This content is machine translated Friedreich's ataxia Loss of orientation in the cerebellum Spinocerebellar ataxias represent a large group of rare, progressive neurodegenerative diseases that affect the cerebellum and its connections and predominantly manifest themselves in a cerebellar syndrome. In addition to progressive...…
View Post 6 min This content is machine translated Subtyping as the key to precision medicine Molecular diversity of the PDAC Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive tumors of all. The five-year survival rate is still in the single digits. In recent years, however, there has been...…
View Post 4 min This content is machine translated Multiple sclerosis Vitamin D as an adjuvant in multiple sclerosis: statistical success and clinical limitations Various risk factors are involved in the pathogenesis of multiple sclerosis, with vitamin D deficiency being associated with an increased risk of MS since the 1970s. Disease-modifying therapies aim to...…
View Post 5 min This content is machine translated Artificial intelligence for COPD A new era of personalized treatment Chronic obstructive pulmonary disease (COPD) remains one of the leading causes of morbidity and mortality worldwide. The development of artificial intelligence (AI) has led to new ways of effectively treating...…
View Post 3 min This content is machine translated Multiple sclerosis Spirulina as adjuvant therapy? Reduction of cytokines and inflammation Disease-modifying therapies reduce relapse rates in multiple sclerosis. However, they often only incompletely address the aspects of oxidative stress and long-term neurodegeneration. Spirulina, a microalgae, is known for its strong...…
View Post 2 min This content is machine translated IBD and SARS-CoV-2 Vulnerable at the mercy of others While COVID-19 mRNA vaccines induce a robust systemic immune response in patients with inflammatory bowel disease (IBD), little is known about their efficacy in the mucosal immune system. Researchers have...…
View Post 5 min This content is machine translated Case Report 53-year-old female patient with palmoplantar keratoderma Palmoplantar keratoderma is characterized by excessive epidermal thickening of the skin on the palms and/or plantar surfaces of the feet and can be hereditary or acquired. The spectrum of possible...…
View Post 11 min This content is machine translated Incontinence Fecal incontinence from the perspective of gastroenterology Fecal incontinence is a medical problem that significantly impairs the quality of life of those affected, but often remains undiagnosed and untreated due to the sufferer’s sense of shame. It...… CME-Test
View Post 12 min This content is machine translated HER2-positive breast cancer ENPP1 as a biomarker for poor prognosis and early detection of brain metastases Around 15-20% of all breast cancer cases are HER2-positive, which is a subtype with an aggressive course and an increased tendency to metastasize to the brain. A new study now...…
View Post 6 min This content is machine translated Update 2025 Hypercholesterolemia The past 18 months have noticeably shifted the LDL-lowering landscape: An ESC/EAS-Focused Update 2025 sharpens the indication thresholds, real-world data confirm the benefit of early combinations after myocardial infarction, bempedoic...…
View Post 8 min This content is machine translated GPP: from molecular principles to targeted therapy Therapeutic rationale for targeted IL-36 receptor inhibition The progress in the diagnosis and treatment of generalized pustular psoriasis (GPP) is remarkable. GPP has developed into a clearly defined, independent, IL-36-mediated autoinflammatory disease. Today, the high chronic disease...…
