This content is machine translated Wrinkle Treatment with Botulinum Toxin: Current Trends The “Hotspots” Theory and the Moose Injection Technique A recent review article summarized findings on motor microinnervation and the topography of neuromuscular end plates in the muscles of the upper half of the face to facilitate the best...…
View Post 8 min This content is machine translated Chronic Urticaria: Treatment for Patients Unresponsive to Antihistamines In addition to anti-IgE antibodies, the guideline recommends anti-IL-4α antibodies and BTK inhibition The 2026 revised edition of the international urticaria guidelines incorporates the latest findings on pathogenesis and treatment options. Chronic spontaneous urticaria (CSU) encompasses various immunological endotypes with implications for the...…
View Post 8 min This content is machine translated Chronic hand eczema: common, long-lasting, and distressing Non-steroidal anti-inflammatory treatment options are essential for long-term management Chronic hand eczema (CHE) is one of the most persistent inflammatory skin conditions in adults. About one-third of patients suffer from moderate to severe hand eczema. The treatment of CHE...…
View Post 5 min This content is machine translated New COPD Treatments Targeting the inflammation—but for whom and when? Up to 50% of people with COPD continue to experience exacerbations despite receiving maximum inhaled therapy. The key factor here is persistent chronic inflammation, which cannot be fully controlled even...…
View Post 5 min This content is machine translated Tourette Syndrome What can be done to treat this tic disorder? Gilles de la Tourette syndrome (or “Tourette syndrome” for short) is a neurodevelopmental disorder characterized by motor and vocal tics and often accompanied by attention deficits, hyperactivity, and obsessive-compulsive disorder....…
View Post 4 min This content is machine translated Chronic Hepatitis B: Is a Cure in Sight? Phase III Trial of Temporary Treatment with Bepirovirsen Was Successful Hepatitis B is the most common form of viral hepatitis worldwide—dreaded complications include liver cirrhosis and hepatocellular carcinoma (HCC). Treatment with Bepirovirsen, an antisense oligonucleotide that targets mRNAs of the...…
View Post 5 min This content is machine translated Clinically Suspected Arthralgias “Watchful waiting” or intervention? The pathogenesis of rheumatoid arthritis (RA) begins years before clinical manifestation, but not all patients with joint pain develop RA. Since the primary care physician or internist’s office is usually...…
View Post 6 min This content is machine translated Upper GI Tract Bleeding: Hematemesis, Hematochezia, or Melena? From Risk Stratification to Post-Endoscopic Management Managing patients with acute upper gastrointestinal bleeding can be a balancing act. Clinical scores are helpful for time-sensitive risk assessment in the emergency department: Is the patient stable? Is urgent...…
View Post 15 min This content is machine translated Obesity, Nutrition, and Mental Health Depression, Binge Eating, Internalized Stigma Cardiometabolic outcomes rightly dominate obesity care. However, the psychological dimension is by no means a footnote: depression, disordered eating, and an often-overlooked internalized weight stigma influence the burden of disease,...…
View Post 5 min This content is machine translated From Hypertension to Heart Failure? When and how to intervene High blood pressure and hypertensive heart disease are the most significant risk factors for heart failure. The symptoms are very nonspecific, especially in the early stages of heart failure. Measuring...…
View Post 10 min This content is machine translated Switzerland's First PTH Replacement Therapy Palopegteriparatide for Chronic Hypoparathyroidism Chronic hypoparathyroidism is one of the few endocrine disorders for which no causal hormone replacement therapy has been available for decades. Treatment focused not on the underlying hormone deficiency, but...…
