This content is machine translated Pathophysiology, cardiovascular consequences and metabolic interventions Obesity accelerates cardiovascular ageing Obesity and demographic ageing are two global megatrends that overlap in a particularly unfavorable way in the cardiovascular system. Both factors independently increase the risk of cardiovascular disease, but also...…
View Post 6 min This content is machine translated CKD: counteracting kidney progression and reducing the risk of CVD Targeted intervention through a multifactorial approach The Swiss Society of Nephrology (SGN) advocates targeted screening for defined risk groups. However, given the prevalence of chronic kidney disease (CKD) in primary care, it is hardly possible to...…
View Post 11 min This content is machine translated COPD therapy Drug therapy – Update 2025 Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory multisystem disease caused primarily by inhaled noxious substances in combination with environmental factors and genetic predispositions. The presence of such a...… CME-Test
View Post 7 min This content is machine translated Atrial fibrillation: interdisciplinary effort is crucial Managing risk factors and comorbidities in addition to rhythm control The previously used “ABC” scheme was replaced by the more comprehensive “CARE” approach in the ESC guideline published in 2024. Drug therapy for atrial fibrillation is primarily aimed at preventing...…
View Post 5 min This content is machine translated Side effects under opioid therapy Is it possible to avoid the inevitable? Opioid analgesics are an essential tool for the relief of cancer-related pain. However, in addition to their undeniable therapeutic value, opioids are associated with a number of predictable side effects...…
View Post 9 min This content is machine translated Diagnostics of respiratory viral infections What is tested when and on whom? The diagnosis of respiratory viral infections has become a major focus of medical attention in recent years. While SARS-CoV-2 has taken center stage in recent years, other respiratory viruses such...… CME-Test
View Post 11 min This content is machine translated From statins to metformin Preventive pharmacology and longevity In medicine, “longevity” is now less anti-ageing marketing than a very specific question of precision prevention: which pharmacological interventions prevent (or delay) cardiometabolic, renal, oncological and functional endpoints – and...…
View Post 11 min This content is machine translated Alternative to insulin and GLP1 From the β-cell to the center: the versatile role of amylin Although amylin was discovered decades ago, its importance in everyday clinical practice has long been underestimated. New pharmacological developments are increasingly bringing amylin into the focus of diabetes and obesity...… CME-Test
View Post 6 min This content is machine translated Severe acute pancreatitis COX-2 inhibition alleviates inflammation and improves outcomes Severe acute pancreatitis represents a persistent therapeutic challenge due to its unpredictable course and the lack of targeted pharmacological options. Despite improved supportive care, mortality remains high, especially in cases...…
View Post 2 min This content is machine translated Ulcerative colitis Rgs14 protein can worsen the severity Rgs14 is a protein that acts as a regulator of G-protein signaling pathways by accelerating the GTPase activity of G-protein alpha subunits and thereby converting them to their inactive GDP-bound...…
View Post 8 min This content is machine translated Mastocytosis Innovative pathogenesis-based therapeutic approaches in the pipeline The treatment of mastocytosis has undergone a paradigm shift in recent years. A deeper molecular understanding of the disease has paved the way from a purely symptomatic to a targeted,...…
