Pemphigus – from diagnosis to therapy

Pemphigus diseases are potentially life-threatening, blistering autoimmune diseases. Acantholysis is detected by skin or mucosal biopsy. In this case study, an 82-year-old man was referred for a dermatological examination due to a generalized exanthema affecting the oral mucosa. The skin and mucosal changes had started two months ago and were accompanied by blistering, pain and pruritus.