This content is machine translated Psoriasis Research: What's in the Pipeline? Highly selective oral TYK inhibitors in Phase III Envudeucitinib and Zasocitinib are oral, allosteric tyrosine kinase 2 (TYK2) inhibitors currently being evaluated in clinical trials for plaque psoriasis. The interim results presented during the Late-Breaking Research sessions at...…
View Post 3 min This content is machine translated Asthma in Adults: Bronchodilation and Anti-Inflammatory Therapy Remodeling can be counteracted through a proactive treatment strategy If certain key, evidence-based principles are followed, remission is now an achievable goal in asthma treatment. First, it is recommended to routinely supplement spirometry with a blood test to measure...…
View Post 6 min This content is machine translated Autoimmune Liver Diseases Innovative Treatment Approaches for PBC, PSC, and AIH: What’s New? PPAR agonists as second-line therapy have proven effective in primary biliary cholangitis (PBC) not only in clinical trials but also in real-world settings, as recent research findings show. In primary...…
View Post 7 min This content is machine translated cSCC: Personalizing Treatment Strategies and Follow-up Care Plans Comprehensive risk stratification is no simple matter: what’s new? Cutaneous squamous cell carcinoma (cSCC) is currently the second most common type of skin cancer, and the number of cases continues to rise. While surgical resection alone is considered the...…
View Post 5 min This content is machine translated Irritable Bowel Syndrome IBS or endometriosis? Chronic pelvic pain ( CPP) is a common reason for referral to gynecology departments and is commonly attributed to endometriosis. However, gastrointestinal disorders, particularly irritable bowel syndrome (IBS), have several...…
View Post 6 min This content is machine translated Type 2 diabetes: sarcopenia and frailty How can the breakdown of skeletal muscles be stopped? Insulin resistance, dyslipidemia, lack of exercise, inflammation and hypertension are among the most common risk factors for sarcopenia. Along with a loss of muscle mass and function, the risk of...…
View Post 4 min This content is machine translated MASH Pharmacotherapies as “Game Changers”—What Are the Upcoming Challenges? Two drug therapy options—semaglutide (s.c.) and resmetirom (oral)—are now approved in the EU and the U.S. for the treatment of MASH. This is a major breakthrough, especially since, for a...…
View Post 4 min This content is machine translated Cholangiocarcinoma Modern molecular diagnostics and targeted therapy options Cholangiocarcinoma (CCA) is one of the most aggressive tumors of the hepatobiliary system and is often only diagnosed at an advanced stage. Advances in molecular diagnostics and targeted therapy are...…
View Post 6 min This content is machine translated Treatment resistant depression Esketamine nasal spray as monotherapy? New for treatment-resistant depression Despite a variety of approved antidepressant treatments, major depressive disorder (MDD) remains one of the leading causes of disability worldwide and has been shown to shorten the life expectancy of...…
View Post 7 min This content is machine translated Actinic keratoses Targeted Treatment of Multiple AK Lesions—Balancing Efficacy and Convenience Actinic keratoses occur singly or in confluent patches on sun-exposed areas of the skin. Clinical and/or dermatoscopic diagnosis can be supported by non-invasive diagnostic tools such as confocal microscopy and...…
View Post 6 min This content is machine translated Analysis of SNVCS data from the period 2005-2022 TBE vaccination for children and adolescents in Switzerland The Swiss National Vaccination Study (SNVCS) is a nationwide cross-sectional study that evaluates the vaccination rate of children and adolescents aged 2, 8 and 16 years. In a combined cross-sectional...…
