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Pharmacology and toxicology

315 posts
  • This content is machine translated Parkinson's disease: progressive and clinically heterogeneous

Individualized management of motor and non-motor symptoms

Primary care providers are the central point of contact for the early detection of Parkinson’s disease, but collaboration with neurological specialists is essential. The diagnosis is still primarily made clinically....…
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  • 4 min
  • This content is machine translated Dementia

Delirium risks and treatment strategies

Delirium is a common and serious neuropsychiatric disorder in elderly hospitalized patients. A large review shows: Numerous medications increase the risk of delirium, especially opioids, antipsychotics, benzodiazepines and certain antibiotics....…
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  • 5 min
  • This content is machine translated How do weight loss interventions affect the muscles?

Reflective evaluation: do not neglect qualitative aspects

Both in the context of exclusively dietary interventions and after bariatric surgery or treatment with GLP(glucagon-like peptide)-1 analogs, there is not only a reduction in weight, but also a loss...…
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  • 6 min
  • This content is machine translated Obesity in the family practice

Aim for realistic goals and avoid apportioning blame

Morbid obesity is a significant health risk factor and its prevalence has increased in many industrialized countries in recent years. The principles of weight reduction have hardly changed over the...…
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  • 5 min
  • This content is machine translated Osteoporosis

Risk-stratified therapy with osteoanabolic agents improves outcomes

Patients with a very high or imminent fracture risk should be considered for (first-line) therapy with ostoanabolic substances. Both patient selection and planning of therapy sequences are decisive factors for...…
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  • 7 min
  • This content is machine translated Longevity Medicine 2025

From anti-ageing to precision prevention

Longevity Medicine in 2025 is less a marketing term than a clinical work program: moving away from fuzzy “anti-aging” promises towards measurable risk, biomarker and intervention logic. Drivers are a...…
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  • 5 min
  • This content is machine translated Side effects under opioid therapy

Is it possible to avoid the inevitable?

Opioid analgesics are an essential tool for the relief of cancer-related pain. However, in addition to their undeniable therapeutic value, opioids are associated with a number of predictable side effects...…
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  • 4 min
  • This content is machine translated Phobia

Propranolol and spider phobia: the time window is crucial

A new study on spider phobia shows that propranolol only works in the long term if those affected re-encounter the fear-inducing stimulus early on. This brings reconsolidation into sharper focus...…
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  • 3 min
  • This content is machine translated Sleep disorder

Sleep medicine in transition: new goals and a reassessment of old hypnotics

Sleep and circadian rhythm disorders (SCRDs) often occur as early comorbidities in neurodegenerative diseases such as Alzheimer’s disease (AD) and Parkinson’s disease (PD), often decades before typical symptoms appear. Sleep...…
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  • 4 min
  • This content is machine translated Epilepsy

Cannabidiol for refractory epilepsy syndromes

The pharmaceutical formulation of high-purity cannabidiol is approved for the treatment of seizures associated with Lennox-Gastaut syndrome, Dravet syndrome and tuberous sclerosis complex. Despite many years of clinical experience, there...…
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  • 4 min
  • This content is machine translated Pulmonary sarcoidosis

Prednisone vs. MTX: a draw after 24 weeks

Pulmonary sarcoidosis remains a persistent clinical challenge in respiratory medicine. Although glucocorticoids have long been the mainstay of first-line therapy, their side effects often complicate long-term treatment. In recent years,...…

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