This content is machine translated Neuroprotection, resilience and cognitive health in old age Longevity & Brain Cognitive health in old age is not an inevitable fate, but can be influenced to a relevant extent by modifiable factors. The Lancet Commission 2024 concludes that a significant proportion...…
View Post 5 min This content is machine translated Oncolytic virus in stage II melanoma Innovative method for predicting therapy response Until now, it was assumed that TVEC works by activating T cells. However, in a study by British and US scientists published in JCO Oncology Advances, the T cell populations...…
View Post 6 min This content is machine translated Case study Moyamoya disease in a 23-year-old female patient Moyamoya disease is characterized by progressive narrowing of the internal carotid arteries and their branches. This can lead to ischemic and/or hemorrhagic disorders of the cerebral circulation. According to the...…
View Post 7 min This content is machine translated Between hope and evidence gaps Tinnitus and phytotherapy Tinnitus is a highly prevalent symptom with a considerable impact on quality of life; randomized studies have not yet shown any clearly effective standard pharmacological therapy. Guidelines primarily recommend educational,...…
View Post 6 min This content is machine translated Oncology Study updates from the ESMO Congress The variety of topics presented at the congress of the European Society for Medical Oncology (ESMO) last October underlined the breadth of the field and the close interlinking of disciplines....…
View Post 6 min This content is machine translated Dapagliflozin for T2D and heart failure Epicardial fat reduced in patients with type 2 diabetes and HF The co-occurrence of heart failure (HF) and diabetes leads to a higher risk of complications, higher mortality and worse outcomes than either disease alone. Studies have shown the importance of...…
View Post 10 min This content is machine translated A hub of biological aging Mitochondrial dysfunction and energy metabolism Mitochondrial dysfunction is not defined as an isolated “ATP problem” in the Hallmarks of Ageing framework, but as a systemic shift in bioenergetics, redox signaling, quality control and immune metabolism....…
View Post 4 min This content is machine translated Study report Sphingolipid profile in early-stage primary biliary cholangitis Using ultra-high performance liquid chromatography coupled with tandem mass spectrometry (UHPLC-MS/MS), a Polish research team discovered interesting new insights into the changes in sphingolipid metabolism in patients with early-stage primary...…
View Post 8 min This content is machine translated Pharmacological therapy Anxiety symptoms in eating disorders Eating disorders are mental illnesses that are strongly influenced by biological, psychological and social stress factors. Anxiety symptoms are among the most common and most impairing accompanying symptoms. The systematic...…
View Post 4 min This content is machine translated Case study Wiedemann-Steiner syndrome in a 2-year-old girl The patient, who had a phenotype characterized by hypertelorism, thick eyebrows and other features, was found to have a c.517C>T nonsense mutation in the KMT2A gene. This rare heterozygous mutation...…
View Post 4 min This content is machine translated Psoriatic arthritis Long-term remission also possible without DMARDs Remission without disease-modifying antirheumatic drugs has become an ambitious goal in inflammatory rheumatic diseases. While it has been extensively studied in rheumatoid arthritis, its feasibility in psoriatic arthritis (PsA) has...…
