This content is machine translated Systemic mastocytosis Diagnostics and drug therapy approaches – an update A KIT mutation analysis from the bone marrow is recommended in the case of highly elevated tryptase levels. In particular, adults often have a point mutation in codon 816 of…
View Post 8 min This content is machine translated Psoriasis The era of biologics – a tour d’horizon through significant research decades The development of highly effective biologics was preceded by research efforts over several decades. Advances in immunopathogenetic and molecular genetic analyses contributed significantly to the generation of these innovative system…
View Post 10 min This content is machine translated Disease of the subcutaneous adipose tissue Lipedema – a painful fatty tissue disease of the extremities in women. Lipedema is a painful, disproportionate increase in fat in women; on legs and arms, as well as hips and buttocks. Lipedema has been officially classified as a disease in the… CME-Test
View Post 3 min This content is machine translated Rare diseases Current diagnostic criteria for neurofibromatosis type 1 – an update. Also known as “von Recklinghausen disease,” neurofibromatosis type 1 is a rare genetic multi-organ disease. A common feature of neurofibromatosis type 1 that can be diagnosed early in its course…
View Post 2 min This content is machine translated Atopic dermatitis in childhood and adolescence Dupilumab proves itself in daily practice In the “BioDay Registry” study, treatment with dupilumab in pediatric patients with atopic dermatitis in a “real world” setting resulted in significant improvement in disease severity and associated symptoms. Tolerability…
View Post 8 min This content is machine translated Ichthyoses Broad spectrum of genetic cornification disorders Ichthyoses comprise a heterogeneous group of rare hereditary skin disorders whose classification can prove difficult. Accordingly, rapid diagnosis and therapy initiation is a challenge in everyday clinical practice. Experts specialized…
View Post 6 min This content is machine translated Clarification of contact eczema Important and common allergens – an up-to-date overview Frequently, chronic contact dermatitis is a combination of irritant and contact allergic eczema. The selection of the test allergens is anamnesis-guided. In addition to nickel – still the most common… CME-Test
View Post 3 min This content is machine translated Cutaneous T-cell lymphoma (CTCL) First targeted antibody approved for CTCL patients with MF or SS The approval of the anti-CCR4 antibody mogamulizumab provides patients with cutaneous T-cell lymphoma (CTCL) of the mycosis fungoides (MF) and Sézary syndrome (SS) subtypes with an effective non-chemotherapeutic intervention for…
View Post 7 min This content is machine translated Pediatric corner Cutaneous manifestations of Lyme disease: case series. Lyme disease is the most common tick-borne infectious disease in Europe. If Lyme disease is detected early, it can be treated well with antibiotics. A typical early-stage skin condition is…
View Post 2 min This content is machine translated Onychomycoses: cohort study. Comparison of molecular diagnostic and conventional methods An international research team involving the University Hospitals of Lausanne and Zurich has compared different diagnostic methods in a large-scale retrospective study. In agreement with previous empirical findings, the conclusion…
View Post 6 min This content is machine translated Atopic dermatitis Skin microbiome normalizes under tralokinumab therapy Atopic dermatitis is associated with dysbiosis of the cutaneous microbiome. Characteristic is reduced bacterial diversity, with Staphylococcus aureus often being the dominant bacterial genus. In a recent study, it was…
