View Post 5 minute read This content is machine translated Prurigo and PN Anti-inflammatory antipruritic therapy improves quality of life Allergology and clinical immunology Congress Reports Dermatology and venereology RX Studies Which mediators are causally involved in peripheral and central itch sensitization in the context of prurigo and prurigo nodularis (PN) and contribute to the maintenance of pruritus is currently being analysed in numerous research projects. With dupilumab and nemolizumab, two therapeutic approaches are now available that combine anti-inflammatory and antipruritic effects and have overcome the approval hurdles for the indication PN. Interesting data from pooled analyses and from the long-term extension phase of the respective approval-relevant studies are now available…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
View Post 7 minute read This content is machine translated Pathophysiology, clinical significance and therapeutic consequences Eosinophils in asthma Allergology and clinical immunology Education Pneumology RX Studies For a long time, eosinophils were regarded as the central effector cells of asthma and were interpreted in the classical model as a direct damaging agent of the epithelium, as an amplifier of bronchial hyperresponsiveness and as the main driver of type 2-mediated airway inflammation. Scientific developments over the past two decades have differentiated, expanded and in some cases questioned this picture. Are eosinophils in fact primary culprits – or merely markers of more complex immunological patterns? A new Lancet publication sheds some light on this…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
View Post 12 minute read This content is machine translated Urothelial carcinoma Perioperative innovations and organ-preserving strategies Education Nephrology Oncology RX Studies Urology Urothelial carcinoma is an aggressive tumor entity with high morbidity. In recent years, the perioperative treatment spectrum – particularly for muscle-invasive bladder cancer – has expanded significantly: Immune checkpoint inhibitors and antibody-drug conjugates complement classic platinum-based concepts, while parallel bladder- and organ-preserving protocols, biomarker approaches and structured perioperative care programs (geriatric co-management, ERAS) are gaining in importance. In urothelial carcinoma of the upper urinary tract, the risks of loss of kidney function, the question of the optimal timing of systemic therapy and nephron-sparing procedures are taking center stage – flanked by increasing knowledge of molecular characteristics (including FGFR3/HRAS)…
View Post 14 minute read This content is machine translated Artificial intelligence Dr. ChatGPT: Large language models in everyday clinical practice Cases CME continuing education General Internal Medicine Prevention and health care RX With the public availability of ChatGPT 3.5 in fall 2022 at the latest, artificial intelligence in the sense of large language models (LLMs) is on everyone’s lips. However, it is often forgotten that this is only the provisional end point of decades of development of artificial intelligence, which, despite its great potential, still has many limitations. The question for practising doctors is how this technology can be used sensibly in everyday clinical practice – and how it should not be used…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here CME-Test
View Post 3 minute read This content is machine translated GLA:D® program for back pain patients Fewer consultations and reduction in the use of painkillers Congress Reports General Internal Medicine Rheumatology RX Studies In a quasi-experimental Danish study of patients with lower back pain, participation in a structured self-management program led to a sustained reduction in the number of visits to the doctor and the use of painkillers over the observation period of three years…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
View Post 5 minute read This content is machine translated Nutrition for type 2 diabetes Not such a great tuber Congress Reports Endocrinology and Diabetology Nutrition RX Studies The link between potato consumption and the risk of type 2 diabetes has long been debated. Although potatoes are a staple food worldwide, rich in starch and with a high glycemic index, their role in metabolic health remains unclear. A recent study combining data from three large US cohorts and an updated meta-analysis of prospective studies provide new insights…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
View Post 4 minute read This content is machine translated From symptom to diagnosis Abdominal pain – external hernias Cases Education Gastroenterology and Hepatology General Internal Medicine Radiology RX Surgery If the hernia can be seen from the outside or if the protrusion resulting from a hernia leads from the inside of the body towards the skin, it is referred to as an external hernia. The most common external hernias are inguinal, umbilical, incisional, abdominal wall and femoral hernias. Different types of hernias can be reliably detected and classified using ultrasound, CT or MRI…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
View Post 10 minute read This content is machine translated Mechanisms, evidence and therapeutic consequences GLP-1 receptor agonists in cardiology Cardiology Education Endocrinology and Diabetology RX Studies GLP-1 receptor agonists (GLP-1RAs) have rapidly evolved from antidiabetic drugs to cardiometabolic therapies with clinically proven reductions in hard cardiovascular endpoints – and increasingly beyond the traditional diabetes population. The mechanistic basis ranges from anti-atherogenic and endothelium-protective effects to anti-inflammatory and direct cardiac protective mechanisms to substantial weight reduction with favorable changes in blood pressure and lipids. The following article introduces the physiological basis, critically classifies the outcome evidence and discusses liraglutide, semaglutide (s.c. and oral), dulaglutide, albiglutide, efpeglenatide, exenatide and lixisenatide in a substance-specific manner. Dual and triple incretin concepts are outlined in…
View Post 6 minute read This content is machine translated MASLD/MASH Drug therapy options on the rise: spectacular evidence Congress Reports Gastroenterology and Hepatology General Internal Medicine RX Studies Over the last few decades, the incidence of steatotic liver disease has risen in parallel with the increase in obesity, diabetes and other metabolic diseases. It is recommended to screen patients at risk in a targeted manner. Significant progress has been made in the recent past. Recent studies have identified subtypes of MASLD with different cardiovascular risk profiles. In the field of drug therapy for MASH, an important breakthrough has been achieved with the FDA and EMA approval of resmetirome. However, the data situation for subcutaneously administered semaglutide is also promising, as current interim analyses show…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
View Post 6 minute read This content is machine translated New ways of neuroregeneration CRISPR and artificial intelligence Education Genetics Neurology RX Studies The combination of precise genome editing using CRISPR and AI-supported modeling of complex CNS damage marks a paradigm shift in neuroregeneration. Adaptive, closed therapy loops are designed to address multiple molecular and cellular barriers simultaneously…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
Patient-centered rounds in medicine Aligning care with the patient CME continuing education Education General Internal Medicine Prevention and health care RX Studies View Post
Findings from the ALS Symposium 2024 in Montreal Current and future approaches in the treatment of amyotrophic lateral sclerosis (ALS) CME continuing education Congress Reports Interviews Neurology RX Studies View Post
Findings from the ALS Symposium 2024 in Montreal Current and future approaches in the treatment of amyotrophic lateral sclerosis (ALS) Congress Reports Interviews Neurology RX Studies View Post
Artificial intelligence in medicine Opportunities and risks of AI RX CME continuing education Dermatology and venereology Education General Internal Medicine Prevention and health care View Post
Artificial intelligence in medicine Opportunities and risks of AI RX CME continuing education Dermatology and venereology Education General Internal Medicine Prevention and health care View Post
Patient-centered rounds in medicine Aligning care with the patient RX CME continuing education Education General Internal Medicine Prevention and health care Studies View Post
Thyroid Diseases Clarification of thyroid nodules RX CME continuing education Education Endocrinology and Diabetology General Internal Medicine Nuclear Medicine Oncology Radiology View Post
Patient-centered rounds in medicine Aligning care with the patient RX CME continuing education Education General Internal Medicine Prevention and health care Studies View Post
Patient-centered rounds in medicine Aligning care with the patient RX CME continuing education Education General Internal Medicine Prevention and health care Studies View Post
Advanced urothelial carcinoma of the urinary bladder Systemic therapy RX CME continuing education Education Oncology Studies Urology View Post
View Post This content is machine translated Artificial intelligence Dr. ChatGPT: Large language models in everyday clinical practice Cases CME continuing education General Internal Medicine Prevention and health care RX With the public availability of ChatGPT 3.5 in fall 2022 at the latest, artificial intelligence in the sense of large language models (LLMs) is on everyone’s lips. However, it is often forgotten that this is only the provisional end point of decades of development of artificial intelligence, which, despite its great potential, still has many limitations. The question for practising doctors is how this technology can be used sensibly in everyday clinical practice – and how it should not be used…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here CME-Test
View Post This content is machine translated Music as a cure for cancer? Music therapy in Swiss oncology CME continuing education Congress Reports General Internal Medicine Oncology Prevention and health care Psychiatry and psychotherapy RX Studies Music therapy is becoming increasingly important as part of integrative treatment approaches and complementary procedures in cancer treatment. The workshop held by a music therapist from Inselspital Bern at this year’s SOHC in Basel used examples from clinical practice and self-awareness exercises to demonstrate the effectiveness of music therapy, which can be used both in palliative care and to accompany or support the healing process in cancer, as confirmed by scientific studies such as a study published in July 2025 Frontiers in Immunology …. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here CME-Test
View Post This content is machine translated COPD therapy Drug therapy – Update 2025 CME continuing education General Internal Medicine Pneumology RX Studies Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory multisystem disease caused primarily by inhaled noxious substances in combination with environmental factors and genetic predispositions. The presence of such a disease means that the comorbidities associated with COPD should be taken into account in both diagnosis and treatment. First and foremost, cardiovascular comorbidities should be mentioned. In the advanced stage, osteoporosis and muscle hypotrophy are important comorbidities that should be addressed…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here CME-Test
View Post This content is machine translated Diagnostics of respiratory viral infections What is tested when and on whom? CME continuing education General Internal Medicine Infectiology ORL Pneumology RX Studies The diagnosis of respiratory viral infections has become a major focus of medical attention in recent years. While SARS-CoV-2 has taken center stage in recent years, other respiratory viruses such as influenza and respiratory syncytial virus (RSV) are now increasingly coming to the attention of experts. In everyday clinical practice, the main challenge for medical staff is to select the right diagnostic methods for the respective clinical situation in order to enable a precise and prompt diagnosis and to initiate measures based on this…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here CME-Test
