Parkinson’s is one of the most common neurodegenerative diseases and continues to pose major challenges for neurology. It has long been clear that age is the decisive risk factor – but the mechanisms of how biological ageing and neuronal degeneration interact have so far been incompletely understood. In recent years, a cellular process has increasingly become the focus of research: senescence. It describes a state of irreversible cell cycle arrest, accompanied by profound metabolic changes and a pro-inflammatory secretion profile.
Autoren
- Tanja Schliebe
Publikation
- InFo NEUROLOGIE & PSYCHIATRIE
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