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  • 4 minute read
  • This content is machine translated From symptom to diagnosis

Abdominal Pain – Von Meyenburg Complexes of the Liver

Von Meyenburg complexes are believed to be a congenital malformation arising from embryonic remnants of the bile ducts. Based on current knowledge, these benign, tumor-like biliary hamartomas do not lead to complications. They are often incidental findings during autopsies, biopsies, or imaging studies, which may be relevant for differential diagnosis…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
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  • This content is machine translated Multiple sclerosis

Physical and psychosocial fatigue have the greatest impact on HRQoL

Fatigue is one of the most common and debilitating symptoms of multiple sclerosis (MS); it affects up to 75% of MS patients and contributes to a poorer quality of life, limited social participation, and impaired occupational functioning. In relapsing-remitting multiple sclerosis (RRMS), fatigue is a major factor in patients’ burden and reduced health-related quality of life (HRQoL)…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
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  • 9 minute read
  • This content is machine translated Congenital Vascular Malformations

Personalized Treatment Before a Planned Pregnancy

Vascular malformations have a prevalence of 1% and an incidence of 3–5 per 10,000. Anomalies can affect any organ system in children and adults. Mosaic mutations occurring during embryonic development lead to a segmental defect in the development of the vascular system, affecting the veins, arteries, lymphatic vessels, or a combination of all three…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
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  • 8 minute read
  • This content is machine translated Hyperhidrosis: Keep a Cool Head

An Overview of Important Treatment Options

Excessive sweating can significantly impair quality of life. Gravimetry and the iodine-starch test are important diagnostic methods. Various options are available for the conservative treatment of primary hyperhidrosis. Topical preparations containing aluminum chloride hexahydrate are the most commonly used. In addition, glycopyrronium bromide cream is now available as a topical anticholinergic. Other interventions include botulinum toxin injections, systemic anticholinergics, iontophoresis, and thermal procedures…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
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  • 6 minute read
  • This content is machine translated Sjögren's Syndrome in Early Childhood

Children often develop lymphomas

To date, there has been limited knowledge regarding the clinical features of pediatric Sjögren’s syndrome and its impact on quality of life. Because it is rare, it is often diagnosed late, and there is a lack of validated pediatric endpoints. British researchers have now investigated clinical phenotypes, disease activity, symptom burden, and treatment experience…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
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  • 4 minute read
  • This content is machine translated 2026 Vaccination Schedule: Important Changes

Updated Recommendations on Pneumococcal Disease and RSV

Competent medical counseling can help promote acceptance of vaccinations. To this end, it is crucial to always have the most up-to-date information. The current immunization schedule includes several relevant changes compared to the previous version—not only, but also in connection with the re-approval of vaccines. Regardless of this, there are some general principles that remain valid but deserve to be emphasized once again given their importance. These include, for example, the fact that systematic monitoring of vaccination status minimizes potentially dangerous gaps in vaccination coverage…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
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  • 12 minute read
  • This content is machine translated Multidrug-Resistant Pathogens in Wound Care

An Enemy in the Microbiome?

Patients whose wounds are colonized by multidrug-resistant pathogens (MDR) pose a particular challenge for infection prevention. In hospitals and long-term care facilities, appropriate hygiene measures must be taken to prevent further spread. On the other hand, however, it is also important not to place too much psychological strain on patients through strict isolation. In today’s clinical practice, wound care is performed while wearing protective clothing, but otherwise does not differ significantly from the care of wounds not colonized by MREs…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
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  • 14 minute read
  • This content is machine translated Rare Genodermatoses: From Diagnosis to Treatment

Darier’s Disease, also known as Follicular Keratosis – Update 2026

Darier’s disease is caused by pathogenic variants in the ATP2A2 gene. Advances in our understanding of its pathophysiology have paved the way for the development of innovative therapeutic approaches, but further research is needed to optimize patient outcomes. This is also reflected in the establishment of the International Task Force for Darier’s Disease (DD-ITF) in 2025. For patients with severe or refractory disease, oral retinoids are still considered the first-line systemic therapy, but there are an increasing number of case reports documenting the successful use of anti-inflammatory immunomodulatory therapies (JAK inhibitors, biologics). This suggests that complex inflammatory processes are involved in the pathogenesis…. Dieser Inhalt ist nur für Benutzer der Gruppe:…
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  • 6 minute read
  • This content is machine translated COPD: Biomarker-Guided Therapy Escalation

Biologics as the “new kids on the block”

What led to a paradigm shift in severe asthma several years ago is now also making its way into COPD treatment: targeted, phenotype-specific antibody therapy. Patients with severe COPD who continue to suffer from recurrent exacerbations despite triple therapy (LABA+LAMA+ICS) are primarily eligible for biologic therapy. With dupilumab and mepolizumab, two highly effective monoclonal antibodies have now received Swissmedic approval for the indication of COPD…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
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  • This content is machine translated Congenital Vascular Malformations

Personalized Treatment Before a Planned Pregnancy

Vascular malformations have a prevalence of 1% and an incidence of 3–5 per 10,000. Anomalies can affect any organ system in children and adults. Mosaic mutations occurring during embryonic development lead to a segmental defect in the development of the vascular system, affecting the veins, arteries, lymphatic vessels, or a combination of all three…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
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  • This content is machine translated Multidrug-Resistant Pathogens in Wound Care

An Enemy in the Microbiome?

Patients whose wounds are colonized by multidrug-resistant pathogens (MDR) pose a particular challenge for infection prevention. In hospitals and long-term care facilities, appropriate hygiene measures must be taken to prevent further spread. On the other hand, however, it is also important not to place too much psychological strain on patients through strict isolation. In today’s clinical practice, wound care is performed while wearing protective clothing, but otherwise does not differ significantly from the care of wounds not colonized by MREs…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
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  • This content is machine translated Rare Genodermatoses: From Diagnosis to Treatment

Darier’s Disease, also known as Follicular Keratosis – Update 2026

Darier’s disease is caused by pathogenic variants in the ATP2A2 gene. Advances in our understanding of its pathophysiology have paved the way for the development of innovative therapeutic approaches, but further research is needed to optimize patient outcomes. This is also reflected in the establishment of the International Task Force for Darier’s Disease (DD-ITF) in 2025. For patients with severe or refractory disease, oral retinoids are still considered the first-line systemic therapy, but there are an increasing number of case reports documenting the successful use of anti-inflammatory immunomodulatory therapies (JAK inhibitors, biologics). This suggests that complex inflammatory processes are involved in the pathogenesis…. Dieser Inhalt ist nur für Benutzer der Gruppe:…
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  • This content is machine translated Psychedelic-assisted therapy

Current status of PAT

Psychedelic substances such as LSD, psilocybin and MDMA have increasingly become the focus of science and clinical practice in recent years. The substances are used as part of so-called psychedelic-assisted therapies (PAT), in which psychotherapeutic treatment is combined with the temporary administration of these substances. After research and clinical use largely came to a standstill in the 1970s, modern, controlled studies are now available that provide promising but not yet conclusive data on efficacy and safety…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
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