Changing therapy landscape – a lot is happening

Inflamed, itchy and sometimes painful skin lesions on the hands can significantly impair quality of life. If chronic hand eczema proves to be refractory to topical treatment, systemic therapy is called for. In addition to alitretinoin, the topical JAK inhibitor delgocitinib is now available in Switzerland as a further systemic therapy option and several representatives of JAK-i and biologics are being researched.