This content is machine translated Management of patients after alloHCST ERS/EBMT guideline recommendations on pulmonary cGvHD After an allogeneic stem cell transplant (alloHCST), life-threatening chronic graft-versus-host disease (cGvHD) occurs again and again. This is when the donor’s immune cells attack the recipient’s body. Lung involvement in...…
View Post 8 min This content is machine translated Progressive multiple sclerosis New horizons: from BTK inhibitors to remyelination The progressive forms of multiple sclerosis – primary progressive MS (PPMS) and secondary progressive MS (SPMS) – have presented neurologists with particular challenges for decades. Unlike relapsing-remitting MS (RRMS), where...…
View Post 4 min This content is machine translated Case series Bleeding prophylaxis for von Willebrand disease Von Willebrand’s disease is predominantly inherited in an autosomal dominant manner and is the most common hereditary cause of a bleeding tendency. It is caused by a quantitative and/or qualitative...…
View Post 6 min This content is machine translated Past, present and future Biomarkers in schizophrenia Schizophrenia is one of the most complex and serious psychiatric disorders. Despite decades of research, many of its causes remain unexplained. In recent years, interest in biomarkers has grown considerably,...…
View Post 7 min This content is machine translated From genome profiles to targeted therapies Advances in breast cancer therapy in the age of molecular diagnostics The treatment of breast cancer has undergone a profound transformation over the last two decades. While clinical-pathological parameters long formed the sole basis for therapy decisions, molecular diagnostics and personalized...…
View Post 5 min This content is machine translated Findings from the TRACK-FA study Neuroimaging biomarkers in Friedreich’s ataxia Friedreich’s ataxia (FA) is a rare, autosomal recessive neurodegenerative disease whose natural history and clinical characterization have made significant progress in recent decades. Nevertheless, there is still a lack of...…
View Post 16 min This content is machine translated Blastic plasmacytoid dendritic cell neoplasia Rare malignancy from a dermatological perspective Blastic plasmacytoid dendritic cell neoplasia (BPDCN) is an aggressive hematologic malignancy originating from immature plasmacytoid dendritic cell (PDC) precursors. The initial manifestation of BPDCN often consists of cutaneous lesions. In...… CME-Test
View Post 5 min This content is machine translated The autoimmune architecture of the child's INS From podocyte pathophysiology to personalized therapy Idiopathic nephrotic syndrome (INS) is the most common glomerular disease in childhood. For a long time, it was considered a clinically defined, non-specific entity whose treatment was primarily based on...…
View Post 16 min This content is machine translated IBDmatters - Synergy effects for IBD pathways How combination therapies lead to better treatment results Inflammatory bowel diseases ( IBD) are complex and multifactorial diseases that require a differentiated and evolving treatment approach. When monotherapies reach their limits, the need for combination strategies grows. The...… CME-Test
View Post 5 min This content is machine translated Idiopathic cholestasis Genotype-phenotype correlations in PFIC The EASL guidelines on the clinical management of hereditary cholestatic liver disease, published in 2024, suggest that genetic testing should be performed as early as possible in the diagnostic process...…
View Post 13 min This content is machine translated Potential biomarkers for diagnostics, prognosis and therapy Male infertility Male infertility represents a significant challenge in urological practice and is responsible for around 40-50% of all cases of involuntary childlessness in couples. Despite comprehensive clinical investigations, the exact cause...…
