This content is machine translated Ulcerative colitis Rgs14 protein can worsen the severity Rgs14 is a protein that acts as a regulator of G-protein signaling pathways by accelerating the GTPase activity of G-protein alpha subunits and thereby converting them to their inactive GDP-bound...…
View Post 8 min This content is machine translated Mastocytosis Innovative pathogenesis-based therapeutic approaches in the pipeline The treatment of mastocytosis has undergone a paradigm shift in recent years. A deeper molecular understanding of the disease has paved the way from a purely symptomatic to a targeted,...…
View Post 14 min This content is machine translated Participation of the patient Adherence in psychiatry Adherence problems in psychiatry arise due to illness-related restrictions, side effects and psychosocial, economic and cultural burdens. Low insight into the illness, affective instability and cognitive deficits make adherence to...… CME-Test
View Post 6 min This content is machine translated Lipid management: ESC/EAS guideline update 2025 New recommendations on CVD risk classification, lipid lowering in statin intolerance and hoFH The European Society of Cardiology (ESC) and European Atherosclerosis Society (EAS) guideline update on the management of dyslipidemia continues to focus largely on how best to manage lipid levels to...…
View Post 5 min This content is machine translated Chronically active MS lesions New paradigm in the diagnosis and treatment of multiple sclerosis Focal chronic active lesions (CALs) play a key role in the increase in MS disability, which is due to smoldering neuroinflammation in the central nervous system. This inflammation, often behind...…
View Post 14 min This content is machine translated Participation of the patient Adherence in psychiatry Adherence problems in psychiatry arise due to illness-related restrictions, side effects and psychosocial, economic and cultural burdens. Low insight into the illness, affective instability and cognitive deficits make adherence to...… CME-Test
View Post 5 min This content is machine translated Eosinophilic esophagitis EoE rarely occurs in isolation Eosinophilic oesophagitis (EoE) is still inadequately treated in terms of its association with other type 2 inflammatory diseases (T2). Italian researchers attempted to close this gap. Their conclusion: In EoE...…
View Post 8 min This content is machine translated Lung cancer with EGFR mutation New perspectives in first-line therapy At this year’s IASLC World Conference on Lung Cancer (WCLC 2025) in Barcelona, a poster on the FLAURA2 study was presented, which presented new data on combination therapy with osimertinib...…
View Post 3 min This content is machine translated Ginkgo biloba extract in the Alzheimer's mouse model Effects on disease-associated microglia subpopulations During the progression of Alzheimer’s disease, microglial cells located in the vicinity of plaques become overactivated and release cytotoxic mediators such as TNFα. In an animal study published in 2025,...…
View Post 3 min This content is machine translated "Patients W.A.I.T Indicator" Access to medicines – how does Switzerland compare across Europe? According to a major international study, Switzerland has once again fallen behind other European countries in terms of access to new innovative medicines – from sixth to seventh place. Particularly...…
View Post 5 min This content is machine translated Adherence in severe or poorly controlled asthma Digital monitoring with potential for greater treatment adherence Despite proven pharmacological strategies for the treatment of asthma, lack of adherence to inhaled therapy remains a major problem, particularly in patients requiring a triple combination. Digital tools have shown...…
