This content is machine translated Disease-modifying therapies for ATTR-CM TTR stabilizers, gene silencing and gene scissors: where do we stand? Advances in the understanding of the pathophysiology of transthyretin amyloid cardiomyopathy (ATTR-CM) have revolutionized the therapeutic landscape in recent years. TTR stabilizers such as tafamidis and acoramidis can reduce TTR...…
View Post 8 min This content is machine translated Proteins in wound healing Do special amino acids lead to success? Wound healing is a complex process. Depending on which wound healing phase you are in, a wide variety of mediators are involved. A finely tuned combination of all basic nutrients...… CME-Test
View Post 4 min This content is machine translated HER2+ early breast cancer DESTINY-Breast11 – neoadjuvant T-DXd without anthracyclines The phase III DESTINY-Breast11 trial shows that neoadjuvant trastuzumab deruxtecan (T-DXd) could provide an anthracycline-free treatment option for HER2-positive early breast cancer. The results suggest an effective and better tolerated...…
View Post 3 min This content is machine translated Lavender aromatherapy Take away the fear of the dentist Fear of the dentist is still widespread and often leads to avoidance of treatment and a resulting deterioration in oral health. Supplementary non-pharmacological measures are increasingly being used to make...…
View Post 4 min This content is machine translated Digital dermatology: innovative project examples AI and eHealth tools in HS care A key concern in the field of digital dermatology is to effectively translate scientific findings into practical digital applications. The rapid development of artificial intelligence (AI) techniques, in particular deep...…
View Post 3 min This content is machine translated Dementia risk with type 2 diabetes SGLT2 inhibitors with advantages vs. DPP4 inhibitors SGLT2 inhibitors are associated with a significantly lower risk of dementia, including Alzheimer’s disease and vascular dementia, compared to DPP4 inhibitors. The observed benefit was consistent across different subgroups and...…
View Post 4 min This content is machine translated Cannabis for schizophrenia CBD pre-treatment could exacerbate side effects A significant proportion of people with schizophrenia use cannabis, with around one in five meeting the criteria for a comorbid cannabis use disorder, for which there are still limited effective...…
View Post 11 min This content is machine translated Type 2 diabetes: cardiovascular risk reduction is realistic Modern active ingredients and lifestyle – every step counts Although diabetics have an increased risk of developing cardiovascular diseases such as myocardial infarction, heart failure or stroke, scientific data suggests that protective effects can be achieved through the best...…
View Post 4 min This content is machine translated Lichen sclerosus Interim analysis of a new register So far, 60 patients1 with lichen sclerosus were included in the registry launched in Germany. The mean age of the included patients is 54 years 2. An interim assessment shows...…
View Post 8 min This content is machine translated Urothelial carcinoma Immune and targeted therapy options: Evidence situation 2025/2026 The treatment of urothelial carcinoma has developed significantly in recent years. Modern immunotherapies, antibody-drug conjugates (ADCs) and targeted substances complement conventional chemotherapies and increasingly enable individualized treatment strategies. New data...…
View Post 5 min This content is machine translated SGLT2 inhibitors for type 2 diabetes and CKD Prediction model beats albuminuria threshold SGLT2 inhibitors also significantly reduce the risk of kidney disease progression in patients with type 2 diabetes and preserved kidney function, whereby the relative benefit is independent of albuminuria status....…
