View Post 5 minute read This content is machine translated Adherence in severe or poorly controlled asthma Digital monitoring with potential for greater treatment adherence Education Pneumology RX Studies Despite proven pharmacological strategies for the treatment of asthma, lack of adherence to inhaled therapy remains a major problem, particularly in patients requiring a triple combination. Digital tools have shown promise as a means of improving adherence, and some data suggest that they can also positively influence clinical outcomes…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
View Post 4 minute read This content is machine translated Crohn's disease and depression Significant psychological stress for CD patients Education Gastroenterology and Hepatology General Internal Medicine Psychiatry and psychotherapy RX Studies Crohn’s disease (CD) is often associated with extraintestinal symptoms (EIM). However, the connection with mental disorders is also being increasingly emphasized. Spanish scientists analyzed the frequency and severity of depression in patients with CD, shedding light on the often underestimated psychological dimension of this disease…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
View Post 4 minute read This content is machine translated Epilepsy Cannabidiol for refractory epilepsy syndromes Education Neurology Pharmaceutical medicine Pharmacology and toxicology Phytotherapy RX Studies The pharmaceutical formulation of high-purity cannabidiol is approved for the treatment of seizures associated with Lennox-Gastaut syndrome, Dravet syndrome and tuberous sclerosis complex. Despite many years of clinical experience, there is still uncertainty among practitioners…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
View Post 3 minute read This content is machine translated Stomach cancer and Helicobacter pylori A question of income? Education Gastroenterology and Hepatology Infectiology Oncology Prevention and health care RX Studies Despite a declining incidence rate, the total number of cases and deaths from gastric cancer continues to rise worldwide. Infection with Helicobacter pylori is the main risk factor for the disease; however, the burden caused by this bacterium is unevenly distributed across geographical regions and is not yet fully defined…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
View Post 7 minute read This content is machine translated Prurigo nodularis and AD Effective itch relief through inhibition of the IL-31 signaling pathway Allergology and clinical immunology Congress Reports Dermatology and venereology RX Studies The vicious circle of itching and scratching is a central element in both prurigo nodularis (PN) and atopic dermatitis (AD). Interleukin (IL)-31, often referred to as the “itch cytokine”, has been identified as a key cytokine in this process. Nemolizumab, a specific antagonist of the IL-31 receptor, enables targeted blockade of this signaling pathway. Current study data confirm the therapeutic potential in PN and AD…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
View Post 4 minute read This content is machine translated Cutaneous Crohn's disease Effective alternative to TNF inhibitors Dermatology and venereology Education Gastroenterology and Hepatology General Internal Medicine RX Cutaneous Crohn’s disease (CCD) is a granulomatous skin disease that is not associated with the gastrointestinal tract. It rarely correlates with intestinal disease and often requires separate treatment. Although interleukin (IL)-12/23 and IL-23 inhibitors are FDA-approved for intestinal Crohn’s disease, there are limited data on CCD…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
View Post 12 minute read This content is machine translated Palliative care symptom and needs assessment. What screening tools are helpful? CME continuing education Emergency and intensive care medicine General Internal Medicine Geriatrics Oncology Prevention and health care Psychiatry and psychotherapy RX Studies In view of the new and mostly well-tolerated therapies, the palliative life and treatment time of oncological patients is increasingly extended. It is a major challenge to identify patients in need of palliative support in an accurate and needs-based manner, as recommended in guidelines. In the context of Germany and Switzerland, a distinction is made between general palliative care (APV) and specialized palliative care (SPV)…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here CME-Test
View Post 4 minute read This content is machine translated Benralizumab in a patient with asthma and EGPA When the biologic has a counterproductive effect Cases Education General Internal Medicine Ophthalmology Pneumology Rheumatology RX Eosinophilic vasculitis with polyangiitis (EGPA) is a rare inflammation of small blood vessels that is usually associated with asthma. Eye involvement occurs sporadically and central retinal artery occlusion (CRAO) is an extremely rare but serious complication. During treatment with benralizumab, an EGPA with bilateral CRAO occurred…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
View Post 3 minute read This content is machine translated Brain atrophy and MS Brain atrophy correlates with disability progression in MS Education Neurology RX Studies Brain atrophy in MS patients, particularly in the thalamus, correlates strongly with long-term physical disability and cognitive deficits. A long-term analysis of the phase 3 studies RADIANCE/SUNBEAM and the open-label extension DAYBREAK now examines the efficacy of ozanimod over seven years. The results confirm sustained protection against volume loss and highlight the predictive role of brain volume biomarkers…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
View Post 15 minute read This content is machine translated Diabetes mellitus Treatment of comorbidities in older people Cardiology CME continuing education Endocrinology and Diabetology General Internal Medicine Geriatrics RX One in five people over 65 and one in four people over 75 are affected by diabetes. Global projections predict a 2.5-fold increase in diabetes prevalence over the next 25 years. Among older people with diabetes, 30–45% are affected by frailty. The risk of frailty increases with increasing HbA1c. The incidence of atherosclerotic cardiovascular disease (ASCVD) doubles with age, with a prevalence of 38.5% for coronary heart disease (CHD), 13% for stroke and 12% for peripheral arterial disease (PAD) in people aged ≥70 years. In addition to their glucose-controlling effect, new antidiabetic drugs have organ-protective benefits and have brought about a paradigm shift in diabetology…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt… CME-Test
Patient-centered rounds in medicine Aligning care with the patient CME continuing education Education General Internal Medicine Prevention and health care RX Studies View Post
Findings from the ALS Symposium 2024 in Montreal Current and future approaches in the treatment of amyotrophic lateral sclerosis (ALS) CME continuing education Congress Reports Interviews Neurology RX Studies View Post
Findings from the ALS Symposium 2024 in Montreal Current and future approaches in the treatment of amyotrophic lateral sclerosis (ALS) Congress Reports Interviews Neurology RX Studies View Post
Artificial intelligence in medicine Opportunities and risks of AI RX CME continuing education Dermatology and venereology Education General Internal Medicine Prevention and health care View Post
Artificial intelligence in medicine Opportunities and risks of AI RX CME continuing education Dermatology and venereology Education General Internal Medicine Prevention and health care View Post
Patient-centered rounds in medicine Aligning care with the patient RX CME continuing education Education General Internal Medicine Prevention and health care Studies View Post
Thyroid Diseases Clarification of thyroid nodules RX CME continuing education Education Endocrinology and Diabetology General Internal Medicine Nuclear Medicine Oncology Radiology View Post
Patient-centered rounds in medicine Aligning care with the patient RX CME continuing education Education General Internal Medicine Prevention and health care Studies View Post
Patient-centered rounds in medicine Aligning care with the patient RX CME continuing education Education General Internal Medicine Prevention and health care Studies View Post
Advanced urothelial carcinoma of the urinary bladder Systemic therapy RX CME continuing education Education Oncology Studies Urology View Post
View Post This content is machine translated Palliative care symptom and needs assessment. What screening tools are helpful? CME continuing education Emergency and intensive care medicine General Internal Medicine Geriatrics Oncology Prevention and health care Psychiatry and psychotherapy RX Studies In view of the new and mostly well-tolerated therapies, the palliative life and treatment time of oncological patients is increasingly extended. It is a major challenge to identify patients in need of palliative support in an accurate and needs-based manner, as recommended in guidelines. In the context of Germany and Switzerland, a distinction is made between general palliative care (APV) and specialized palliative care (SPV)…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here CME-Test
View Post This content is machine translated Diabetes mellitus Treatment of comorbidities in older people Cardiology CME continuing education Endocrinology and Diabetology General Internal Medicine Geriatrics RX One in five people over 65 and one in four people over 75 are affected by diabetes. Global projections predict a 2.5-fold increase in diabetes prevalence over the next 25 years. Among older people with diabetes, 30–45% are affected by frailty. The risk of frailty increases with increasing HbA1c. The incidence of atherosclerotic cardiovascular disease (ASCVD) doubles with age, with a prevalence of 38.5% for coronary heart disease (CHD), 13% for stroke and 12% for peripheral arterial disease (PAD) in people aged ≥70 years. In addition to their glucose-controlling effect, new antidiabetic drugs have organ-protective benefits and have brought about a paradigm shift in diabetology…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt… CME-Test
View Post This content is machine translated Alternative to insulin and GLP1 From the β-cell to the center: the versatile role of amylin CME continuing education Endocrinology and Diabetology RX Studies Although amylin was discovered decades ago, its importance in everyday clinical practice has long been underestimated. New pharmacological developments are increasingly bringing amylin into the focus of diabetes and obesity therapy, and amylin analogs, some of which have already passed phase 3 clinical trials, are now among the most promising approaches in overweight and obesity pharmacotherapy…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here CME-Test
View Post This content is machine translated Artificial intelligence Dr. ChatGPT: Large language models in everyday clinical practice Cases CME continuing education General Internal Medicine Prevention and health care RX With the public availability of ChatGPT 3.5 in fall 2022 at the latest, artificial intelligence in the sense of large language models (LLMs) is on everyone’s lips. However, it is often forgotten that this is only the provisional end point of decades of development of artificial intelligence, which, despite its great potential, still has many limitations. The question for practising doctors is how this technology can be used sensibly in everyday clinical practice – and how it should not be used…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here CME-Test
