View Post 13 minute read This content is machine translated Why lipoprotein(a) is the biggest therapeutic vacuum in cardiology Lp(a): The underestimated risk factor before the turning point Cardiology Education Endocrinology and Diabetology RX Studies One in five people worldwide has a genetically elevated lipoprotein(a) – and knows nothing about it. Unlike LDL cholesterol, this independent, causally significant risk factor cannot be significantly influenced by diet, exercise or statins. This therapeutic gap has existed for decades. Now we are close to the turning point: RNA-based drugs reduce Lp(a) by up to 95%, and the first cardiac outcomes study, Lp(a)HORIZON, expects its results in the first half of 2026. The Focused Update of the ESC/EAS dyslipidemia guidelines published in 2025 anchors Lp(a) as a mandatory screening target for all adults for the first time…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
View Post 11 minute read This content is machine translated Modern system therapeutics for hidradenitis suppurativa Immunological dysregulation in the sights of several biologics and “small molecules” Allergology and clinical immunology Dermatology and venereology Education RX Studies The approval of anti-TNF and anti-IL-17 antibody therapies for moderate to severe courses of hidradenitis suppurativa has significantly improved the drug treatment options for this debilitating and potentially mutilating disease of the terminal hair gland apparatus in recent years. In addition, there is a promising arsenal of immunomodulatory drugs in the pipeline, including interleukin antibodies and JAK-i, as well as nanobodies, BTK and SYK inhibitors…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
View Post 15 minute read This content is machine translated Perimenopausal depression, PMDS and tokophobia Psychosomatics and mental health in gynecology Education Gynecology Psychiatry and psychotherapy RX Studies Mental illnesses in women are common, serious – and systematically underdiagnosed in gynecological practice. The tripled risk of depression in the perimenopause, PMDS (premenstrual dysphoric disorder), which is recognized as an independent psychiatric diagnosis, and pathological fear of childbirth (tokophobia) directly affect daily care in gynaecological practices. Each of these entities has a clear biological basis, classifiable symptoms, validated diagnostic tools and evidence-based treatment options – and yet it often takes years between the first symptom and the correct diagnosis…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
View Post 8 minute read This content is machine translated Proteins in wound healing Do special amino acids lead to success? CME continuing education Dermatology and venereology Endocrinology and Diabetology Nutrition RX Studies Wound healing is a complex process. Depending on which wound healing phase you are in, a wide variety of mediators are involved. A finely tuned combination of all basic nutrients (carbohydrates, proteins, fats), minerals, vitamins and trace elements is required as a basis for this. This shows the relevance of an adequate nutrient supply for wound healing…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here CME-Test
View Post 7 minute read This content is machine translated Plastic surgery and reconstructive microsurgery for DFS Functional limb preservation between infection control, vascular medicine and resurfacing Angiology CME continuing education Endocrinology and Diabetology General Internal Medicine Geriatrics Physical medicine and rehabilitation RX Surgery Diabetic foot syndrome (DFS) is one of the most serious and functionally significant complications of diabetes, with a high number of functionally relevant amputations. DFS is not to be understood as an isolated chronic wound, but as a local manifestation of a systemic metabolic disease with neurovascular and immunological dysregulation and destruction…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here CME-Test
View Post 9 minute read This content is machine translated Polycystic ovary syndrome 2025/2026 New pathophysiology, updated diagnostics and the age of incretin mimetics Education Gastroenterology and Hepatology General Internal Medicine Gynecology Pharmacology and toxicology RX Studies With a prevalence of 8-13%, polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age – and yet up to 70% of those affected remain undiagnosed. In 2025 and 2026, new insights into the pathophysiology have fundamentally expanded the picture of PCOS: the gut-microbiome axis, the neuroendocrine gut-brain axis and chronic low-grade inflammation are playing an increasingly central role. At the same time, GLP-1 receptor agonists such as semaglutide and tirzepatide are experiencing a clinical breakthrough as an off-label option for PCOS with a metabolic phenotype…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
View Post 14 minute read This content is machine translated Heart failure and type 2 diabetes Oral semaglutide and cardiac decompensation in type 2 diabetes Cardiology Education Endocrinology and Diabetology RX Studies The secondary analysis of the SOUL trial from JAMA Internal Medicine 2026 proves for the first time: Oral semaglutide significantly reduces heart failure events in patients with pre-existing HFpEF – without safety signals, even with concomitant SGLT2 inhibitor therapy. Heart failure is one of the most common and prognostically most serious complications of type 2 diabetes. GLP-1 receptor agonists in subcutaneous formulation have already been shown to be effective in reducing heart failure events. With the secondary analysis of the SOUL trial, comprehensive data is now available for the first time for the oral formulation of semaglutide – and it shows: Heart failure outcomes are improved primarily in patients with preserved ejection fraction (HFpEF), while no effect is…
View Post 7 minute read This content is machine translated Atopic dermatitis as a door opener for an atopic cascade? AD trajectories: Summary of current findings Allergology and clinical immunology Congress Reports Dermatology and venereology RX Studies Epidemiologic analyses and longitudinal studies show that the majority of infants affected by AD are symptom-free as adults, but in some, AD persists into adulthood. This is associated with an increased risk of developing IgE-mediated atopic comorbidities. Corresponding correlations have been deciphered in cohort studies. The knowledge gained from this can be helpful in counseling AD sufferers and their families…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
View Post 11 minute read This content is machine translated New evidence on descensus, urinary incontinence and the future of reconstruction Urogynecology and pelvic floor surgery 2026 Education General Internal Medicine Gynecology Physical medicine and rehabilitation RX Studies Surgery Urology Urogynecology and reconstructive pelvic floor surgery are in a phase of upheaval: the ban on transvaginal polypropylene mesh kits in many countries has fundamentally changed the surgical strategy and provided new impetus for native tissue repair techniques and minimally invasive approaches. At the same time, the AUA/SUFU Guideline 2024 has restructured the management of overactive bladder – moving away from rigid staged regimens towards patient-centered treatment choices. Robotic sacrocolpopexy is establishing itself as the standard for apical defects, and new findings on de novo stress incontinence after prolapse repair are influencing preoperative counseling…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a…
View Post 8 minute read This content is machine translated Proteins in wound healing Do special amino acids lead to success? CME continuing education Dermatology and venereology Endocrinology and Diabetology Nutrition RX Studies Wound healing is a complex process. Depending on which wound healing phase you are in, a wide variety of mediators are involved. A finely tuned combination of all basic nutrients (carbohydrates, proteins, fats), minerals, vitamins and trace elements is required as a basis for this. This shows the relevance of an adequate nutrient supply for wound healing…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here CME-Test
Patient-centered rounds in medicine Aligning care with the patient CME continuing education Education General Internal Medicine Prevention and health care RX Studies View Post
Patient-centered rounds in medicine Aligning care with the patient CME continuing education Education General Internal Medicine Prevention and health care RX Studies View Post
Findings from the ALS Symposium 2024 in Montreal Current and future approaches in the treatment of amyotrophic lateral sclerosis (ALS) CME continuing education Congress Reports Interviews Neurology RX Studies View Post
Findings from the ALS Symposium 2024 in Montreal Current and future approaches in the treatment of amyotrophic lateral sclerosis (ALS) Congress Reports Interviews Neurology RX Studies View Post
Artificial intelligence in medicine Opportunities and risks of AI RX CME continuing education Dermatology and venereology Education General Internal Medicine Prevention and health care View Post
Artificial intelligence in medicine Opportunities and risks of AI RX CME continuing education Dermatology and venereology Education General Internal Medicine Prevention and health care View Post
Patient-centered rounds in medicine Aligning care with the patient RX CME continuing education Education General Internal Medicine Prevention and health care Studies View Post
Thyroid Diseases Clarification of thyroid nodules RX CME continuing education Education Endocrinology and Diabetology General Internal Medicine Nuclear Medicine Oncology Radiology View Post
Patient-centered rounds in medicine Aligning care with the patient RX CME continuing education Education General Internal Medicine Prevention and health care Studies View Post
Patient-centered rounds in medicine Aligning care with the patient RX CME continuing education Education General Internal Medicine Prevention and health care Studies View Post
View Post This content is machine translated Proteins in wound healing Do special amino acids lead to success? CME continuing education Dermatology and venereology Endocrinology and Diabetology Nutrition RX Studies Wound healing is a complex process. Depending on which wound healing phase you are in, a wide variety of mediators are involved. A finely tuned combination of all basic nutrients (carbohydrates, proteins, fats), minerals, vitamins and trace elements is required as a basis for this. This shows the relevance of an adequate nutrient supply for wound healing…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here CME-Test
View Post This content is machine translated Plastic surgery and reconstructive microsurgery for DFS Functional limb preservation between infection control, vascular medicine and resurfacing Angiology CME continuing education Endocrinology and Diabetology General Internal Medicine Geriatrics Physical medicine and rehabilitation RX Surgery Diabetic foot syndrome (DFS) is one of the most serious and functionally significant complications of diabetes, with a high number of functionally relevant amputations. DFS is not to be understood as an isolated chronic wound, but as a local manifestation of a systemic metabolic disease with neurovascular and immunological dysregulation and destruction…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here CME-Test
View Post This content is machine translated Proteins in wound healing Do special amino acids lead to success? CME continuing education Dermatology and venereology Endocrinology and Diabetology Nutrition RX Studies Wound healing is a complex process. Depending on which wound healing phase you are in, a wide variety of mediators are involved. A finely tuned combination of all basic nutrients (carbohydrates, proteins, fats), minerals, vitamins and trace elements is required as a basis for this. This shows the relevance of an adequate nutrient supply for wound healing…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here CME-Test
View Post This content is machine translated Wound treatment Surgical wound complications CME continuing education Dermatology and venereology Endocrinology and Diabetology Geriatrics Physical medicine and rehabilitation RX Surgery Demographic change is also influencing the prevalence and therefore the relevance of postoperative complications. Surgical wound complications in particular not only have a negative impact on individual morbidity, mortality and quality of life, but also result in higher care requirements and rising healthcare costs. The focus is on risk factors, prevention, diagnosis and treatment of surgical wound complications…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here CME-Test