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5921 posts
  • This content is machine translated Acute ischemic stroke

Alteplase and Tenecteplase Are on the Same Level

In acute ischemic stroke (AIS), rapid reperfusion therapy is a clinical priority. Although alteplase has been the standard thrombolytic agent for many years, its short half-life requires administration as a...…
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  • 5 min
  • This content is machine translated CKD in People with Type 2 Diabetes: Evidence-Based, Optimized Treatment

SGLT-2 inhibitors and GLP-1 receptor agonists: significant improvement in renal outcomes

Approximately 30–40% of patients with type 2 diabetes develop chronic kidney disease (CKD) over time. In “landmark” studies such as CREDENCE, DAPA-CKD, EMPA-KIDNEY, and several others, SGLT-2 (sodium-glucose-linked transporter 2)...…
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  • 2 min
  • This content is machine translated Wearables: screening via smartwatch?

New study on atrial fibrillation in high-risk patients

Wearable devices with photoplethysmography and ECG capabilities offer a non-invasive and scalable method of monitoring heart rate. A recently published randomized controlled trial provided evidence that six months of screening...…
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  • 13 min
  • This content is machine translated Planning a Family, Pregnancy, and Breastfeeding

Update on Anti-Rheumatic Medications

The 2024 EULAR recommendations on the use of antirheumatic medications during reproduction, pregnancy, and breastfeeding replace the previous recommendations from 2016. During this period, studies on the safety of biologics...…
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  • 11 min
  • This content is machine translated Peristomal skin health

Focus on preventive care options

For people with a stoma, peristomal skin health is a key factor for quality of life. With an incidence of up to over 70%, skin complications in the stoma area...…
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  • 5 min
  • This content is machine translated Mental Health with GLP-1 RAs

Benefits of Semaglutide and Liraglutide

GLP-1 receptor agonists are established treatments for type 2 diabetes and obesity. Depression and anxiety disorders are common among people with diabetes and obesity, and both conditions are associated with...…
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  • 4 min
  • This content is machine translated Bronchiolitis obliterans

Out of shape even without popcorn

Post-infectious bronchiolitis obliterans (PIBO) develops in childhood and is characterized by irreversible airway obstruction and persistent impairment of lung function. Although it is known that exercise capacity may be impaired,...…
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  • 8 min
  • This content is machine translated Case study

Guillain-Barré syndrome with a fulminant course

A 38-year-old male patient experienced a transient loss of all brainstem reflexes as part of an unusual course of Guillain-Barré syndrome, which, despite preserved cortical functions, resembled a coma or...…
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  • 5 min
  • This content is machine translated Suspicion of neuroborreliosis?

Detection of borrelia-specific CSF parameters provides certainty

A neurological manifestation occurs in 3-15% of Lyme borreliosis infections and can manifest itself, for example, as polyradiculitis, meningitis or, in rare cases, encephalomyelitis. If neuroborreliosis is suspected, it is...…
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  • 12 min
  • This content is machine translated The Brain and the Motivation to Eat

Why is it so hard to lose weight?

Obesity is the most common chronic disease in Western societies, with serious metabolic, cardiovascular, and psychosocial consequences. The therapeutic landscape has changed fundamentally: new-generation GLP-1 agonists achieve weight loss that,...…
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  • 12 min
  • This content is machine translated Global Recommendation, Swissmedic Approval, and SL Limitation

WHO Guidelines on GLP-1 for Obesity

With the guideline published on December 1, 2025, the World Health Organization has, for the first time, issued a globally applicable recommendation on the pharmacological management of obesity in adults....…

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    Personalized Treatment Before a Planned Pregnancy

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