This content is machine translated Nutritional supplements and cognition 5-HTP: The serotonin booster for cognition in old age Can a dietary supplement measurably improve cognitive ageing processes? When 5-HTP is useful – and when caution is needed due to interactions. A randomized study shows: 5-HTP increases serotonin levels,...…
View Post 5 min This content is machine translated Friedreich's ataxia Interim analyses of the PROFA study show “Unmet needs” The PROFA study focuses, among other things, on patient-reported psychosocial effects of Friedreich’s ataxia (FRDA) at different stages of the disease. The study comprises a cohort of FRDA patients in...…
View Post 4 min This content is machine translated Study report Sphingolipid profile in early-stage primary biliary cholangitis Using ultra-high performance liquid chromatography coupled with tandem mass spectrometry (UHPLC-MS/MS), a Polish research team discovered interesting new insights into the changes in sphingolipid metabolism in patients with early-stage primary...…
View Post 6 min This content is machine translated Angiosarcoma of the heart A diagnostic and therapeutic “black box” Primary angiosarcomas of the heart are among the rarest and most aggressive malignant tumors. The unspecific symptoms, rapid progression and complex differential diagnosis make early detection considerably more difficult. Despite...…
View Post 5 min This content is machine translated Ataxias Friedreich’s ataxia: when the energy metabolism attacks the nervous system Energy deficiency instead of pure oxidative stress: New data show that in Friedreich’s ataxia, disturbances in fatty acid and ketone body metabolism in particular contribute to selective neurodegeneration. The article...…
View Post 3 min This content is machine translated Risk of osteoporosis in autoimmune liver diseases Always determine bone density in PBC, PSC and AIH Studies show that primary biliary cholangitis (PBC), primary sclerosing cholangitis (PSC) and autoimmune hepatitis (AIH) are associated with a significantly increased risk of developing osteopenia or osteoporosis. For this reason,...…
View Post 3 min This content is machine translated Neuroendocrine tumors Precision medicine in diagnostics and therapy Thanks to modern imaging and molecular characterization, neuroendocrine tumours can now be detected and classified in a much more targeted manner. New therapeutic procedures such as radioligand therapy and targeted...…
View Post 3 min This content is machine translated Case report: Complication after type 2 diabetes Topical corticosteroids lead to ketoacidosis Hyperglycemic crises due to topical corticosteroid use are extremely rare. In this case report, however, physicians were faced with an unusual case of diabetic ketoacidosis (DKA) triggered by the postoperative...…
View Post 12 min This content is machine translated NSCLC Bispecific antibodies for rare EGFR mutations Rare EGFR mutations such as exon 20 insertion changes have long been considered a therapeutic dead end in non-small cell lung cancer (NSCLC). Current data show that innovative mechanisms of...…
View Post 6 min This content is machine translated Subsyndromal anxiety disorders: Family doctor as first point of contact Practical recommendations for diagnostics and therapy A consensus paper published in 2025 provides pragmatic advice on the diagnosis and treatment of subsyndromal anxiety disorder (SSA). If it has been established that the patient has SSA, it...…
View Post 12 min This content is machine translated Patient-centered rounds in medicine Aligning care with the patient Patient-centered, patient-centered medicine respects and integrates individual preferences, values, or needs and has grown in importance in patient care in recent years. In clinical care, it is therefore important that...… CME-Test