This content is machine translated Medicine and genetics Genetic counseling – when and for whom? Genetic counseling is voluntary, open-ended, non-directive, and comprehensive. The question is defined by the person seeking advice in his or her personal context. Anamnestic diagnoses must be questioned and checked…
View Post 3 min This content is machine translated Newly diagnosed multiple myeloma Does a proteasome inhibitor offer new therapeutic options? One study discussed at the ASH meeting involved a regimen consisting of oral MLN9708 administered twice weekly plus lenalidomide and dexamethasone in patients with newly diagnosed multiple myeloma. It concludes…
View Post 6 min This content is machine translated Interview at ASCO GI on new data from the OPUS study. “We are a good step closer to personalized therapy in mCRC” In the treatment of metastatic colorectal cancer, there were new results on subgroup analyses of the OPUS trial at this year’s ASCO GI in San Francisco. As previously shown in…
View Post 4 min This content is machine translated Metastatic colorectal carcinoma To what extent does aspirin affect survival? More recently, studies have shown that aspirin improves overall survival in subgroups with colorectal cancer, specifically those with PIK3CA mutations. To test whether regular aspirin use is associated with survival…
View Post 6 min This content is machine translated Nodal lymphoma from the pathology point of view Update for daily practice A persistent lymphadenopathy is a clear indication for further histopathological diagnosis. A detailed medical history as well as knowledge of previous diseases, manipulations and drug therapies are essential for a…
View Post 4 min This content is machine translated HER2-positive breast cancer and lymphoma New applications and antibodies The antibody-drug conjugate trastuzumab emtansine, T-DM1 (Kadcyla®), is composed of the antibody trastuzumab and the chemotherapeutic agent DM1 and is currently being investigated for the treatment of HER2-positive cancers. It…
View Post 4 min This content is machine translated Multiple Myeloma and MDS Something has happened in therapy The diagnosis and treatment of multiple myeloma (MM) and myelodysplastic syndromes (MDS) have undergone great development in recent years. Modern diagnostic procedures became qualitatively better and more widely available, new…
View Post 4 min This content is machine translated ASCO Congress What is the potential of adjuvant therapy and genetic analysis? Current research desiderata on melanoma were presented at this year’s ASCO Congress. Immunotherapy is considered the basis of today’s adjuvant treatment, as radiotherapy is no longer recommended due to too…
View Post 2 min This content is machine translated Trend Lecture Novartis Why we are not slaves to our genes n biochemist who can explain in a generally understandable way, without a manuscript or a PowerPoint presentation, how unique every human being is, may well be called particularly gifted. At…
