This content is machine translated Treatment resistant depression Esketamine nasal spray as monotherapy? New for treatment-resistant depression Despite a variety of approved antidepressant treatments, major depressive disorder (MDD) remains one of the leading causes of disability worldwide and has been shown to shorten the life expectancy of...…
View Post 6 min This content is machine translated Analysis of SNVCS data from the period 2005-2022 TBE vaccination for children and adolescents in Switzerland The Swiss National Vaccination Study (SNVCS) is a nationwide cross-sectional study that evaluates the vaccination rate of children and adolescents aged 2, 8 and 16 years. In a combined cross-sectional...…
View Post 4 min This content is machine translated Tuberculosis Detecting diabetes in TB patients early and efficiently People with diabetes have a significantly increased risk of tuberculosis and poorer treatment outcomes, which is why systematic diabetes screening is recommended for TB patients. A meta-analysis showed that previously...…
View Post 4 min This content is machine translated HER2+ early breast cancer DESTINY-Breast11 – neoadjuvant T-DXd without anthracyclines The phase III DESTINY-Breast11 trial shows that neoadjuvant trastuzumab deruxtecan (T-DXd) could provide an anthracycline-free treatment option for HER2-positive early breast cancer. The results suggest an effective and better tolerated...…
View Post 3 min This content is machine translated Lavender aromatherapy Take away the fear of the dentist Fear of the dentist is still widespread and often leads to avoidance of treatment and a resulting deterioration in oral health. Supplementary non-pharmacological measures are increasingly being used to make...…
View Post 5 min This content is machine translated Mantle cell lymphoma Recurrence after BTK inhibition – prognostic factors and treatment options Mantle cell lymphoma (MCL) is a rare B-cell non-Hodgkin’s lymphoma with a markedly heterogeneous course. The spectrum ranges from indolent, slowly progressive forms to highly aggressive variants. Diagnosis and treatment...…
View Post 3 min This content is machine translated Dementia risk with type 2 diabetes SGLT2 inhibitors with advantages vs. DPP4 inhibitors SGLT2 inhibitors are associated with a significantly lower risk of dementia, including Alzheimer’s disease and vascular dementia, compared to DPP4 inhibitors. The observed benefit was consistent across different subgroups and...…
View Post 4 min This content is machine translated Cannabis for schizophrenia CBD pre-treatment could exacerbate side effects A significant proportion of people with schizophrenia use cannabis, with around one in five meeting the criteria for a comorbid cannabis use disorder, for which there are still limited effective...…
View Post 7 min This content is machine translated Case study 8-year-old girl with Pätau syndrome aka trisomy 13 The median survival time for live-born children with complete trisomy 13 without medical intervention is 7-10 days. Over 90% of affected newborns die in the first year of life. Risk...…
View Post 8 min This content is machine translated Urothelial carcinoma Immune and targeted therapy options: Evidence situation 2025/2026 The treatment of urothelial carcinoma has developed significantly in recent years. Modern immunotherapies, antibody-drug conjugates (ADCs) and targeted substances complement conventional chemotherapies and increasingly enable individualized treatment strategies. New data...…
View Post 5 min This content is machine translated SGLT2 inhibitors for type 2 diabetes and CKD Prediction model beats albuminuria threshold SGLT2 inhibitors also significantly reduce the risk of kidney disease progression in patients with type 2 diabetes and preserved kidney function, whereby the relative benefit is independent of albuminuria status....…
