This content is machine translated New perspectives for the optimization of cancer immunotherapy Nanoparticle-mediated intratumoral gene editing of PD-L1 and galectin-9 Immune checkpoint inhibitors (ICI) have revolutionized oncological therapy, but many patients do not respond or only respond inadequately to this form of treatment. Resistance mechanisms such as the overexpression of...…
View Post 6 min This content is machine translated Past, present and future Biomarkers in schizophrenia Schizophrenia is one of the most complex and serious psychiatric disorders. Despite decades of research, many of its causes remain unexplained. In recent years, interest in biomarkers has grown considerably,...…
View Post 4 min This content is machine translated Asthma and type 2 diabetes Unholy alliance Previous studies have shown that patients with asthma have an increased risk of developing type 2 diabetes and that people with type 2 diabetes have an increased risk of developing...…
View Post 7 min This content is machine translated From genome profiles to targeted therapies Advances in breast cancer therapy in the age of molecular diagnostics The treatment of breast cancer has undergone a profound transformation over the last two decades. While clinical-pathological parameters long formed the sole basis for therapy decisions, molecular diagnostics and personalized...…
View Post 6 min This content is machine translated Current overview of evidence, mechanisms and clinical implications Apolipoprotein E and neuropsychiatric symptoms in neurocognitive disorders Neuropsychiatric symptoms (NPS) such as depression, anxiety, apathy, psychosis or behavioral disorders are among the most common concomitant symptoms of neurocognitive disorders and have just as strong an impact on...…
View Post 12 min This content is machine translated Parkinson's disease Individual therapy management for an optimized outcome – an update Parkinson’s disease is one of the most common neurodegenerative diseases, which manifests itself with motor symptoms such as slowness of movement (bradykinesia), tremors at rest (resting tremor) and muscle stiffness...… CME-Test
View Post 6 min This content is machine translated Latent autoimmune diabetes in adults (LADA) Looks like type 2, but is type 1 Type 1 diabetes can occur in any age group. In adults, however, type 2 diabetes (T2DM) is often diagnosed first, and autoantibodies indicative of T1DM are only detected later. The...…
View Post 6 min This content is machine translated Treatment of vitiligo Focus on patient perspective and disease activity In vitiligo, hypopigmented or depigmented areas of skin occur as a result of an autoimmune disorder. The results of a large international survey confirm that vitiligo sufferers sometimes experience considerable...…
View Post 5 min This content is machine translated Vaccine-preventable respiratory diseases RSV and pneumococci: recommendations for risk groups In addition to the known risks of respiratory syncytial virus (RSV) infections in newborns, infants and young children, it has recently emerged thatS RSV also poses significant health risks for...…
View Post 5 min This content is machine translated Circadian rhythm in asthma Chronotherapy can improve control Asthma is characterized by a pronounced diurnal rhythm, with symptoms worsening at night. Adjusting the timing of medication to the rhythm of the disease (chronotherapy) can improve the effectiveness of...…
View Post 6 min This content is machine translated Update on diagnostics, risk stratification and therapy Acute myeloid leukemia 2025 Acute myeloid leukemia (AML) remains one of the greatest challenges in hematology. Despite established chemotherapy protocols, the prognosis for many patients remains unfavorable. In recent years, however, new molecular classifications,...…
