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Pharmacology and toxicology

290 posts
  • This content is machine translated New practice guideline for fibromyalgia syndrome

Good times, bad times

Patients with fibromyalgia syndrome (FMS) have comparatively low muscle strength in the static and moving muscles. The most important thing is therefore to get patients moving. Regular exercise has been...…
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  • 5 min
  • This content is machine translated Glomerulonephritis: IgA nephropathy

Pathogenesis-based and nephroprotective therapeutic approaches

Immunoglobulin (Ig) A nephropathy is considered an important cause of end-stage renal failure. Therefore, from today’s perspective, IgA nephropathy should not be classified as a benign disease. Fortunately, the treatment...…
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  • 6 min
  • This content is machine translated Postmenopausal osteoporosis: long-term therapy concepts

Targeted use of antiresorptives and osteoanabolic agents and avoid “rebound” effects

Postmenopausal osteoporosis in women is a consequence of decreasing oestrogen levels and is associated with rapid bone loss (“high-turnover osteoporosis”). Long-term therapy concepts are required to achieve sustainable effects –...…
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  • 6 min
  • This content is machine translated Late-onset rheumatoid arthritis

More DMARDs can reduce glucocorticoids in LORA

Although glucocorticoids have no influence on the course of the disease, they are effective agents against symptomatic pain and inflammation in rheumatoid arthritis (RA). Patients with late onset RA (LORA)...…
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  • 16 min
  • This content is machine translated Pain and autism

Hurdles to pain treatment for autistic patients

In contrast to neurotypical patients, the brains of neurodivergent people develop differently from the norm. Autism is defined as a form of neurodivergence. For them, deviant stimulus processing is the...…
CME-Test
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  • 6 min
  • This content is machine translated Chronic musculoskeletal pain

How can the use of analgesics be optimized in multimodal therapy?

Musculoskeletal pain is complex and often underestimated. Pain sensitization plays an important role in chronification. In the long-term use of currently available analgesics, there may be conflicting goals with regard...…
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  • 2 min
  • This content is machine translated Chronic pain

Nano-ECS modulator Adezunap improves therapy success

Cannabinoids have established themselves as therapeutic options in the treatment of pain in recent years. Nevertheless, patients can experience problems when using them, particularly with regard to tolerance. A new...…
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  • 4 min
  • This content is machine translated Gastrointestinal complaints

PPI regulation under the microscope

Proton pump inhibitors (PPIs) are very effective and suitable for certain indications and treatment periods, but there is an increasing trend towards “off-label” prescriptions. To ensure that temporary administration for...…
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  • 3 min
  • This content is machine translated "Patients W.A.I.T. Indicator"

Access to new drugs is becoming increasingly difficult

Switzerland is slipping further down the European rankings when it comes to access to new innovative medicines: according to IQVIA’s EFPIA WAIT Indicator 2024, Switzerland has dropped another place, falling...…
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  • 5 min
  • This content is machine translated Postoperative cognitive dysfunction

Effects of midazolam and dexmedetomidine

With demographic change and the rising average age of cardiology patients, post-operative cognitive dysfunction (POCD) following heart surgery is becoming increasingly important in clinical terms. If it occurs, patients often...…
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  • 6 min
  • This content is machine translated Cannabis - medical vs. non-medical use

Interim assessment: the boundaries are fluid

Although it has been possible to obtain a prescription for cannabis medicines in Switzerland for a number of years, it is not uncommon for patients to incur considerably higher costs...…

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