Medicine
  • Patienten
    • Krankheitsbilder
    • Diagnostik
    • Therapie
  • Partner Content
    • Dermatology
      • Atopic dermatitis and psoriasis news
      • Dermatology News
    • Diabetes
      • Dia-Month Club – Type 2 Diabetes
      • Diabetes in Motion
      • Diabetes Podcasts
    • Gastroenterology
      • IBD matters
      • Forum Gastroenterology
      • Ozanimod: ulcerative colitis
      • Reflux Update
    • Immunology
      • Primary immunodeficiency – exchange of experience
    • Vaccinate
      • Herpes zoster
    • Infektiologie
    • Neurology
      • EXPERT ULTRASONIC: Introduction to ultrasound-guided injection
      • MS News
      • MS Therapy in Transition
    • Oncology
      • Swiss Oncology in motion
    • Orthopedics
      • Osteoporosis in motion
    • Phytotherapie
    • Practice Management
      • Aargau Cantonal Bank
      • Claraspital
    • Psychiatry
      • Geriatric Psychiatry
    • Rheumatology
  • Departments
    • Fachbereiche 1-13
      • Allergology and clinical immunology
      • General Internal Medicine
      • Anesthesiology
      • Angiology
      • Surgery
      • Dermatology and venereology
      • Endocrinology and Diabetology
      • Nutrition
      • Gastroenterology and Hepatology
      • Genetics
      • Geriatrics
      • Gynecology
      • Hematology
    • Fachbereiche 14-26
      • Infectiology
      • Cardiology
      • Nephrology
      • Neurology
      • Emergency and intensive care medicine
      • Nuclear Medicine
      • Oncology
      • Ophthalmology
      • ORL
      • Orthopedics
      • Pediatrics
      • Pharmacology and toxicology
      • Pharmaceutical medicine
    • Fachbereiche 26-38
      • Phlebology
      • Physical medicine and rehabilitation
      • Phytotherapy
      • Pneumology
      • Prevention and health care
      • Psychiatry and psychotherapy
      • Radiology
      • Forensic Medicine
      • Rheumatology
      • Sports Medicine
      • Traumatology and trauma surgery
      • Tropical and travel medicine
      • Urology
      • Dentistry
  • CME & Congresses
    • CME continuing education
    • Congress Reports
    • Congress calendar
  • Practice
    • Noctimed
    • Practice Management
    • Jobs
    • Interviews
Login

Sie haben noch keinen Account? Registrieren

  • Remarkable casuistry

More than one meningioma?

    • News
    • Oncology
    • RX
  • 2 minute read

A case presentation impressively demonstrated that other tumors can metastasize within a meningioma. So you have to look closely at what it is when you come across a meningioma.

(ag) An astonishing case was recently presented in the Journal of Clinical Endocrinology & Metabolism [1]: A 60-year-old woman with progressive, iodine-refractory thyroid carcinoma with skeletal and pulmonary metastases developed right-sided ataxia. Intracranial metastasis was suspected. Scintigraphy after the sixth run of I-131(radioiodine) therapy had identified a new lesion of the posterior cranial fossa. Magnetic resonance imaging of the brain showed a dura-resident mass over 20 mm in diameter in the posterior fossa, suggestive of meningioma.

With a tentative diagnosis of metastasis to the posterior fossa, treatment changed from prednisolone to dexamethasone 4 mg twice daily. This medication was maintained until metastasectomy one month later.

Histopathology revealed a WHO grade I meningioma. Interestingly, this meningioma contained a metastatic, poorly differentiated thyroid carcinoma. Although the patient had a symptomatic response to metastasectomy and external beam radiotherapy, she died a year later from complications of cauda equina syndrome.

A tumor within a tumor

Undiagnosed thyroid cancer may present as intracranial metastases mimicking meningioma [2]. Thus, it is important to more closely examine a lesion that appears benign at first glance. Meningioma is the most common intracranial tumor that harbors metastases (often from the lung and breast) [3].

Thyroid cancer and meningiomas are similar in biological, metabolic, molecular, and hormonal factors. However, the exact mechanism behind tumor-to-tumor metastases is unknown. Meningiomas themselves (without thyroid cancer) may show iodine affinity on scintigraphy due to edema and high vascularity.

What is the finding?

The authors note that this is the first published case of poorly differentiated thyroid carcinoma metastasizing inside an intracranial meningioma that developed from a multifocal mixed thyroid cancer.

Although meningiomas can physiologically concentrate I-131, their case, according to the authors, shows that the exclusion of metastases from a potentially more dangerous primary tumor in an apparently benign lesion is of great importance.

Literature:

  1. Ling M, et al: Tumor within Another Tumor: An Unusual Case of Metastatic Poorly Differentiated Thyroid Carcinoma within an Intracranial Meningioma. J Clin Endocrinol Metab 2014, doi: 10.1210/jc.2014-1310.
  2. Portocarrero-Ortiz L, et al: Thyroid follicular carcinoma presenting as skull and dural metastasis mimicking a meningioma: a case report. J Neurooncol 2009; 95: 281-284.
  3. Moody P, et al: Tumor to tumor metastasis: pathology and neuroimaging considerations. J Clin Exp Pathol 2012; 5(4): 367-373.

InFo Oncology & Hematology 2014; 2(7): 3-4.

Autoren
  • Andreas Grossmann
Publikation
  • InFo ONKOLOGIE & HÄMATOLOGIE
Related Topics
  • Casuistry
  • Meningioma
  • Metastasis
  • Thyroid gland
  • Tumor
Previous Article
  • Prostate Cancer

PSA screening still controversial

  • News
  • Oncology
  • RX
  • Urology
View Post
Next Article
  • Risk factors for prostate cancer

First gonorrhea, then cancer

  • News
  • Oncology
  • RX
  • Urology
View Post
You May Also Like
View Post
  • 12 min
  • Liver steatosis with metabolic dysfunction

New nomenclature for non-alcoholic fatty liver disease

    • CME continuing education
    • Gastroenterology and Hepatology
    • General Internal Medicine
    • RX
    • Studies
View Post
  • 15 min
  • Diabetes mellitus

Treatment of comorbidities in older people

    • Cardiology
    • CME continuing education
    • Endocrinology and Diabetology
    • General Internal Medicine
    • Geriatrics
    • RX
View Post
  • 4 min
  • Type 2 diabetes: PAD and diabetic foot syndrome

Prevention is better than cure – don’t miss the risk foot

    • Cardiology
    • Congress Reports
    • Endocrinology and Diabetology
    • General Internal Medicine
    • Geriatrics
    • Prevention and health care
    • RX
View Post
  • 2 min
  • Prostate cancer

High-resolution ultrasound could diagnose prostate cancer faster

    • Congress Reports
    • Oncology
    • RX
    • Studies
    • Urology
View Post
  • 9 min
  • Chronic lung diseases

Sarcopenia and malnutrition in the context of pneumological rehabilitation

    • CME continuing education
    • General Internal Medicine
    • Geriatrics
    • Nutrition
    • Pneumology
    • RX
    • Sports Medicine
    • Studies
View Post
  • 8 min
  • Psychooncology

Communication as the key to therapy adherence

    • CME continuing education
    • General Internal Medicine
    • Practice Management
    • RX
View Post
  • 16 min
  • Blastic plasmacytoid dendritic cell neoplasia

Rare malignancy from a dermatological perspective

    • CME continuing education
    • Dermatology and venereology
    • Genetics
    • Hematology
    • Oncology
    • RX
View Post
  • 4 min
  • From symptom to diagnosis

Lung carcinoma – Pancoast tumor

    • Cases
    • Education
    • Oncology
    • Pneumology
    • Radiology
    • RX
    • Surgery
Top Partner Content
  • Forum Gastroenterology

    Zum Thema
  • Herpes zoster

    Zum Thema
  • Dermatology News

    Zum Thema
Top CME content
  • 1
    Treatment of comorbidities in older people
  • 2
    New nomenclature for non-alcoholic fatty liver disease
  • 3
    Rare malignancy from a dermatological perspective
  • 4
    Communication as the key to therapy adherence
  • 5
    Patience, knowledge and persistence in therapy

Newsletter

Sign up and stay up to date

Subscribe
Medizinonline
  • Contact
  • General terms and conditions
  • Imprint

Input your search keywords and press Enter.