Medizinonline Medizinonline
  • News
    • News
    • Market & Medicine
  • Patients
    • Disease patterns
    • Diagnostics
    • Therapy
  • Partner Content
    • Dermatology
      • Atopic dermatitis and psoriasis news
      • Dermatology News
    • Diabetes
      • Dia-Month Club – Type 2 Diabetes
      • Diabetes in Motion
      • Diabetes Podcasts
    • Gastroenterology
      • IBD matters
      • Forum Gastroenterology
      • Ozanimod: ulcerative colitis
      • Reflux Update
    • Immunology
      • Primary immunodeficiency – exchange of experience
    • Vaccinate
      • Herpes zoster
    • Infektiologie
    • Neurology
      • EXPERT ULTRASONIC: Introduction to ultrasound-guided injection
      • MS News
      • MS Therapy in Transition
    • Oncology
      • Swiss Oncology in motion
    • Orthopedics
      • Osteoporosis in motion
    • Phytotherapie
    • Practice Management
      • Aargau Cantonal Bank
      • Claraspital
    • Psychiatry
      • Geriatric Psychiatry
    • Rheumatology
  • Departments
    • Allergology and clinical immunology
    • General Internal Medicine
    • Anesthesiology
    • Angiology
    • Surgery
    • Dermatology and venereology
    • Endocrinology and Diabetology
    • Nutrition
    • Gastroenterology and Hepatology
    • Genetics
    • Geriatrics
    • Gynecology
    • Hematology
    • Infectiology
    • Cardiology
    • Nephrology
    • Neurology
    • Emergency and intensive care medicine
    • Nuclear Medicine
    • Oncology
    • Ophthalmology
    • ORL
    • Orthopedics
    • Pediatrics
    • Pharmacology and toxicology
    • Pharmaceutical medicine
    • Phlebology
    • Physical medicine and rehabilitation
    • Pneumology
    • Prevention and health care
    • Psychiatry and psychotherapy
    • Radiology
    • Forensic Medicine
    • Rheumatology
    • Sports Medicine
    • Traumatology and trauma surgery
    • Tropical and travel medicine
    • Urology
    • Dentistry
  • CME & Congresses
    • CME continuing education
    • Congress Reports
    • Congress calendar
  • Practice
    • Noctimed
    • Practice Management
    • Jobs
    • Interviews
  • Log In
  • Register
  • My account
  • Contact
  • English
    • Deutsch
    • Français
    • Italiano
    • Português
    • Español
  • Publications
  • Contact
  • Deutsch
  • English
  • Français
  • Italiano
  • Português
  • Español
Subscribe
Medizinonline Medizinonline
Medizinonline Medizinonline
  • News
    • News
    • Market & Medicine
  • Patienten
    • Krankheitsbilder
    • Diagnostik
    • Therapie
  • Partner Content
    • Dermatology
      • Atopic dermatitis and psoriasis news
      • Dermatology News
    • Diabetes
      • Dia-Month Club – Type 2 Diabetes
      • Diabetes in Motion
      • Diabetes Podcasts
    • Gastroenterology
      • IBD matters
      • Forum Gastroenterology
      • Ozanimod: ulcerative colitis
      • Reflux Update
    • Immunology
      • Primary immunodeficiency – exchange of experience
    • Vaccinate
      • Herpes zoster
    • Infektiologie
    • Neurology
      • EXPERT ULTRASONIC: Introduction to ultrasound-guided injection
      • MS News
      • MS Therapy in Transition
    • Oncology
      • Swiss Oncology in motion
    • Orthopedics
      • Osteoporosis in motion
    • Phytotherapie
    • Practice Management
      • Aargau Cantonal Bank
      • Claraspital
    • Psychiatry
      • Geriatric Psychiatry
    • Rheumatology
  • Departments
    • Fachbereiche 1-13
      • Allergology and clinical immunology
      • General Internal Medicine
      • Anesthesiology
      • Angiology
      • Surgery
      • Dermatology and venereology
      • Endocrinology and Diabetology
      • Nutrition
      • Gastroenterology and Hepatology
      • Genetics
      • Geriatrics
      • Gynecology
      • Hematology
    • Fachbereiche 14-26
      • Infectiology
      • Cardiology
      • Nephrology
      • Neurology
      • Emergency and intensive care medicine
      • Nuclear Medicine
      • Oncology
      • Ophthalmology
      • ORL
      • Orthopedics
      • Pediatrics
      • Pharmacology and toxicology
      • Pharmaceutical medicine
    • Fachbereiche 26-38
      • Phlebology
      • Physical medicine and rehabilitation
      • Phytotherapy
      • Pneumology
      • Prevention and health care
      • Psychiatry and psychotherapy
      • Radiology
      • Forensic Medicine
      • Rheumatology
      • Sports Medicine
      • Traumatology and trauma surgery
      • Tropical and travel medicine
      • Urology
      • Dentistry
  • CME & Congresses
    • CME continuing education
    • Congress Reports
    • Congress calendar
  • Practice
    • Noctimed
    • Practice Management
    • Jobs
    • Interviews
Login

Sie haben noch keinen Account? Registrieren

  • Gastroesophageal reflux disease

Better symptom control and patient satisfaction with add-on therapy

    • Gastroenterology and Hepatology
    • General Internal Medicine
    • Market & Medicine
    • RX
    • Studies
  • 2 minute read

PPI therapy for GERD does not result in adequate symptom control in some patients. Add-on treatment could help.

Gastroesophageal reflux disease (GERD) affects up to 20% of all people in Western industrialized countries. Guideline-guided treatment with PPI is particularly aimed at good symptom control, cure of reflux esophagitis, and prevention of complications. However, even with PPI therapy, residual symptoms persist in 20% of GERD patients.

A 14-day prospective observational study now demonstrated a therapeutic benefit of add-on therapy with alginate. The herbal substance acts physically by forming a protective layer on the acid pocket in conjunction with stomach acid; this is formed in the upper stomach area after meals and serves as a reservoir for acid reflux. It works within five minutes, lasts up to four hours and may also be taken during pregnancy.

Add-on alginate recommended

The study included 153 GERD patients who were 57 years old on average, had suffered from chronic GERD for eight years, and had been on continuous PPI therapy for six. Depending on their needs, the study participants took an average of three sachets per day. Compared with baseline, this add-on therapy was reflected in an increase in treatment satisfaction by at least one level of the five-point Likert scale in 72% after fourteen days. 23% were similarly satisfied to when they started add-on therapy, while 5% reported decreased satisfaction. Furthermore, it was shown that 81% of patients with a GERDQ score >8 benefited from the additional administration of alginate.

The substance also had an influence on how frequently typical reflux symptoms occurred. Whereas 56% of patients had previously complained of heartburn on 4-7 days, only 19% did so shortly before the study was completed. Regurgitation and sleep disturbances occurred two to four times less frequently. In light of these findings, the study investigator believes that add-on therapy with alginate, in addition to continuous therapy with PPI, is a reasonable adjunct to achieve adequate symptom control and a higher quality of life for patients.

>Tip: If you want to learn more about facets of GERD, you can read about various reflux cases at Reflux Update.

HAUSARZT PRAXIS 2019; 14(5): 8

Publikation
  • HAUSARZT PRAXIS
Related Topics
  • GERD
  • Heartburn
  • PPI
  • Reflux
Previous Article
  • Fit in the head with ginkgo

Six-week study documents increase in memory performance

  • General Internal Medicine
  • News
  • Pharmaceutical medicine
  • RX
  • Studies
View Post
Next Article
  • Burnout among medical professionals

Family physicians are particularly at risk

  • General Internal Medicine
  • Interviews
  • Prevention and health care
  • RX
View Post
You May Also Like
View Post
  • 6 min
  • Treatment of vitiligo

Focus on patient perspective and disease activity

    • Congress Reports
    • Dermatology and venereology
    • Pharmacology and toxicology
    • RX
    • Studies
View Post
  • 5 min
  • Vaccine-preventable respiratory diseases

RSV and pneumococci: recommendations for risk groups

    • Congress Reports
    • General Internal Medicine
    • Infectiology
    • Pediatrics
    • Pneumology
    • Prevention and health care
    • RX
    • Studies
View Post
  • 5 min
  • Circadian rhythm in asthma

Chronotherapy can improve control

    • Allergology and clinical immunology
    • General Internal Medicine
    • Pneumology
    • RX
    • Studies
View Post
  • 6 min
  • Update on diagnostics, risk stratification and therapy

Acute myeloid leukemia 2025

    • Education
    • Hematology
    • Oncology
    • RX
    • Studies
View Post
  • 4 min
  • New practice guideline for fibromyalgia syndrome

Good times, bad times

    • Congress Reports
    • General Internal Medicine
    • Neurology
    • Pharmacology and toxicology
    • Physical medicine and rehabilitation
    • Rheumatology
    • RX
    • Sports Medicine
    • Studies
View Post
  • 5 min
  • Findings from the TRACK-FA study

Neuroimaging biomarkers in Friedreich’s ataxia

    • Genetics
    • Neurology
    • Pediatrics
    • RX
    • Studies
View Post
  • 12 min
  • Doing sport without fear or risk

Doing sport without fear or risk

    • CME continuing education
    • Endocrinology and Diabetology
    • Pediatrics
    • RX
    • Sports Medicine
View Post
  • 8 min
  • Chronic inducible urticaria

What has stayed the same, what has changed?

    • Allergology and clinical immunology
    • Congress Reports
    • Dermatology and venereology
    • RX
    • Studies
Top Partner Content
  • Forum Gastroenterology

    Zum Thema
  • Herpes zoster

    Zum Thema
Top CME content
  • 1
    Doing sport without fear or risk
  • 2
    UV protection and skin cancer screening – Update 2025
  • 3
    Rare malignancy from a dermatological perspective
  • 4
    Yellow nail and Swyer-James syndrome
  • 5
    Diagnostic indications

Newsletter

Sign up and stay up to date

Subscribe
Medizinonline
  • Contact
  • General terms and conditions
  • Imprint

Input your search keywords and press Enter.