This content is machine translated Heinz Nixdorf Recall Study When the heart vessels calcify – susceptibility also hereditary An interdisciplinary research team from the Medical Faculty of the University of Duisburg-Essen (UDE) has been able to prove that a person’s lifestyle is not the only factor responsible for…
View Post 13 min This content is machine translated Gene Therapy New ways in treatment Gene therapy, a long-time beacon of hope in medical research, is finally finding its way into the clinic to cure monogenetic diseases. This provides medicine with a new therapy that…
View Post 4 min This content is machine translated Cystic fibrosis Even one mutated gene increases the risk In autosomal recessive diseases such as cystic fibrosis (CF), one is dealing with the inheritance of two mutated genes. Previously, CFTR* expression levels of 50% were thought to be sufficient…
View Post 2 min This content is machine translated Migraine Common genetic variables to MS detected Although the symptoms and risk factors for migraine and multiple sclerosis (MS) often overlap, it is not known whether these two conditions are independent or share a common biological etiology,…
View Post 3 min This content is machine translated Immunotherapy Wider use for CAR-T cell treatment possible in the future? CAR-T cells have solved a central problem in cancer therapy – they make tumors visible again to the immune system. The initial successes in B-cell lymphomas are now attracting a…
View Post 6 min This content is machine translated Scar prevention Methods ranging from stem cells and autologous cell spray to laser and radiotherapy Prophylaxis of scars represents an important component of successful wound management. Nowadays, a wide range of invasive and non-invasive measures is available. At the EADV Annual Congress, international experts gave…
View Post 10 min This content is machine translated Multiple sclerosis Update on new antigen-specific therapeutic approaches A promising approach for the therapy of multiple sclerosis lies in antigen-specific treatment. They are intended to specifically inhibit the autoreactive immune response to avoid the risks of global immunosuppression.
View Post 2 min This content is machine translated CAR-T cells Focus on innovative cancer therapy CAR-T cells are currently one of the most exciting developments in immunotherapy. It combines immunotherapy, cell therapy and gene therapy and could become a routine treatment in the future.
View Post 10 min This content is machine translated Myeloproliferative neoplasms Polycythemia vera: pathogenesis, clinical, diagnostic and therapeutic implications. Hematopoietic stem cell myeloproliferative neoplasia is predominantly caused by somatic mutations of the JAK2 gene and resulting clonal autonomous hematopoiesis. The risk of myelofibrosis or leukemic transformation are prognostic.
View Post 10 min This content is machine translated Update Cardiogenetics Current advances and limitations in cardiovascular genetics. Genetic testing now enables diagnoses that could not be made in the past. However, it depends on the method, which significance is behind the results.
View Post 6 min This content is machine translated Anxiety disorders What is the role of epigenetics? “We are not our genes!” With this statement, Prof. Katharina Domschke from Freiburg referred to the importance of environmental influences – and how they shape our mental health through epigenetic…
