Endotyping as a basis for targeted treatment

In particular, chronic rhinosinusitis with polyposis nasi (CRSwNP) is often associated with high levels of distress and personalized therapeutic strategies are required. Improved understanding of the immunological and inflammatory genesis of nasal polyps has now made it possible not only to remove them surgically, but also to intervene directly in inflammatory processes based on endotyping. Here, biologics for severe cases of CRSwNP play an increasingly important role.