This content is machine translated MASH and heart health The underestimated cardiovascular threat Metabolic-associated steatohepatitis (MASH) was long considered a purely hepatic problem. Today, data from large clinical trials and registries clearly show that cardiovascular disease is the most common cause of death...…
View Post 10 min This content is machine translated Irritable Bowel Syndrome Functional disorder of gut-brain interaction – a biopsychosocial concept According to recent findings, irritable bowel syndrome is one of the disorders of the gut-brain axis. Stress, intestinal permeability and inflammatory processes play an important role here. In clinical practice,...…
View Post 9 min This content is machine translated Polycystic ovary syndrome 2025/2026 New pathophysiology, updated diagnostics and the age of incretin mimetics With a prevalence of 8-13%, polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age – and yet up to 70% of those affected remain...…
View Post 5 min This content is machine translated Case study Autosomal recessive polycystic kidney disease: atypical phenotype In a 5-year-old boy with renal ultrasound findings typical of autosomal recessive polycystic kidney disease (ARPKD), numerous large liver cysts were found – atypical for this disease. Genetic analyses revealed...…
View Post 4 min This content is machine translated Pancreatic Cancer Innovative early detection with a focus on liquid biopsy and AI The early detection of pancreatic cancer is developing rapidly: new multimodal approaches combine imaging with molecular biomarkers such as ctDNA, methylation signatures, fragmentomics and proteomics. For high-risk groups in particular,...…
View Post 7 min This content is machine translated Clostridioides difficile infection: specific therapy Importance of vancomycin and fidaxomicin has increased C. difficile infection (CDI) is the most common pathogen-related cause of nosocomial diarrhea, but can also occur in outpatients if risk factors are present. Due to the associated morbidity and...…
View Post 6 min This content is machine translated MASLD often goes unnoticed and is underestimated Think tank for improving the supply situation Metabolic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease (NAFLD), can lead to serious complications. Non-invasive diagnostics and AI-supported screening have the potential to facilitate early detection in...…
View Post 4 min This content is machine translated Case series Mast cell activation syndrome (MCAS) MCAS is now understood as an independent disorder in contrast to systemic or cutaneous mastocytosis. The signs and symptoms can affect the skin, the gastrointestinal tract and the cardiovascular system,...…
View Post 9 min This content is machine translated Irritable Bowel Syndrome “Best practice” recommendations for step-by-step clarification and stage-adapted therapy The diagnosis of irritable bowel syndrome (IBS) is based on the Rome IV criteria for functional gastrointestinal disorders. The main symptoms are abdominal pain and altered bowel habits, but patients...…
View Post 4 min This content is machine translated Study report Sphingolipid profile in early-stage primary biliary cholangitis Using ultra-high performance liquid chromatography coupled with tandem mass spectrometry (UHPLC-MS/MS), a Polish research team discovered interesting new insights into the changes in sphingolipid metabolism in patients with early-stage primary...…
View Post 3 min This content is machine translated Risk of osteoporosis in autoimmune liver diseases Always determine bone density in PBC, PSC and AIH Studies show that primary biliary cholangitis (PBC), primary sclerosing cholangitis (PSC) and autoimmune hepatitis (AIH) are associated with a significantly increased risk of developing osteopenia or osteoporosis. For this reason,...…
