Guillain-Barré syndrome with a fulminant course

A 38-year-old male patient experienced a transient loss of all brainstem reflexes as part of an unusual course of Guillain-Barré syndrome, which, despite preserved cortical functions, resembled a coma or brain death. As treatment progressed, his condition gradually improved. This demonstrates that early diagnosis, the exclusion of central causes, and timely immunotherapy can lead to significant neurological recovery even in the most severe cases of Guillain-Barré syndrome.