This content is machine translated Urothelial carcinoma The role of checkpoint inhibitors Immunotherapy is also becoming increasingly important in the treatment of urothelial carcinoma. Checkpoint inhibitors are already being used successfully, particularly in advanced tumors. Now, potential applications of avelumab, atezolizumab and…
View Post 14 min This content is machine translated Focus on diabetes and heart New studies and new recommendations Study data in recent years have highlighted the enormous extent to which type 2 diabetes mellitus (T2D) promotes the development of cardiovascular disease. In addition, it became clear that certain…
View Post 3 min This content is machine translated Heart failure SGLT-2 inhibitors – great therapeutic potential in HFrEF patients. In addition to the SGLT-2 inhibitor dapagliflozin, which was also approved by Swissmedic last July for the treatment of heart failure (HFrEF) in non-diabetics, another member of this drug class,…
View Post 2 min This content is machine translated Advanced high-grade serous ovarian cancer. HRD+ tumors: first PARP inhibitor approved for first-line maintenance therapy As the first and only PARP inhibitor, olaparib was recently approved by swissmedic for first-line maintenance therapy in patients with advanced, HRD-positive ovarian cancer. The addition of olaparib to bevacizumab resulted…
View Post 2 min This content is machine translated Heart failure Effectively reduce re-hospitalization in patients with iron deficiency Intravenous iron (III) carboxymaltose results in significantly fewer hospital readmissions in patients with heart failure and iron deficiency compared with placebo. This is the conclusion of a study published in…
View Post 5 min This content is machine translated Prevention of non-melanocytic skin cancer (NMSC). Nicotinamide – blockbuster among cell-protective substances It is well known that UV radiation exposure is considered a major cause of non-melanocytic skin cancer by damaging DNA and inhibiting antitumor immunity. A reduction in intracellular ATP concentration,…
View Post 4 min This content is machine translated BRAFV600E-mutated metastatic colorectal cancer (mCRC). Evidence for additional benefit of dual blockade An expert panel finds considerable added benefit in the dual-blockade encorafenib combined with cetuximab in the treatment of metastatic colorectal cancer with BRAFV600E mutation after prior systemic therapy. This is…
View Post 3 min This content is machine translated Myocardial infarction Survived a heart attack – and now? Post-infarct management up-to date After an acute myocardial infarction, postinfarction management is the focus of treatment. To prevent another coronary event, it is essential to identify and treat appropriate risk factors. Non-drug interventions have…
View Post 5 min This content is machine translated Chronic lymphocytic leukemia BTK inhibitors and other hopefuls The therapy of chronic lymphocytic leukemia (CLL) is currently undergoing rapid change. Increasingly, chemoimmunotherapy, which has been commonly used in the past, is being replaced by more targeted treatments. In…
View Post 3 min This content is machine translated Type 2 diabetes: insulin therapy - quo vadis? Basic insulin with once-weekly injection convinces An ultra-long-acting insulin analogue that only needs to be injected once a week is currently in development. The results of the clinical studies to date are promising. Insulin Icodec has…
View Post 6 min This content is machine translated Inflammatory dermatoses Acne and rosacea – current trends at a glance As with other skin diseases, research into the role of the microbiome and immunological factors is a current focus of research efforts in acne and rosacea. Since both are multifactorial…
