This content is machine translated Friedreich's ataxia Interim analyses of the PROFA study show “Unmet needs” The PROFA study focuses, among other things, on patient-reported psychosocial effects of Friedreich’s ataxia (FRDA) at different stages of the disease. The study comprises a cohort of FRDA patients in...…
View Post 5 min This content is machine translated Ataxias Friedreich’s ataxia: when the energy metabolism attacks the nervous system Energy deficiency instead of pure oxidative stress: New data show that in Friedreich’s ataxia, disturbances in fatty acid and ketone body metabolism in particular contribute to selective neurodegeneration. The article...…
View Post 7 min This content is machine translated Restless legs syndrome in children Relationship between restless legs syndrome and growing pains When restless legs syndrome is actually behind “growing pains”. Which laboratory values should be specifically clarified. A review shows considerable overlap between the two disorders in childhood. Serotonin dysfunction, iron...…
View Post 7 min This content is machine translated Between hope and evidence gaps Tinnitus and phytotherapy Tinnitus is a highly prevalent symptom with a considerable impact on quality of life; randomized studies have not yet shown any clearly effective standard pharmacological therapy. Guidelines primarily recommend educational,...…
View Post 6 min This content is machine translated Pediatric epilepsy Diazepam nasal spray for infants Fast and socially uncomplicated treatment of seizure clusters in infants. Intranasal diazepam shows reliable drug absorption and good tolerability. A phase 1/2a study in 2- to 5-year-old epilepsy patients confirms...…
View Post 4 min This content is machine translated Amyotrophic lateral sclerosis and nutrition Calorie optimization in ALS through digital intervention How digital nutrition programs can slow down weight loss in ALS. Why relatives are crucial for the success of therapy. A web-based intervention for calorie optimization proved to be easy...…
View Post 14 min This content is machine translated "Forgotten axis" between plant substances, gut and systemic health Microbiome and phytotherapy In recent years, the intestinal microbiome has developed from a marginal phenomenon to a central topic in immunology, metabolic medicine, neuroscience and oncology. Dysbiosis is associated with obesity, type 2...…
View Post 25 min This content is machine translated Neuroenhancement Can you swallow intelligence? Relevant substance classes times for healthy people What neuroenhancement really improves – and what only works subjectively better. Those who use cognitive performance-enhancing substances particularly frequently. Between Ritalin, Modafinil and coffee, the line between therapy and optimization...… CME-Test
View Post 9 min This content is machine translated Microbiome, inflammaging and affective/cognitive health Gut-brain axis in old age As we age, the composition and function of the gut microbiome, the integrity of the intestinal barrier and systemic immune regulation change. These changes are closely linked to the concept...…
View Post 3 min This content is machine translated Case report: Hiccups after ketoacidosis Nebulized lidocaine brings relief Persistent hiccups are a rare but distressing symptom that can significantly affect the quality of life of patients with diabetic ketoacidosis (DKA). In one clinical case, treatment with inhaled nebulized...…
View Post 7 min This content is machine translated Dizziness as a leading symptom: new consensus paper Current recommendations for handling in everyday practice Dizziness is one of the 20 most common causes of consultation in GP practices. Most causes of dizziness can already be clarified at the primary care level, but the broad...…
