This content is machine translated Prostate Cancer Intracrine and Metabolic Tumor Adaptation Under Androgen Deprivation Androgen deprivation therapy (ADT) remains a cornerstone of prostate cancer treatment. It slows tumor growth but also triggers complex intracellular and metabolic response pathways. These tumor adaptations, which significantly influence...…
View Post 10 min This content is machine translated Alopecia areata in children, adolescents, and adults New Guideline Classifies the Evidence Base for Topical and Systemic Therapies The severity of alopecia areata has significant implications for counseling and treatment planning; however, to ensure the best possible care, the patient’s age, the individual impact of hair loss, and...…
View Post 12 min This content is machine translated Baxdrostat – a new class of drugs for treating difficult-to-control hypertension First Aldosterone Synthase Inhibitor Is Here It is the first new class of antihypertensive drugs in years: On May 18, 2026, the U.S. Food and Drug Administration (FDA) approved Baxdrostat (Baxfendy) as the first and only...…
View Post 3 min This content is machine translated Geriatric Small-Cell Lung Cancer Therapeutic Challenges Small-cell lung cancer remains one of the most aggressive types of cancer, particularly among older adults. New molecular insights and modern therapies offer new possibilities, but require careful consideration of...…
View Post 8 min This content is machine translated Chronic Pruritus in Renal, Hepatic, and Biliary Tract Diseases Pooled Expertise for Targeted Evaluation and Treatment According to the International Forum for the Study of Itch (IFSI), chronic pruritus can be classified into three categories. The etiological classification of pruritus on primarily non-lesional (IFSI II) skin...…
View Post 6 min This content is machine translated Chronic Tinnitus An exploratory study examined the effects of a specialized Ginkgo biloba extract In a study population aged 21–82 years, a 24-week treatment with the specialized ginkgo extract EGb 761® resulted in significant improvements in tinnitus-related parameters overall. Subgroup analyses revealed that those...…
View Post 6 min This content is machine translated Advanced Thyroid Cancer Molecular Mechanisms and New Therapeutic Approaches Thyroid carcinomas exhibit remarkable biological heterogeneity, which is increasingly shaping modern diagnosis and treatment. Molecular markers and innovative treatment approaches are fundamentally changing our understanding of pathogenesis, prognosis, and clinical...…
View Post 4 min This content is machine translated Epidermolysis bullosa Promoting Wound Healing with Gene Therapies and Birch Bark Extract Epidermolysis bullosa (EB) requires an interdisciplinary management approach tailored to the diagnosed EB subtype. Recently, new therapeutic approaches have been approved to improve symptomatic treatment. While a gel formulation containing...…
View Post 11 min This content is machine translated Cardiometabolism Retatrutid and the TRIUMPH Program: The Triple Agonist on the Horizon Incretin-based obesity therapy has advanced rapidly in just a few years: from GLP-1 receptor agonists (semaglutide) to the dual GIP/GLP-1 agonist tirzepatide and on to a triple agonist. Retatrutide (LY3437943)...…
View Post 7 min This content is machine translated Pediatric Retinoblastoma The Tumor Microenvironment and Modern Eye-Sparing Therapies Retinoblastoma is considered the prototypical pediatric tumor, whose biology is closely linked to the development of immature retinal tissue. New molecular and immunological findings show that the tumor microenvironment is...…
View Post 3 min This content is machine translated Adherence and management in asthma and COPD Better to listen to the pharmacist Pharmaceutical care has become an important part of the management of asthma and chronic obstructive pulmonary disease (COPD). There is evidence for its role in improving adherence, optimizing pharmacotherapy and...…