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6020 posts
  • This content is machine translated New COPD Treatments

Targeting the inflammation—but for whom and when?

Up to 50% of people with COPD continue to experience exacerbations despite receiving maximum inhaled therapy. The key factor here is persistent chronic inflammation, which cannot be fully controlled even...…
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  • 5 min
  • This content is machine translated Tourette Syndrome

What can be done to treat this tic disorder?

Gilles de la Tourette syndrome (or “Tourette syndrome” for short) is a neurodevelopmental disorder characterized by motor and vocal tics and often accompanied by attention deficits, hyperactivity, and obsessive-compulsive disorder....…
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  • 4 min
  • This content is machine translated Chronic Hepatitis B: Is a Cure in Sight?

Phase III Trial of Temporary Treatment with Bepirovirsen Was Successful

Hepatitis B is the most common form of viral hepatitis worldwide—dreaded complications include liver cirrhosis and hepatocellular carcinoma (HCC). Treatment with Bepirovirsen, an antisense oligonucleotide that targets mRNAs of the...…
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  • 14 min
  • This content is machine translated Fibromyalgia Syndrome

Development, Diagnosis, Epidemiology, and Treatment of a Disease Entity

According to the 2010 and 2011 ACR diagnostic criteria, as revised in 2016, fibromyalgia syndrome is a multisymptomatic disorder whose primary symptom is chronic tendon-muscle pain that shifts and spreads...…
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  • 5 min
  • This content is machine translated Clinically Suspected Arthralgias

“Watchful waiting” or intervention?

The pathogenesis of rheumatoid arthritis (RA) begins years before clinical manifestation, but not all patients with joint pain develop RA. Since the primary care physician or internist’s office is usually...…
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  • 3 min
  • This content is machine translated Tumors of the Calcaneus

Diagnostic Challenges of Rare Heel Tumors

Tumors of the calcaneus are rare but diagnostically challenging. Nonspecific symptoms often lead to a delayed diagnosis. Diagnostic imaging algorithms are crucial for setting the right course of action.... Dieser…
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  • 6 min
  • This content is machine translated Upper GI Tract Bleeding: Hematemesis, Hematochezia, or Melena?

From Risk Stratification to Post-Endoscopic Management

Managing patients with acute upper gastrointestinal bleeding can be a balancing act. Clinical scores are helpful for time-sensitive risk assessment in the emergency department: Is the patient stable? Is urgent...…
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  • 15 min
  • This content is machine translated Obesity, Nutrition, and Mental Health

Depression, Binge Eating, Internalized Stigma

Cardiometabolic outcomes rightly dominate obesity care. However, the psychological dimension is by no means a footnote: depression, disordered eating, and an often-overlooked internalized weight stigma influence the burden of disease,...…
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  • 5 min
  • This content is machine translated From Hypertension to Heart Failure?

When and how to intervene

High blood pressure and hypertensive heart disease are the most significant risk factors for heart failure. The symptoms are very nonspecific, especially in the early stages of heart failure. Measuring...…
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  • 10 min
  • This content is machine translated Switzerland's First PTH Replacement Therapy

Palopegteriparatide for Chronic Hypoparathyroidism

Chronic hypoparathyroidism is one of the few endocrine disorders for which no causal hormone replacement therapy has been available for decades. Treatment focused not on the underlying hormone deficiency, but...…
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  • 5 min
  • This content is machine translated Case study

Orofacial Manifestations of Phelan-McDermid Syndrome

Phelan-McDermid syndrome is a rare genetic disorder primarily caused by deletions or structural changes in chromosome 22q13. In a publication from 2025, De Falco et al. described the first documented...…

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