Medizinonline Medizinonline
  • News
    • News
    • Market & Medicine
  • Patients
    • Disease patterns
    • Diagnostics
    • Therapy
  • Partner Content
    • Dermatology
      • Atopic dermatitis and psoriasis news
      • Dermatology News
    • Diabetes
      • Dia-Month Club – Type 2 Diabetes
      • Diabetes in Motion
      • Diabetes Podcasts
    • Gastroenterology
      • IBD matters
      • Forum Gastroenterology
      • Ozanimod: ulcerative colitis
      • Reflux Update
    • Immunology
      • Primary immunodeficiency – exchange of experience
    • Vaccinate
      • Herpes zoster
    • Infektiologie
    • Neurology
      • EXPERT ULTRASONIC: Introduction to ultrasound-guided injection
      • MS News
      • MS Therapy in Transition
    • Oncology
      • Swiss Oncology in motion
    • Orthopedics
      • Osteoporosis in motion
    • Phytotherapie
    • Practice Management
      • Aargau Cantonal Bank
      • Claraspital
    • Psychiatry
      • Geriatric Psychiatry
    • Rheumatology
  • Departments
    • Allergology and clinical immunology
    • General Internal Medicine
    • Anesthesiology
    • Angiology
    • Surgery
    • Dermatology and venereology
    • Endocrinology and Diabetology
    • Nutrition
    • Gastroenterology and Hepatology
    • Genetics
    • Geriatrics
    • Gynecology
    • Hematology
    • Infectiology
    • Cardiology
    • Nephrology
    • Neurology
    • Emergency and intensive care medicine
    • Nuclear Medicine
    • Oncology
    • Ophthalmology
    • ORL
    • Orthopedics
    • Pediatrics
    • Pharmacology and toxicology
    • Pharmaceutical medicine
    • Phlebology
    • Physical medicine and rehabilitation
    • Pneumology
    • Prevention and health care
    • Psychiatry and psychotherapy
    • Radiology
    • Forensic Medicine
    • Rheumatology
    • Sports Medicine
    • Traumatology and trauma surgery
    • Tropical and travel medicine
    • Urology
    • Dentistry
  • CME & Congresses
    • CME continuing education
    • Congress Reports
    • Congress calendar
  • Practice
    • Noctimed
    • Practice Management
    • Jobs
    • Interviews
  • Log In
  • Register
  • My account
  • Contact
  • English
    • Deutsch
    • Français
    • Italiano
    • Português
    • Español
  • Publications
  • Contact
  • Deutsch
  • English
  • Français
  • Italiano
  • Português
  • Español
Subscribe
Medizinonline Medizinonline
Medizinonline Medizinonline
  • News
    • News
    • Market & Medicine
  • Patienten
    • Krankheitsbilder
    • Diagnostik
    • Therapie
  • Partner Content
    • Dermatology
      • Atopic dermatitis and psoriasis news
      • Dermatology News
    • Diabetes
      • Dia-Month Club – Type 2 Diabetes
      • Diabetes in Motion
      • Diabetes Podcasts
    • Gastroenterology
      • IBD matters
      • Forum Gastroenterology
      • Ozanimod: ulcerative colitis
      • Reflux Update
    • Immunology
      • Primary immunodeficiency – exchange of experience
    • Vaccinate
      • Herpes zoster
    • Infektiologie
    • Neurology
      • EXPERT ULTRASONIC: Introduction to ultrasound-guided injection
      • MS News
      • MS Therapy in Transition
    • Oncology
      • Swiss Oncology in motion
    • Orthopedics
      • Osteoporosis in motion
    • Phytotherapie
    • Practice Management
      • Aargau Cantonal Bank
      • Claraspital
    • Psychiatry
      • Geriatric Psychiatry
    • Rheumatology
  • Departments
    • Fachbereiche 1-13
      • Allergology and clinical immunology
      • General Internal Medicine
      • Anesthesiology
      • Angiology
      • Surgery
      • Dermatology and venereology
      • Endocrinology and Diabetology
      • Nutrition
      • Gastroenterology and Hepatology
      • Genetics
      • Geriatrics
      • Gynecology
      • Hematology
    • Fachbereiche 14-26
      • Infectiology
      • Cardiology
      • Nephrology
      • Neurology
      • Emergency and intensive care medicine
      • Nuclear Medicine
      • Oncology
      • Ophthalmology
      • ORL
      • Orthopedics
      • Pediatrics
      • Pharmacology and toxicology
      • Pharmaceutical medicine
    • Fachbereiche 26-38
      • Phlebology
      • Physical medicine and rehabilitation
      • Phytotherapy
      • Pneumology
      • Prevention and health care
      • Psychiatry and psychotherapy
      • Radiology
      • Forensic Medicine
      • Rheumatology
      • Sports Medicine
      • Traumatology and trauma surgery
      • Tropical and travel medicine
      • Urology
      • Dentistry
  • CME & Congresses
    • CME continuing education
    • Congress Reports
    • Congress calendar
  • Practice
    • Noctimed
    • Practice Management
    • Jobs
    • Interviews
Login

Sie haben noch keinen Account? Registrieren

  • Migraine

Escaping the grip of pain – effective therapy makes it possible

    • Congress Reports
    • General Internal Medicine
    • Neurology
    • RX
  • 2 minute read

Migraine is based on a complex pathophysiology, which could only be detected gradually. According to current knowledge, a genetic predisposition, certain triggers, stress or overwork can trigger the recurring headache attacks. Meanwhile, many treatment managements are based on the key mechanisms of the disease and can lead to effective outcomes.

Science has now been able to debunk migraine as a neuronal disease rather than a purely vascular one. This is because both peripheral and central sensitization processes are involved in their development. In Switzerland, about one million of the population suffers from the recurring headache attacks. The burden of disease is high because it is not only the pain that is burdensome. They often also entail loss of function, as the pain increases with physical activity. In addition, they are often accompanied by loss of appetite, nausea with or without vomiting, sensitivity to noise, light and smell. It is hardly surprising that migraine has been ranked by the WHO as one of the leading causes of years of life lost worldwide.

In drug treatment, a distinction is made between acute therapy and prophylaxis. Both are meant to be reliably effective and have few side effects. Acute therapy is used to quickly reduce or stop headaches, eliminate accompanying symptoms and restore function. Prophylaxis is indicated, especially in severely affected patients, to reduce the frequency and intensity, increase the efficacy of acute medication, and achieve an increase in headache-free time. According to the S1 guideline on migraine attack therapy and prophylaxis of migraine, prophylaxis should be considered when the level of distress, reduction in quality of life, and risk of medication overuse are high.

Undersupply in view

However, according to recent surveys, the implementation of the recommendation still leaves room for improvement. Migraine is still frequently undiagnosed or diagnosed late, many patients accept it as fated, and prophylaxis has not yet been widely established. According to a survey, only about 50% of those affected could provide a corresponding diagnosis. Furthermore, of the migraine patients, although 98% were taking acute therapy, only 12.4% were receiving prophylaxis. But analyses show that just under 35% of those affected qualify for prophylactic treatment. The fact that care is so poor may be due in part to reservations about prophylactics on the part of patients and physicians, who fear many side effects, dependence, and high costs. But this need not be the case, as was made clear once again at the congress. Beta-blockers (e.g., propranolol, metoprolol), calcium antagonists (e.g., flunarizine), anticonvulsants (e.g., topiramate), antidepressants (e.g., amitriptyline), and onabotulinumtoxin A are recommended for episodic migraine of three attacks or more per month or chronic migraine. If these are not tolerated or do not show sufficient effect, monoclonal antibodies against CGRP (fremanezumab, galcanezumab) or the CGRP receptor (erenumab) can be used. They are considered to be particularly well tolerated and very effective. Not only can the number of migraine attacks be effectively reduced, but also their intensity.

Congress: Pain Congress 2021

 

InFo NEUROLOGY & PSYCHIATRY 2021; 19(6): 28 (published 1/12/21, ahead of print).

Autoren
  • Leoni Burggraf
Publikation
  • InFo NEUROLOGIE & PSYCHIATRIE
Related Topics
  • migraine
  • Pain Congress
Previous Article
  • "Digital Trends Survey 2021"

Digitization of medical applications

  • Education
  • General Internal Medicine
  • Prevention and health care
  • RX
View Post
Next Article
  • Ovarian tumors

Therapy Update

  • Congress Reports
  • Gynecology
  • Oncology
  • RX
  • Studies
View Post
You May Also Like
View Post
  • 5 min
  • New findings on known forms of therapy

Fatigue syndrome as a leading symptom in multiple sclerosis

    • Education
    • Neurology
    • Pharmacology and toxicology
    • RX
    • Studies
View Post
  • 5 min
  • Asthma in adults

When do pneumology specialists come into play?

    • RX
View Post
  • 10 min
  • Cutaneous lupus erythematosus

From diagnostic workup to successful treatment

    • Congress Reports
    • Dermatology and venereology
    • RX
    • Studies
View Post
  • 4 min
  • Guideline update

Dietary recommendations for Crohn’s disease and colitis

    • Education
    • Gastroenterology and Hepatology
    • General Internal Medicine
    • Nutrition
    • RX
    • Studies
View Post
  • 4 min
  • Circadian rhythm during Ramadan

Disturbed sleep patterns lead to metabolic stress

    • Education
    • Endocrinology and Diabetology
    • General Internal Medicine
    • Nutrition
    • RX
    • Studies
View Post
  • 6 min
  • Case Report

Breast cancer metastases in the bladder

    • Cases
    • Education
    • Gynecology
    • Oncology
    • RX
    • Urology
View Post
  • 11 min
  • Findings from the ALS Symposium 2024 in Montreal

Current and future approaches in the treatment of amyotrophic lateral sclerosis (ALS)

    • Congress Reports
    • Interviews
    • Neurology
    • RX
    • Studies
View Post
  • 8 min
  • Efficacy, mechanism of action and clinical effects

Garlic and high blood pressure

    • Cardiology
    • Education
    • General Internal Medicine
    • Pharmaceutical medicine
    • Phytotherapy
    • RX
    • Studies
Top Partner Content
  • Forum Gastroenterology

    Zum Thema
  • Herpes zoster

    Zum Thema
  • Dermatology News

    Zum Thema
Top CME content
  • 1
    Patience, knowledge and persistence in therapy
  • 2
    Sarcopenia and malnutrition in the context of pneumological rehabilitation
  • 3
    Medical and psychosocial perspectives
  • 4
    New nomenclature for non-alcoholic fatty liver disease
  • 5
    Examinations and considerations before therapy

Newsletter

Sign up and stay up to date

Subscribe
Medizinonline
  • Contact
  • General terms and conditions
  • Imprint

Input your search keywords and press Enter.