This content is machine translated Focus on new therapeutic targets and senolytics Cellular senescence Cellular senescence is considered a key biological program that can exert both protective and potentially pathogenic effects in tissues across the lifespan. If senescent cells persist, they are associated with...…
View Post 7 min This content is machine translated Arterial elasticity, vascular ageing, endothelial function Longevity and cardiovascular health 2025 Vascular ageing is not a purely “biological” concept, but can be measured clinically – via arterial stiffness (e.g. PWV), endothelial function (e.g. FMD) and the resulting risk profiles. In parallel...…
View Post 5 min This content is machine translated Bladder infections and urinary tract infections Survey reveals information deficits in the population A recently published survey conducted on the initiative of the European Association of Urology revealed worrying gaps in knowledge and misunderstandings regarding the prevention and treatment of cystitis and urinary...…
View Post 6 min This content is machine translated Hormone balance and longevity Ageing is not a substitution diagnosis In the longevity debate, “hormone balance” is often used as a synonym for “biologically younger”. Clinically, the term is only meaningful if it is linked to clearly defined axial disorders,...…
View Post 4 min This content is machine translated From symptom to diagnosis Abdominal pain – Colitis Chronic inflammatory bowel diseases are characterized by an intermittent course. In Crohn’s disease, the main sites of manifestation are the terminal ileum and the colon, while ulcerative colitis exclusively affects...…
View Post 9 min This content is machine translated Pathophysiology, cardiovascular consequences and metabolic interventions Obesity accelerates cardiovascular ageing Obesity and demographic ageing are two global megatrends that overlap in a particularly unfavorable way in the cardiovascular system. Both factors independently increase the risk of cardiovascular disease, but also...…
View Post 3 min This content is machine translated Casuistry Hernia turns out to be a 25 cm long Meckel’s diverticulum Meckel’s diverticulum is one of the most common congenital anomalies of the gastrointestinal system with an estimated prevalence of about 2% in the general population. Although it often remains asymptomatic,...…
View Post 7 min This content is machine translated Chronic inflammation as a driver of ageing Immunosenescence and inflammaging Immunosenescence and inflammaging are now regarded as central biological mechanisms of ageing. The age-related altered immune system is both weakened and chronically activated – with consequences for susceptibility to infection,...…
View Post 5 min This content is machine translated Side effects under opioid therapy Is it possible to avoid the inevitable? Opioid analgesics are an essential tool for the relief of cancer-related pain. However, in addition to their undeniable therapeutic value, opioids are associated with a number of predictable side effects...…
View Post 3 min This content is machine translated From symptom to diagnosis Dyspnea – pulmonary hamartomas Benign tumors of the lung can be epithelial, mesenchymal or embryonal in nature. Hamartomas are among the most common benign lung tumors. As they are usually asymptomatic, they are mostly...…
View Post 4 min This content is machine translated Phobia Propranolol and spider phobia: the time window is crucial A new study on spider phobia shows that propranolol only works in the long term if those affected re-encounter the fear-inducing stimulus early on. This brings reconsolidation into sharper focus...…
