This content is machine translated Acute lymphoblastic leukemia Addition of blinatumomab to chemotherapy improves survival in children Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. Children with newly diagnosed B-cell acute lymphoblastic leukemia (B-ALL) with standard risk (SR) have a high survival rate when treated...…
View Post 3 min This content is machine translated Advanced breast cancer Next-generation SERD therapy with promising results The results of the Phase III EMBER-3 trial of imlunestrant, a next-generation oral selective oestrogen receptor degrader (SERD) for patients with hormone receptor-positive breast cancer in ER-positive, HER2-negative advanced breast...…
View Post 6 min This content is machine translated Urticaria & urticaria-like exanthema Case studies from pediatric dermatology The lifetime prevalence of urticaria is almost 20%. Second-generation antihistamines are also recommended as first-line therapy for pediatric patients. However, pediatric patients with itchy wheals are not always suffering from...…
View Post 6 min This content is machine translated Vitiligo in children and adolescents Just don’t bury your head in the sand! This dermatosis, which is based on the destruction of melanocytes, can occur at any age – however, it usually affects 10-30 year olds and in over a third of cases...…
View Post 4 min This content is machine translated Innovative care concepts: HÄPPI project Future-oriented model for interprofessional primary care New care models are innovative forms of cooperation and service provision in outpatient primary medical care that offer higher quality and are more efficient at the same time. In Baden-Württemberg,...…
View Post 7 min This content is machine translated Moderate to severe chronic hand eczema Delgocitinib cream – first topical pan-JAK inhibitor approved in Switzerland In the phase III DELTA 1 and 2 studies, delgocitinib cream showed a rapid onset of efficacy – at week 16, half of the patients achieved a 75% improvement in...…
View Post 5 min This content is machine translated Study on tinnitus in everyday practice ENT specialists rely on Ginkgo biloba A retrospective cohort study published in 2024 analyzed how frequently ENT specialists prescribed ginkgo biloba extract, systemic corticosteroids or pentoxifylline to patients with newly diagnosed tinnitus. The analysis was based...…
View Post 3 min This content is machine translated Hodgkin's lymphoma No more transplants for relapsed or refractory HL in the future? The standard treatment approach for relapsed or refractory (RR) classical Hodgkin’s lymphoma (HL) after failure of first-line treatment is second-line therapy with the aim of achieving complete remission (CR), followed...…
View Post 5 min This content is machine translated Obesity in childhood and adolescence Multifactorial disease with multiple implications The prevalence of obesity in children and adolescents has risen in recent decades. The categorization of BMI is age- and gender-specific. Studies show that BMI status at a young age...…
View Post 3 min This content is machine translated Gram-negative foot infection Not to be taken lightly Infections of wounds in the foot area are common and correct classification is sometimes a challenge. In Gram-negative foot infections, clinical findings form the backbone of the diagnosis. Local therapy...…
View Post 4 min This content is machine translated CHD: Management after revascularization Individualization of antithrombotic therapy Coronary heart disease (CHD) is one of the most common heart diseases worldwide and is currently grouped into two syndromes: acute coronary syndrome (ACS) and chronic coronary syndrome (CCS). Following...…
