This content is machine translated Myelofibrosis Treatment in transition With the introduction of the Janus kinase (JAK) inhibitor ruxolitinib, therapy for myelofibrosis has changed dramatically in recent years. Nevertheless, further innovation is needed, especially in the second line. Promising…
View Post 5 min This content is machine translated Gastroesophageal reflux disease (GERD) Alginate as an as-needed add-on therapy increases patient satisfaction The standard therapy for treating all manifestations of reflux disease is proton pump inhibitors (PPI). Despite a high success rate, there are occasional patients with an insufficient response to therapy.…
View Post 4 min This content is machine translated Acute generalized exanthematous pustulosis (AGEP). Not just a T cell-mediated disease? Immunopathological studies have shown that not only T cells play a role in drug reactions, especially in AGEP, but also IL36 cytokines and other mediators are involved. These findings are…
View Post 3 min This content is machine translated SGLT2 inhibitors Cardioprotective effect proven and found to be good – a statement One of the serious long-term consequences of diabetes mellitus is cardiovascular disease. Heart failure, in particular, is common in patients who have had diabetes for a long time. Recent study…
View Post 3 min This content is machine translated Angina pectoris Antianginal therapy shows no long-term benefit for prophylaxis Angina may persist or recur despite successful revascularization with percutaneous coronary intervention. In these cases, antianginal treatment is supplemented. To demonstrate the effectiveness of this approach, a clinical trial was…
View Post 2 min This content is machine translated Acne vulgaris Low vitamin D levels in acne patients Vitamin D modulates immune functions through effects on the innate and acquired immune systems and plays a role in various dermatological diseases. In a recently published study, significantly decreased vitamin…
View Post 3 min This content is machine translated Diabetes Management Type 1 diabetics benefit from additive oral therapy Type 1 diabetics with obesity in whom insulin therapy alone is insufficient for glycemic control may additionally benefit from oral treatment with an SGLT2 inhibitor. Recent study results show good…
View Post 3 min This content is machine translated Breast Cancer News from the world of HER2-targeted treatment options Breast carcinoma is the most common malignant tumor in women. The prognosis of patients is determined primarily by the stage and biology of the disease. Innovative therapeutics and new treatment…
View Post 12 min This content is machine translated Venous thromboembolism Risks associated with hormone therapy Venous thromboembolism (VTE) is the third most common cardiovascular disease in Central Europe. They manifest as deep vein thrombosis in about two-thirds of cases and with symptoms of pulmonary embolism… CME-Test
View Post 2 min This content is machine translated Hypoxemia New insights into treatment with oxygen in intensive care medicine The New England Journal of Medicine (NEJM) recently published the large-scale multinational study “Handling Oxygenation Targets in the Intensive Care Unit” (HOT-ICU). Under the direction of Aalborg University Hospital, the…
View Post 2 min This content is machine translated REMAP-CAP Study Group COVID-19: New treatment recommendations in intensive care units. In an international collaboration, the REMAP-CAP study group is testing known agents in the treatment of COVID-19. Their results, now published in the New England Journal of Medicine, demonstrate the…
