Medizinonline Medizinonline
  • News
    • News
    • Market & Medicine
  • Patients
    • Disease patterns
    • Diagnostics
    • Therapy
  • Partner Content
    • Dermatology
      • Atopic dermatitis and psoriasis news
      • Dermatology News
    • Diabetes
      • Dia-Month Club – Type 2 Diabetes
      • Diabetes in Motion
      • Diabetes Podcasts
    • Gastroenterology
      • IBD matters
      • Forum Gastroenterology
      • Ozanimod: ulcerative colitis
      • Reflux Update
    • Immunology
      • Primary immunodeficiency – exchange of experience
    • Vaccinate
      • Herpes zoster
    • Infektiologie
    • Neurology
      • EXPERT ULTRASONIC: Introduction to ultrasound-guided injection
      • MS News
      • MS Therapy in Transition
    • Oncology
      • Swiss Oncology in motion
    • Orthopedics
      • Osteoporosis in motion
    • Phytotherapie
    • Practice Management
      • Aargau Cantonal Bank
      • Claraspital
    • Psychiatry
      • Geriatric Psychiatry
    • Rheumatology
  • Departments
    • Allergology and clinical immunology
    • General Internal Medicine
    • Anesthesiology
    • Angiology
    • Surgery
    • Dermatology and venereology
    • Endocrinology and Diabetology
    • Nutrition
    • Gastroenterology and Hepatology
    • Genetics
    • Geriatrics
    • Gynecology
    • Hematology
    • Infectiology
    • Cardiology
    • Nephrology
    • Neurology
    • Emergency and intensive care medicine
    • Nuclear Medicine
    • Oncology
    • Ophthalmology
    • ORL
    • Orthopedics
    • Pediatrics
    • Pharmacology and toxicology
    • Pharmaceutical medicine
    • Phlebology
    • Physical medicine and rehabilitation
    • Pneumology
    • Prevention and health care
    • Psychiatry and psychotherapy
    • Radiology
    • Forensic Medicine
    • Rheumatology
    • Sports Medicine
    • Traumatology and trauma surgery
    • Tropical and travel medicine
    • Urology
    • Dentistry
  • CME & Congresses
    • CME continuing education
    • Congress Reports
    • Congress calendar
  • Practice
    • Noctimed
    • Practice Management
    • Jobs
    • Interviews
  • Log In
  • Register
  • My account
  • Contact
  • English
    • Deutsch
    • Français
    • Italiano
    • Português
    • Español
  • Publications
  • Contact
  • Deutsch
  • English
  • Français
  • Italiano
  • Português
  • Español
Subscribe
Medizinonline Medizinonline
Medizinonline Medizinonline
  • News
    • News
    • Market & Medicine
  • Patienten
    • Krankheitsbilder
    • Diagnostik
    • Therapie
  • Partner Content
    • Dermatology
      • Atopic dermatitis and psoriasis news
      • Dermatology News
    • Diabetes
      • Dia-Month Club – Type 2 Diabetes
      • Diabetes in Motion
      • Diabetes Podcasts
    • Gastroenterology
      • IBD matters
      • Forum Gastroenterology
      • Ozanimod: ulcerative colitis
      • Reflux Update
    • Immunology
      • Primary immunodeficiency – exchange of experience
    • Vaccinate
      • Herpes zoster
    • Infektiologie
    • Neurology
      • EXPERT ULTRASONIC: Introduction to ultrasound-guided injection
      • MS News
      • MS Therapy in Transition
    • Oncology
      • Swiss Oncology in motion
    • Orthopedics
      • Osteoporosis in motion
    • Phytotherapie
    • Practice Management
      • Aargau Cantonal Bank
      • Claraspital
    • Psychiatry
      • Geriatric Psychiatry
    • Rheumatology
  • Departments
    • Fachbereiche 1-13
      • Allergology and clinical immunology
      • General Internal Medicine
      • Anesthesiology
      • Angiology
      • Surgery
      • Dermatology and venereology
      • Endocrinology and Diabetology
      • Nutrition
      • Gastroenterology and Hepatology
      • Genetics
      • Geriatrics
      • Gynecology
      • Hematology
    • Fachbereiche 14-26
      • Infectiology
      • Cardiology
      • Nephrology
      • Neurology
      • Emergency and intensive care medicine
      • Nuclear Medicine
      • Oncology
      • Ophthalmology
      • ORL
      • Orthopedics
      • Pediatrics
      • Pharmacology and toxicology
      • Pharmaceutical medicine
    • Fachbereiche 26-38
      • Phlebology
      • Physical medicine and rehabilitation
      • Phytotherapy
      • Pneumology
      • Prevention and health care
      • Psychiatry and psychotherapy
      • Radiology
      • Forensic Medicine
      • Rheumatology
      • Sports Medicine
      • Traumatology and trauma surgery
      • Tropical and travel medicine
      • Urology
      • Dentistry
  • CME & Congresses
    • CME continuing education
    • Congress Reports
    • Congress calendar
  • Practice
    • Noctimed
    • Practice Management
    • Jobs
    • Interviews
Login

Sie haben noch keinen Account? Registrieren

  • Diabetic ketoacidosis

Study: ketoacidosis in infancy affects brain development

    • Endocrinology and Diabetology
    • Neurology
    • Partner Content
    • Pediatrics
    • RX
    • Studies
  • 3 minute read

Diabetic ketoacidosis (DKA) can have consequences for a child’s brain, an American research group shows in the journal Diabetes Care. The German Diabetes Society (DDG) points out the need to diagnose children with type 1 diabetes at an early stage and to monitor their metabolic status closely in order to avoid possible consequential damage due to severe ketoacidosis.

In a study published in the journal Diabetes Care, researchers found that severe diabetic ketoacidosis (DKA) can lead to cognitive impairment in children.1 “A moderate to severe metabolic derailment has a negative effect on attention performance in those affected – compared to the group of children who had no or only mild DKA,” said DDG Vice President Professor Andreas Neu, MD, summarizing the findings. “This finding is alarming. After all, more than one in five children are hospitalized with ketoacidosis when diabetes manifests, and in about six percent of cases, severe DKA is already present.”

To date, there has been little scientific evidence on the extent to which an episode of diabetic ketoacidosis in infancy affects brain development and thus cognitive performance in children with type 1 diabetes. The American research team led by Tandy Aye has now examined data from 144 children with type 1 diabetes between the ages of four and ten. Of these children, the researchers took a brain scan and cognitive tests at baseline and after 18 months and compared the results. This showed a correlation between the severity of ketoacidosis, brain growth, and cognitive performance.

More parent education needed – especially during Corona pandemic

“The study shows that, particularly in young children, a severe insulin deficiency and the resulting hyperacidity in the blood can have consequences for brain development and for the ability to learn and concentrate,” explains private lecturer Dr. med. Thomas Kapellen, chairman of the AG Pädiatrische Diabetologie der DDG from Leipzig. This makes it all the more important to focus even more on individual diabetes education for children and parents, he said: “To avoid DKA, parents need to be able to recognize the first symptoms. Here, too, we need more education.”

In addition to increased thirst, a strong urge to urinate, weight loss, nausea and vomiting, the first signs of DKA include accelerated breathing and an acetone odor in the breath. Since muscle weakness, impaired consciousness or a diabetic coma can occur in the further course, affected children belong immediately in emergency medical care. “Especially during the current corona period, classic symptoms such as accelerated breathing can be misinterpreted and mistaken for a respiratory infection,” Kapellen warns. “Valuable time can pass here until the actual cause is determined.”

For example, a recent JAMA publication from Germany showed that the rate of ketoacidosis in diabetes manifesting children and adolescents doubled during the corona lockdown.2 “During this time, almost every second child received a delayed diagnosis,” summarizes Professor Reinhard Holl, MD, co-author of the study and coordinator of the DPV registry. Young children were particularly affected. In addition to misinterpretation of the symptoms by parents or physicians, this can also be attributed to the fear of infection with COVID-19 in doctors’ offices and clinics. The DDG expert from Ulm warns that another wave could lead to a similar situation and calls on parents and everyone who works with children and adolescents to take the first warning signs seriously and, if necessary, to consult a pediatrician or a pediatric clinic immediately.

Source: German Diabetes Society

Previous Article
  • Chronic wounds

Evidence provided: cold plasma effective in chronic wounds

  • Endocrinology and Diabetology
  • RX
View Post
Next Article
  • GLP-1 receptor agonists in type 2 diabetes

Nephroprotection with semaglutide and liraglutide – direct or indirect effects?

  • Congress Reports
  • Endocrinology and Diabetology
  • General Internal Medicine
  • Nephrology
  • Partner Content
  • RX
  • Studies
View Post
You May Also Like
View Post
  • 6 min
  • Latent autoimmune diabetes in adults (LADA)

Looks like type 2, but is type 1

    • Cases
    • Education
    • Endocrinology and Diabetology
    • RX
    • Studies
View Post
  • 6 min
  • Treatment of vitiligo

Focus on patient perspective and disease activity

    • Congress Reports
    • Dermatology and venereology
    • Pharmacology and toxicology
    • RX
    • Studies
View Post
  • 5 min
  • Vaccine-preventable respiratory diseases

RSV and pneumococci: recommendations for risk groups

    • Congress Reports
    • General Internal Medicine
    • Infectiology
    • Pediatrics
    • Pneumology
    • Prevention and health care
    • RX
    • Studies
View Post
  • 5 min
  • Circadian rhythm in asthma

Chronotherapy can improve control

    • Allergology and clinical immunology
    • General Internal Medicine
    • Pneumology
    • RX
    • Studies
View Post
  • 6 min
  • Update on diagnostics, risk stratification and therapy

Acute myeloid leukemia 2025

    • Education
    • Hematology
    • Oncology
    • RX
    • Studies
View Post
  • 4 min
  • New practice guideline for fibromyalgia syndrome

Good times, bad times

    • Congress Reports
    • General Internal Medicine
    • Neurology
    • Pharmacology and toxicology
    • Physical medicine and rehabilitation
    • Rheumatology
    • RX
    • Sports Medicine
    • Studies
View Post
  • 5 min
  • Findings from the TRACK-FA study

Neuroimaging biomarkers in Friedreich’s ataxia

    • Genetics
    • Neurology
    • Pediatrics
    • RX
    • Studies
View Post
  • 12 min
  • Doing sport without fear or risk

Doing sport without fear or risk

    • CME continuing education
    • Endocrinology and Diabetology
    • Pediatrics
    • RX
    • Sports Medicine
Top Partner Content
  • Forum Gastroenterology

    Zum Thema
  • Herpes zoster

    Zum Thema
Top CME content
  • 1
    Doing sport without fear or risk
  • 2
    UV protection and skin cancer screening – Update 2025
  • 3
    Rare malignancy from a dermatological perspective
  • 4
    Yellow nail and Swyer-James syndrome
  • 5
    Diagnostic indications

Newsletter

Sign up and stay up to date

Subscribe
Medizinonline
  • Contact
  • General terms and conditions
  • Imprint

Input your search keywords and press Enter.