This content is machine translated Mechanisms, evidence and therapeutic consequences GLP-1 receptor agonists in cardiology GLP-1 receptor agonists (GLP-1RAs) have rapidly evolved from antidiabetic drugs to cardiometabolic therapies with clinically proven reductions in hard cardiovascular endpoints – and increasingly beyond the traditional diabetes population. The...…
View Post 4 min This content is machine translated Early detection of type 1 diabetes Detection of insulin autoantibodies as an early marker Type 1 diabetes develops in several stages, whereby in the first preclinical phase only diabetes-specific autoantibodies are initially present in the blood, but the patients are normoglycaemic. Targeted screening is...…
View Post 3 min This content is machine translated Type 2 diabetes Smoking causes more than double the risk The characteristics of type 2 diabetes vary from patient to patient and the disease is thought to consist of four subtypes. However, a new study shows that smoking significantly increases...…
View Post 6 min This content is machine translated CKD: counteracting kidney progression and reducing the risk of CVD Targeted intervention through a multifactorial approach The Swiss Society of Nephrology (SGN) advocates targeted screening for defined risk groups. However, given the prevalence of chronic kidney disease (CKD) in primary care, it is hardly possible to...…
View Post 11 min This content is machine translated Alternative to insulin and GLP1 From the β-cell to the center: the versatile role of amylin Although amylin was discovered decades ago, its importance in everyday clinical practice has long been underestimated. New pharmacological developments are increasingly bringing amylin into the focus of diabetes and obesity...… CME-Test
View Post 6 min This content is machine translated Lipid management: ESC/EAS guideline update 2025 New recommendations on CVD risk classification, lipid lowering in statin intolerance and hoFH The European Society of Cardiology (ESC) and European Atherosclerosis Society (EAS) guideline update on the management of dyslipidemia continues to focus largely on how best to manage lipid levels to...…
View Post 15 min This content is machine translated Diabetes mellitus Treatment of comorbidities in older people One in five people over 65 and one in four people over 75 are affected by diabetes. Global projections predict a 2.5-fold increase in diabetes prevalence over the next 25...… CME-Test
View Post 15 min This content is machine translated Diabetes mellitus Treatment of comorbidities in older people One in five people over 65 and one in four people over 75 are affected by diabetes. Global projections predict a 2.5-fold increase in diabetes prevalence over the next 25...… CME-Test
View Post 5 min This content is machine translated Case Report 53-year-old female patient with palmoplantar keratoderma Palmoplantar keratoderma is characterized by excessive epidermal thickening of the skin on the palms and/or plantar surfaces of the feet and can be hereditary or acquired. The spectrum of possible...…
View Post 6 min This content is machine translated Update 2025 Hypercholesterolemia The past 18 months have noticeably shifted the LDL-lowering landscape: An ESC/EAS-Focused Update 2025 sharpens the indication thresholds, real-world data confirm the benefit of early combinations after myocardial infarction, bempedoic...…
View Post 4 min This content is machine translated GLP1-RA therapy Improvement in either weight or HbA1c – but never both Numerous studies show that glucagon-like peptide-1 receptor agonists (GLP1-RA) can significantly reduce the risk of diabetes-related complications and also reduce mortality. Despite their proven efficacy in trial designs, patient response...…
