This content is machine translated Atopic Dermatitis in Children and Adults Topically Applied “Small Molecules”: Janus Kinases or PDE-4 as Targets? Intracellular target structures have gained importance as therapeutic targets for small-molecule therapeutics in atopic dermatitis (AD), and topical formulation ensures a localized pharmacological effect, thereby promoting a favorable safety profile...…
View Post 4 min This content is machine translated Dermatomyositis Glucocorticoids for more than one year Beyond its typical muscular and skin manifestations, dermatomyositis (DM), as a chronic systemic autoimmune myopathy, can cause serious systemic complications. Pulmonary and cardiac involvement, including interstitial lung disease and myocarditis,...…
View Post 4 min This content is machine translated From symptom to diagnosis Pulmonology – Lobus venae acygos The acygos vein is the thoracic continuation of the ascending lumbar veins cranial to the diaphragm and runs paravertebrally to the right of the thoracic vertebral bodies. With a prevalence...…
View Post 9 min This content is machine translated Atopic Dermatitis: Precisely Targeting Immunological Targets Interleukin blockade or OX40-(L) inhibition? The pathogenesis of atopic dermatitis (AD) involves a complex cascade that occurs at various levels. Immunomodulatory antibody therapies have been developed for the treatment of moderate-to-severe AD; these therapies interfere...…
View Post 8 min This content is machine translated Obesity: More than half of those affected have fatty liver disease From screening to multimodal intervention with GLP-1-RA or resmetirom Metabolic dysfunction-associated steatotic liver disease ( MASLD) is one of the most common complications of obesity and diabetes. If fatty liver disease is not addressed through lifestyle changes and, if...…
View Post 4 min This content is machine translated Preclinical Study on a Special Ginkgo biloba Extract What role do proanthocyanidins play? In a laboratory study published in 2025, proanthocyanidins (PACs) were isolated from the specialized ginkgo extract EGb 761® and evaluated using in vitro and in vivo assays in combination with...…
View Post 13 min This content is machine translated Two years of controlled data, two suppression strategies, and the risks associated with discontinuation Uterus myomatosus and heavy menstrual bleeding: oral GnRH antagonists Uterine fibroids are the most common tumors of the female reproductive organs, but only about one-quarter of affected women develop symptoms that require treatment. The most common symptoms are heavy...…
View Post 9 min This content is machine translated What the StepUp study changes and what has long been included in the guidelines Bacterial Vaginosis: Treatment for Partners and Prevention of Recurrence Acute treatment for bacterial vaginosis has been established for decades and is reliably effective. The clinical problem begins afterward. A large proportion of women experience a recurrence within a few...…
View Post 10 min This content is machine translated From a 10-Year Risk to a 3-Year Risk Bone Health After Menopause and During Endocrine Therapy The figures for Switzerland are well known, yet they are still underestimated: One in two women and one in five men suffer a fragility fracture after the age of 50....…
View Post 10 min This content is machine translated Exclusion Test sFlt-1/PlGF in Preeclampsia Diagnostics: What the Ratio Can Do The sFlt-1/PlGF ratio provides a very good answer to one question and only a partial answer to a second. It can rule out developing preeclampsia with a high degree of...…
View Post 7 min This content is machine translated Interview “On par with the gold standards for trauma” Stress-related disorders, chronic pain, and mental health comorbidities are encountered daily in the clinical practice of many medical specialties. Psychological interventions are increasingly recognized as an important component of multidisciplinary...…
