This content is machine translated SGLT2 inhibitors and glucocorticoids Protective effect on kidney function is maintained SGLT2 inhibitors have been shown in randomized trials to be effective in improving cardiovascular and renal outcomes. However, the populations in these studies were carefully selected, usually excluding patients under...…
View Post 6 min This content is machine translated Treatment of pancreatitis: current study data How can the risk-benefit profile be improved? Acute pancreatitis is a life-threatening complication in patients with familial chylomicronemia syndrome. With olezarsen and plozasiran, two innovative drug candidates have been developed for which promising Phase III data are...…
View Post 12 min This content is machine translated Multiple myeloma DREAMM-8: Key study in the development of BCMA therapy up to DREAMM-14 The DREAMM-8 data presented at this year’s ASCO provided robust evidence of the efficacy and tolerability of the BPd combination (belantamab mafodotin, pomalidomide and dexamethasone) for the treatment of recurrent...…
View Post 6 min This content is machine translated Cardiovascular risk Bad news for young men with T2D Cardiovascular disease ( CVD) remains the leading cause of death and disease worldwide, and people with type 1 or type 2 diabetes are at higher risk than the general population....…
View Post 5 min This content is machine translated Antithymocyte globulin in children with T1D Old medicine, new hope The well-known immunomodulatory drug antithymocyte globulin (ATG) can effectively inhibit the progression of type 1 diabetes (T1D) in young patients at low doses, while at the same time having a...…
View Post 3 min This content is machine translated Phimosis and penile cancer under SGLT2i Increased risk for men with T2D In recent years, sodium-glucose cotransporter 2 inhibitors (SGLT2i) have been widely used in the treatment of type 2 diabetes, as they not only provide improved glycemic control, but also offer...…
View Post 8 min This content is machine translated Atopic dermatitis From skin barrier disorder to atopic march? An early onset and persistent course of atopic dermatitis are the strongest predictors of atopic march. New diagnostic methods such as electrical impedance spectroscopy and the analysis of biomarkers from...…
View Post 3 min This content is machine translated Development of a quintuple agonist New strategy in the fight against obesity and T2D The treatment of obesity and type 2 diabetes is increasingly shifting to newer incretin drugs, including GLP1 receptor agonists (single agonists such as semaglutide) and GIP- and GLP1-RA (dual agonists...…
View Post 3 min This content is machine translated Adherence of GLP1-RA Half of patients discontinue treatment within a year GLP1 receptor agonists have revolutionized the treatment of obesity, but their effectiveness depends on long-term and continuous use. However, data from Danish health registries presented at EASD 2025 show that...…
View Post 6 min This content is machine translated Obesity in the family practice Aim for realistic goals and avoid apportioning blame Morbid obesity is a significant health risk factor and its prevalence has increased in many industrialized countries in recent years. The principles of weight reduction have hardly changed over the...…
View Post 2 min This content is machine translated Ulcerative colitis Rgs14 protein can worsen the severity Rgs14 is a protein that acts as a regulator of G-protein signaling pathways by accelerating the GTPase activity of G-protein alpha subunits and thereby converting them to their inactive GDP-bound...…
