This content is machine translated Chronic hand eczema Topical pan-JAK-i vs. systemic retinoid: head-to-head study Alitretinoin is currently the only systemic treatment approved for severe chronic hand eczema when patients do not respond adequately to topical corticosteroids. The topical pan-Janus kinase (JAK) inhibitor delgocitinib is...…
View Post 6 min This content is machine translated Study report Long-term data on CFTR modulators in children with cystic fibrosis Cystic fibrosis (CF) is one of the most common congenital metabolic diseases in Europe. The treatment options for CF patients have expanded significantly in recent years. CFTR modulators improve the...…
View Post 5 min This content is machine translated Multiple sclerosis Multiple sclerosis 2025: New strategies against progression and the role of microglia The treatment of multiple sclerosis has made enormous progress thanks to highly effective disease-modifying therapies, in particular anti-CD20 antibodies. For most newly diagnosed patients, a life without disability is realistic....…
View Post 8 min This content is machine translated A syndrome between decompensation and chronification Worsening Heart Failure The deterioration of chronic heart failure – so-called worsening heart failure (WHF) – is no longer solely an acute event, but an expression of complex, often repetitive pathophysiological dynamics. Despite...…
View Post 6 min This content is machine translated Actinic keratosis Field-directed therapy methods: what the European guideline recommends Topically applied medications are a cornerstone of the field-directed treatment of actinic keratoses. In photodynamic therapy, a topical agent is combined with a procedural method. In cases of insufficient response,...…
View Post 4 min Education Geriatrics Neurology Pharmacology and toxicology RX Studies Opicapon: double benefit for motor function and sleep in Parkinson’s disease Sleep disorders are among the most common non-motor Parkinson’s symptoms. The targeted treatment of sleep disorders is an important part of Parkinson’s therapy and can significantly improve quality of life....…
View Post 6 min This content is machine translated Itching in primary biliary cholangitis When the skin becomes agony The agonizing itching is one of the most difficult symptoms to bear in patients with primary biliary cholangitis (PBC). It can have a far greater impact on everyday life, sleep...…
View Post 3 min This content is machine translated Case report: Hiccups after ketoacidosis Nebulized lidocaine brings relief Persistent hiccups are a rare but distressing symptom that can significantly affect the quality of life of patients with diabetic ketoacidosis (DKA). In one clinical case, treatment with inhaled nebulized...…
View Post 8 min This content is machine translated Cardiogenic shock - 2025 update Between standardization, team processes and targeted cycle support Cardiogenic shock (CS) is and remains the most dramatic form of acute circulatory failure in cardiology. Despite decades of intensive research, hospital mortality has long remained in the range of...…
View Post 5 min This content is machine translated Multiple sclerosis Avoiding the nocebo trap with natalizumab biosimilars Monoclonal antibodies such as natalizumab are indispensable for multiple sclerosis therapy. A first recently approved biosimilar is clinically equivalent, as studies have shown. Nevertheless, reservations are widespread in practice. Patients...…
View Post 6 min This content is machine translated COPD and comorbidities Exacerbation frequency is associated with cardiopulmonary disease burden Exacerbation severity and frequency are crucial for the prognosis of COPD, but also appear to have a major impact on the course of comorbidities. There is a growing body of...…
