This content is machine translated Tumors of the Calcaneus Diagnostic Challenges of Rare Heel Tumors Tumors of the calcaneus are rare but diagnostically challenging. Nonspecific symptoms often lead to a delayed diagnosis. Diagnostic imaging algorithms are crucial for setting the right course of action.... Dieser…
View Post 15 min This content is machine translated Obesity, Nutrition, and Mental Health Depression, Binge Eating, Internalized Stigma Cardiometabolic outcomes rightly dominate obesity care. However, the psychological dimension is by no means a footnote: depression, disordered eating, and an often-overlooked internalized weight stigma influence the burden of disease,...…
View Post 10 min This content is machine translated Switzerland's First PTH Replacement Therapy Palopegteriparatide for Chronic Hypoparathyroidism Chronic hypoparathyroidism is one of the few endocrine disorders for which no causal hormone replacement therapy has been available for decades. Treatment focused not on the underlying hormone deficiency, but...…
View Post 5 min This content is machine translated Case study Orofacial Manifestations of Phelan-McDermid Syndrome Phelan-McDermid syndrome is a rare genetic disorder primarily caused by deletions or structural changes in chromosome 22q13. In a publication from 2025, De Falco et al. described the first documented...…
View Post 5 min This content is machine translated Colorectal Cancer Insulin Resistance, Obesity, and Progression Colorectal cancer is one of the most common malignant tumors worldwide and is increasingly linked to metabolic disorders such as insulin resistance and obesity. New epidemiological data show significant shifts...…
View Post 4 min This content is machine translated From symptom to diagnosis Abdominal Pain – Focal Nodular Hyperplasia Thanks to advances in imaging techniques, focal nodular hyperplasia of the liver is being detected with increasing frequency. Focal nodular hyperplasia is often an incidental finding. In some cases, patients...…
View Post 5 min This content is machine translated Case study Discoid Lupus Erythematosus in a 38-Year-Old Woman Discoid lupus erythematosus (DLE) accounts for 50–80% of all cases of chronic cutaneous lupus, making it the most common subtype. The diagnosis is primarily clinical but is supported by histopathology...…
View Post 18 min This content is machine translated From an antidiabetic drug to a distinct class of cardiorenal therapies The Incretin Revolution in Cardiology Within a decade, incretin mimetics have evolved from blood-sugar-lowering diabetes medications into one of the most dynamic classes of drugs in cardiovascular medicine. GLP-1 receptor agonists (GLP-1-RA) have been shown...…
View Post 3 min This content is machine translated Prostate Cancer Intracrine and Metabolic Tumor Adaptation Under Androgen Deprivation Androgen deprivation therapy (ADT) remains a cornerstone of prostate cancer treatment. It slows tumor growth but also triggers complex intracellular and metabolic response pathways. These tumor adaptations, which significantly influence...…
View Post 10 min This content is machine translated Alopecia areata in children, adolescents, and adults New Guideline Classifies the Evidence Base for Topical and Systemic Therapies The severity of alopecia areata has significant implications for counseling and treatment planning; however, to ensure the best possible care, the patient’s age, the individual impact of hair loss, and...…
View Post 12 min This content is machine translated Baxdrostat – a new class of drugs for treating difficult-to-control hypertension First Aldosterone Synthase Inhibitor Is Here It is the first new class of antihypertensive drugs in years: On May 18, 2026, the U.S. Food and Drug Administration (FDA) approved Baxdrostat (Baxfendy) as the first and only...…