This content is machine translated Urothelial carcinoma Immune and targeted therapy options: Evidence situation 2025/2026 The treatment of urothelial carcinoma has developed significantly in recent years. Modern immunotherapies, antibody-drug conjugates (ADCs) and targeted substances complement conventional chemotherapies and increasingly enable individualized treatment strategies. New data...…
View Post 5 min This content is machine translated SGLT2 inhibitors for type 2 diabetes and CKD Prediction model beats albuminuria threshold SGLT2 inhibitors also significantly reduce the risk of kidney disease progression in patients with type 2 diabetes and preserved kidney function, whereby the relative benefit is independent of albuminuria status....…
View Post 4 min This content is machine translated Risk of psychosis Modulate cortical excitatory activity with diazepam Individuals at clinical high risk for psych osis (CHRp) have an estimated 27% chance of developing a psychotic disorder within three years, but there are currently no established preventive pharmacological...…
View Post 6 min This content is machine translated MASLD/MASH: lifestyle, pharmacotherapy, bariatric procedures Addressing metabolic drivers and counteracting fibrosis Steatotic liver diseases that are not associated with alcohol consumption are now referred to as metabolic steatotic liver disease (MASLD) or metabolic dysfunction-associated steatohepatitis (MASH). There is now no need...…
View Post 9 min This content is machine translated Experiences from the EFFORT studies Solutions to the malnutrition dilemma The term malnutrition encompasses more than just insufficient food intake; it is an independent clinical picture with clearly defined effects on complication rates, functionality and mortality, which can be influenced...… CME-Test
View Post 6 min This content is machine translated Chronic urticaria: new treatment alternatives in sight If antihistamines are not sufficient and IgE levels are low Chronic urticaria often leads to a high level of suffering, but new treatment options are on the way – a lot has happened since the publication of the current S3...…
View Post 12 min This content is machine translated Treatable risk factor Depression and cardiovascular mortality New meta-analyses, the first ESC consensus document on mental health and heart disease and groundbreaking Lancet dataon antidepressant drugs show: Depression is an independent, quantifiable and treatable risk factor for...…
View Post 6 min This content is machine translated Hypertrophic cardiomyopathies (HCM) How do myosin inhibitors perform in different HCM phenotypes? Cardiac myosin inhibitors have been developed as a targeted therapeutic option for modulating sarcomere function. While in clinical trials in obstructive hypertrophic cardiomyopathy they brought about a greater improvement in...…
View Post 12 min This content is machine translated What are the benefits of a current review - and where do questions remain unanswered? Endometriosis and infertility Endometriosis affects an estimated 2-10% of women of reproductive age – the prevalence among infertile women is 25-50%. And yet there is still no clear, standardized treatment pathway for patients...…
View Post 7 min This content is machine translated Chronic hand eczema Occupational health aspects and modern therapy management Hand eczema is caused by a complex interaction of genetics, environment and immunological dysregulation. Cumulative exposure to irritants is a major driver of occupational hand eczema. Accordingly, a medical history...…
View Post 15 min This content is machine translated Cardiovascular health in women Hormonal contraception, stress disorders and cardiovascular risk in women Cardiovascular disease is the leading cause of death in women, and stress-related psychiatric disorders are considered cardiovascular risk factors in their own right. Hormonal contraceptives, which are used by around...…
