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5951 posts
  • This content is machine translated Plastic surgery and reconstructive microsurgery for DFS

Functional limb preservation between infection control, vascular medicine and resurfacing

Diabetic foot syndrome (DFS) is one of the most serious and functionally significant complications of diabetes, with a high number of functionally relevant amputations. DFS is not to be understood...…
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  • 12 min
  • This content is machine translated SURPASS-CVOT

Tirzepatide versus Dulaglutide in T2D with ASCVD

GLP-1 receptor agonists have established themselves in recent years as a class of drugs with cardiovascular protective effects in type 2 diabetes. For dulaglutide, the 2019 REWIND study showed that...…
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  • 6 min
  • This content is machine translated Secondary prevention after ACS: individually optimized lipid management

Trend towards early combination therapy and new strategies for lowering Lp(a)

Secondary prevention after an acute coronary syndrome (ACS) is crucial for improving quality of life and reducing morbidity and mortality rates. Elevated blood lipid levels such as LDL cholesterol and...…
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  • 27 min
  • This content is machine translated Pediatric Brain Tumors

Psychiatry versus Neuro-Oncology: Diagnostic Pitfalls

Pediatric brain tumors often begin with nonspecific symptoms—some physical, some behavioral—that can be attributed to internal medicine or psychiatric differential diagnoses, thereby presenting typical diagnostic pitfalls. Clinical case examples from...…
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  • 13 min
  • This content is machine translated What the latest studies on the entire EF spectrum mean for clinical practice

Heart Failure – The 2026 Evidence Update

Since the release of the 2021 ESC guidelines and the 2022 AHA/ACC/HFSA guidelines, research on heart failure has reached a remarkable level of intensity. Nonsteroidal mineralocorticoid receptor antagonists and incretin-based...…
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  • 5 min
  • This content is machine translated Acute ischemic stroke

Alteplase and Tenecteplase Are on the Same Level

In acute ischemic stroke (AIS), rapid reperfusion therapy is a clinical priority. Although alteplase has been the standard thrombolytic agent for many years, its short half-life requires administration as a...…
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  • 5 min
  • This content is machine translated CKD in People with Type 2 Diabetes: Evidence-Based, Optimized Treatment

SGLT-2 inhibitors and GLP-1 receptor agonists: significant improvement in renal outcomes

Approximately 30–40% of patients with type 2 diabetes develop chronic kidney disease (CKD) over time. In “landmark” studies such as CREDENCE, DAPA-CKD, EMPA-KIDNEY, and several others, SGLT-2 (sodium-glucose-linked transporter 2)...…
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  • 2 min
  • This content is machine translated Wearables: screening via smartwatch?

New study on atrial fibrillation in high-risk patients

Wearable devices with photoplethysmography and ECG capabilities offer a non-invasive and scalable method of monitoring heart rate. A recently published randomized controlled trial provided evidence that six months of screening...…
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  • 13 min
  • This content is machine translated Planning a Family, Pregnancy, and Breastfeeding

Update on Anti-Rheumatic Medications

The 2024 EULAR recommendations on the use of antirheumatic medications during reproduction, pregnancy, and breastfeeding replace the previous recommendations from 2016. During this period, studies on the safety of biologics...…
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  • 5 min
  • This content is machine translated Mental Health with GLP-1 RAs

Benefits of Semaglutide and Liraglutide

GLP-1 receptor agonists are established treatments for type 2 diabetes and obesity. Depression and anxiety disorders are common among people with diabetes and obesity, and both conditions are associated with...…
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  • 4 min
  • This content is machine translated Bronchiolitis obliterans

Out of shape even without popcorn

Post-infectious bronchiolitis obliterans (PIBO) develops in childhood and is characterized by irreversible airway obstruction and persistent impairment of lung function. Although it is known that exercise capacity may be impaired,...…

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