This content is machine translated Cardiology and Nutrition Ultra-Processed Foods and Cardiovascular Risk—The New AHA Position Ultra-processed foods (UPFs ) account for a significant portion of energy intake in Western countries—in the United States, an estimated more than half. Given this ubiquity and a growing number...…
View Post 7 min This content is machine translated Obesity: A Multimodal and Interdisciplinary Approach New Swiss Clinical Practice Guideline Provides Guidance The guidelines developed by Swiss professional associations (Swiss Obesity Clinical Practice Guidance) contain evidence-based recommendations for the diagnosis and treatment of obesity, with a focus on improving health, quality of...…
View Post 6 min This content is machine translated Preclinical study on phytotherapeutic agent Active ingredient combination of peppermint and caraway oil modified fecal microbiota In an in-vitro study published in the journal Frontiers in Pharmacology in 2025, the effects of the active ingredient Menthacarin® on the composition of the human intestinal flora and the...…
View Post 11 min This content is machine translated Cardiometabolism Retatrutid and the TRIUMPH Program: The Triple Agonist on the Horizon Incretin-based obesity therapy has advanced rapidly in just a few years: from GLP-1 receptor agonists (semaglutide) to the dual GIP/GLP-1 agonist tirzepatide and on to a triple agonist. Retatrutide (LY3437943)...…
View Post 4 min This content is machine translated Casuistry Rituximab used effectively against IgG4-RD colitis IgG4-related disease (IgG4-RD) is a rare immune-mediated, fibroinflammatory disease characterized by IgG4-rich lymphoplasmacytic infiltrates with potential multiple organ involvement. Gastrointestinal manifestations are rare but may closely resemble inflammatory bowel disease,...…
View Post 12 min This content is machine translated Hepatology and Metabolism The Mediterranean Diet for MASLD/MASH—What the EASL-EASD-EASO Guidelines Specifically Recommend Since an international Delphi consensus in 2023, the condition formerly known as nonalcoholic fatty liver disease (NAFLD) has been called MASLD— “metabolic dysfunction-associated steatotic liver disease.” It is defined as...…
View Post 6 min This content is machine translated Upper GI Tract Bleeding: Hematemesis, Hematochezia, or Melena? From Risk Stratification to Post-Endoscopic Management Managing patients with acute upper gastrointestinal bleeding can be a balancing act. Clinical scores are helpful for time-sensitive risk assessment in the emergency department: Is the patient stable? Is urgent...…
View Post 15 min This content is machine translated Obesity, Nutrition, and Mental Health Depression, Binge Eating, Internalized Stigma Cardiometabolic outcomes rightly dominate obesity care. However, the psychological dimension is by no means a footnote: depression, disordered eating, and an often-overlooked internalized weight stigma influence the burden of disease,...…
View Post 5 min This content is machine translated Sarcoidosis New options from JAKi to mTOR Despite decades of clinical experience, the treatment of sarcoidosis remains a challenge. Although established treatment strategies such as corticosteroids, methotrexate or TNF-alpha blockers are available, the options are limited, particularly...…
View Post 10 min This content is machine translated Switzerland's First PTH Replacement Therapy Palopegteriparatide for Chronic Hypoparathyroidism Chronic hypoparathyroidism is one of the few endocrine disorders for which no causal hormone replacement therapy has been available for decades. Treatment focused not on the underlying hormone deficiency, but...…
View Post 6 min This content is machine translated Head and neck squamous cell carcinoma Precision immunotherapy and local treatment The role of immunotherapy in the treatment of locally advanced head and neck squamous cell carcinoma (LA-HNSCC) is currently being reassessed. At the SOHC Congress 2025 in Basel, Yungan Tao...…