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5957 posts
  • This content is machine translated Pathogenesis, diagnostics and therapeutic interventions

Sarcopenia in Parkinson’s disease

Parkinson’s disease and sarcopenia are two signs of ageing that mutually reinforce each other: While PD is characterized by the progressive loss of nigrostriatal dopamine neurons and abnormal α-synuclein deposits,...…
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  • 4 min
  • This content is machine translated Casuistry

63-year-old with tracheobronchopathia osteoplastica

This case study concerns an elderly patient who was admitted to hospital due to a cough with bloody sputum. After lengthy investigations, a diagnosis of tracheobronchopathia osteoplastica was made. This...…
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  • 7 min
  • This content is machine translated 2025 ACC/AHA/ACEP/NAEMSP/SCAI Guideline

Management of acute coronary syndrome

Every day, thousands of patients worldwide enter emergency departments with acute chest pain, shortness of breath or atypical symptoms. The differential diagnosis of acute coronary syndrome (ACS) is always one...…
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  • 4 min
  • This content is machine translated Pustular psoriasis

What is known about inflammatory mechanisms in PPP and GPP?

Pustular psoriasis is characterized by the sudden appearance of small, pus-filled blisters (“pustules”). The clinical, pathological and genetic features of GPP and PPP differ from plaque psoriasis. While in GPP...…
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  • 7 min
  • This content is machine translated Diabetes-related cardiovascular diseases

Ferroptosis: key mechanisms and novel therapeutic approaches

The global increase in diabetes mellitus is leading to a parallel increase in the incidence of cardiovascular complications, which remain the leading cause of death in this patient group. In...…
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  • 4 min
  • This content is machine translated Atrial fibrillation

What’s new with the “pace-and-ablate” strategy?

Atrial fibrillation (AF) is the most common cardiac arrhythmia and is associated with increased morbidity and mortality. The guideline of the European Society for Cardiology (ESC), which was updated last...…
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  • 3 min
  • This content is machine translated De-escalation strategies

De-escalation strategies – less is more

Drug de-escalation is primarily driven by the need to spare patients unnecessary toxicity and the associated side effects and repeated hospital visits. However, de-escalation strategies may also have the potential...…
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  • 5 min
  • This content is machine translated Pathogens in the brain

When infections trigger strokes

Infectious strokes are rarer than those caused by classic vascular risk factors, but play a significant role, particularly in resource-poor regions. Bacterial, viral, fungal and parasitic pathogens can directly damage...…
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  • 15 min
  • This content is machine translated Diabetes mellitus

Treatment of comorbidities in older people

One in five people over 65 and one in four people over 75 are affected by diabetes. Global projections predict a 2.5-fold increase in diabetes prevalence over the next 25...…
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  • 15 min
  • This content is machine translated Pulmonary hypertension

PH and lung diseases

Pulmonary hypertension (PH) describes a hemodynamic condition with a pathological increase in pressure in the pulmonary vascular circulation. Clinically, PH causes reduced performance, shortness of breath, angina and syncope. In...…
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  • 0 min
  • This content is machine translated Advanced NSCLC

MARIPOSA: Combination therapy as the new standard of care for EGFR-mutated NSCLC

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