This content is machine translated Advanced solid tumors Survival Plateaus with Botensilimab + Balstilimab At the 2025 ESMO Congress, a wealth of data on solid tumors was presented. This included an updated analysis of the combination of botensilimab and balstilimab.... Dieser Inhalt ist nur…
View Post 7 min This content is machine translated Eosinophils in the Blood in COPD How many measurements are needed to be sure? Approximately 20–40% of all COPD patients exhibit Type 2 inflammation, which is characterized by elevated BEC. This eosinophilic phenotype is associated with an increased risk of exacerbations and a favorable...…
View Post 6 min This content is machine translated Soft-tissue sarcomas of the upper extremities Immunotherapy and Molecular Targets New immunotherapy strategies for soft tissue sarcomas were presented at the 2026 ASCO Annual Meeting. The focus was on biomarker-based approaches using pembrolizumab and PD-L1 inhibition, which are also gaining...…
View Post 6 min This content is machine translated C3 glomerulopathy—can its progression be halted? Iptacopan and Pegcetacoplan Open Up New Horizons To diagnose C3 glomerulopathy (C3G) and distinguish it from other membranoproliferative glomerulopathies, a kidney biopsy is required in addition to measuring the concentration of the complement protein C3 in the...…
View Post 4 min This content is machine translated From symptom to diagnosis Abdominal Pain – Von Meyenburg Complexes of the Liver Von Meyenburg complexes are believed to be a congenital malformation arising from embryonic remnants of the bile ducts. Based on current knowledge, these benign, tumor-like biliary hamartomas do not lead...…
View Post 6 min This content is machine translated CKD: Cardiorenal Benefits of nsMRA and GLP-1RA FIND-CKD and FLOW: Benefits Across Heterogeneous Patient Populations Finerenon significantly slowed the decline in kidney function in non-diabetic adults with chronic kidney disease (CKD) and also reduced the risk of cardiovascular complications —according to recently published data from...…
View Post 8 min This content is machine translated IgA Nephropathy: The Evolving Landscape of Treatment What are the most important game-changers? IgA nephropathy, also known as “Berger’s disease,” is the most common form of glomerulonephritis worldwide. It is an immune-mediated kidney disease diagnosed based on urine test results and a kidney...…
This content is machine translated Chronic Lymphocytic Leukemia (CLL) Personalized Therapy in the Age of Targeted Drugs New data on the use of pirtobrutinib in treatment-naive patients with chronic lymphocytic leukemia were presented at the 2026 ASCO Annual Meeting. The results from the Phase 3 studies BRUIN...…
View Post 3 min This content is machine translated HGSOC PARP-based, molecular, and immunological therapeutic approaches At ASCO 2026, various therapeutic approaches for high-grade serous ovarian cancer (HGSOC) were presented. These included current data on genome-wide HRD characterization in the context of PARP maintenance therapy and...…
View Post 4 min This content is machine translated Multiple sclerosis Physical and psychosocial fatigue have the greatest impact on HRQoL Fatigue is one of the most common and debilitating symptoms of multiple sclerosis (MS); it affects up to 75% of MS patients and contributes to a poorer quality of life,...…
View Post 4 min This content is machine translated Hepatitis B: New Analysis of the B-SURE Study Bepirovir without prior nucleoside analog therapy Innovative therapies focus either on reducing viral load or on stimulating HBV-specific immune cells—or both. The B-CLEAR study on bepirovir included two parallel cohorts: HBV patients with and without prior...…
