This content is machine translated Pathophysiology, clinical significance and therapeutic consequences Eosinophils in asthma For a long time, eosinophils were regarded as the central effector cells of asthma and were interpreted in the classical model as a direct damaging agent of the epithelium, as...…
View Post 12 min This content is machine translated Urothelial carcinoma Perioperative innovations and organ-preserving strategies Urothelial carcinoma is an aggressive tumor entity with high morbidity. In recent years, the perioperative treatment spectrum – particularly for muscle-invasive bladder cancer – has expanded significantly: Immune checkpoint inhibitors...…
View Post 14 min This content is machine translated Artificial intelligence Dr. ChatGPT: Large language models in everyday clinical practice With the public availability of ChatGPT 3.5 in fall 2022 at the latest, artificial intelligence in the sense of large language models (LLMs) is on everyone’s lips. However, it is...… CME-Test
View Post 3 min This content is machine translated GLA:D® program for back pain patients Fewer consultations and reduction in the use of painkillers In a quasi-experimental Danish study of patients with lower back pain, participation in a structured self-management program led to a sustained reduction in the number of visits to the doctor...…
View Post 5 min This content is machine translated Nutrition for type 2 diabetes Not such a great tuber The link between potato consumption and the risk of type 2 diabetes has long been debated. Although potatoes are a staple food worldwide, rich in starch and with a high...…
View Post 9 min This content is machine translated Microbiome, inflammaging and affective/cognitive health Gut-brain axis in old age As we age, the composition and function of the gut microbiome, the integrity of the intestinal barrier and systemic immune regulation change. These changes are closely linked to the concept...…
View Post 4 min This content is machine translated From symptom to diagnosis Abdominal pain – external hernias If the hernia can be seen from the outside or if the protrusion resulting from a hernia leads from the inside of the body towards the skin, it is referred...…
View Post 6 min This content is machine translated What biomarkers reveal about "biological youth" - and what not (yet) Epigenetic ageing In recent years, epigenetic clocks based on DNA methylation have evolved from research tools to widely used biomarkers of biological ageing. They correlate not only with chronological age, but also...…
View Post 10 min This content is machine translated Mechanisms, evidence and therapeutic consequences GLP-1 receptor agonists in cardiology GLP-1 receptor agonists (GLP-1RAs) have rapidly evolved from antidiabetic drugs to cardiometabolic therapies with clinically proven reductions in hard cardiovascular endpoints – and increasingly beyond the traditional diabetes population. The...…
View Post 6 min This content is machine translated MASLD/MASH Drug therapy options on the rise: spectacular evidence Over the last few decades, the incidence of steatotic liver disease has risen in parallel with the increase in obesity, diabetes and other metabolic diseases. It is recommended to screen...…
View Post 6 min This content is machine translated New ways of neuroregeneration CRISPR and artificial intelligence The combination of precise genome editing using CRISPR and AI-supported modeling of complex CNS damage marks a paradigm shift in neuroregeneration. Adaptive, closed therapy loops are designed to address multiple...…
