View Post 8 minute read This content is machine translated A syndrome between decompensation and chronification Worsening Heart Failure Cardiology Education RX Studies The deterioration of chronic heart failure – so-called worsening heart failure (WHF) – is no longer solely an acute event, but an expression of complex, often repetitive pathophysiological dynamics. Despite improved pharmacotherapy, earlier diagnosis and more sophisticated monitoring, the hospitalization rate remains high and mortality within the first year after discharge is a cause for concern. New data show that WHF is not only the final stage of advanced heart failure, but is often triggered by treatable mechanisms: Volume shifts, inadequate neurohormone blockade, inflammatory or metabolic triggers and inadequate adherence to therapy…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
View Post 6 minute read This content is machine translated Actinic keratosis Field-directed therapy methods: what the European guideline recommends Allergology and clinical immunology Dermatology and venereology Education Oncology RX Studies Topically applied medications are a cornerstone of the field-directed treatment of actinic keratoses. In photodynamic therapy, a topical agent is combined with a procedural method. In cases of insufficient response, severe hyperkeratosis or in high-risk patients, other combined therapy strategies can also be considered, such as lesion-directed destruction of individual lesions followed by field-directed therapy. Immunocompromised patients have an increased risk of progression from AK lesions to cutaneous squamous cell carcinoma…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
View Post 4 minute read Education Geriatrics Neurology Pharmacology and toxicology RX Studies Opicapon: double benefit for motor function and sleep in Parkinson’s disease Sleep disorders are among the most common non-motor Parkinson’s symptoms. The targeted treatment of sleep disorders is an important part of Parkinson’s therapy and can significantly improve quality of life. A study with opicapone showed a clinically significant improvement in sleep quality and a clear reduction in OFF time…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
View Post 6 minute read This content is machine translated Colorectal cancer Is exercise better than medication? Congress Reports Gastroenterology and Hepatology Oncology Prevention and health care RX Sports Medicine Studies The presentation by a renowned Canadian oncologist on promising treatment options for colorectal cancer through exercise therapy caused quite a stir at this year’s ASCO. The results of a randomized controlled phase III trial presented in this lecture prove that a structured exercise program after chemotherapy can significantly prolong the disease-free survival of colorectal cancer patients…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
View Post 6 minute read This content is machine translated Itching in primary biliary cholangitis When the skin becomes agony Allergology and clinical immunology Dermatology and venereology Education Gastroenterology and Hepatology General Internal Medicine RX Studies The agonizing itching is one of the most difficult symptoms to bear in patients with primary biliary cholangitis (PBC). It can have a far greater impact on everyday life, sleep and mental stability than the laboratory values of the underlying disease. New studies and congress papers from 2025 show that the therapeutic spectrum has expanded significantly in recent years. The focus today is on the targeted modulation of cholestatic mechanisms, in particular through inhibitors of bile acid transport and PPAR agonists, which not only have a favorable effect on the course of the disease but also on the symptom burden…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
View Post 2 minute read This content is machine translated TREATswitzerland Register Evaluation of system therapies for AD Allergology and clinical immunology Congress Reports Dermatology and venereology RX Studies In addition to conventional immunosuppressants, several monoclonal antibodies (biologics) and Janus kinase inhibitors (JAK-i) are now approved for the systemic treatment of atopic dermatitis (AD) in Switzerland. The primary objective of the TREATswitzerland registry study is to evaluate the use, efficacy and safety of currently available treatment options in a real-life setting throughout the country…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
View Post 8 minute read This content is machine translated Cardiogenic shock – 2025 update Between standardization, team processes and targeted cycle support Cardiology Education Emergency and intensive care medicine RX Studies Cardiogenic shock (CS) is and remains the most dramatic form of acute circulatory failure in cardiology. Despite decades of intensive research, hospital mortality has long remained in the range of 35-50 percent. In 2025, the turning point is less a new “miracle cure” than a new operating system: an internationally uniform language with the SCAI classification, standardized shock pathways, early revascularization according to clear principles, a more cautious view of ECMO, and – following the breakthrough of DanGer-Shock – careful, selective use of microaxial pumps in precisely defined scenarios. Consensus papers and guidelines from 2025 consolidate this paradigm shift: timing, selection and team processes are crucial…. Dieser Inhalt ist nur für Benutzer…
View Post 10 minute read This content is machine translated Collagenoses Scleroderma – Current recommendations for diagnosis and therapy 2025 CME continuing education Dermatology and venereology General Internal Medicine Rheumatology RX Studies Early detection is critical for treatment options of this multisystem disease with cutaneous involvement. Raynaud’s attacks are often in early stages and should always be further evaluated. Advances in research into the pathomechanisms of systemic sclerosis may make it possible to offer new targeted personalized therapies in the not too distant future…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here CME-Test
View Post 5 minute read This content is machine translated Multiple sclerosis Avoiding the nocebo trap with natalizumab biosimilars Education Neurology Pharmacology and toxicology Psychiatry and psychotherapy RX Studies Monoclonal antibodies such as natalizumab are indispensable for multiple sclerosis therapy. A first recently approved biosimilar is clinically equivalent, as studies have shown. Nevertheless, reservations are widespread in practice. Patients mistakenly associate lower prices with inferior quality. These negative expectations provoke the nocebo effect. It manifests itself in subjective complaints or discontinuation of treatment, which jeopardize therapeutic success…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
View Post 6 minute read This content is machine translated COPD and comorbidities Exacerbation frequency is associated with cardiopulmonary disease burden Education General Internal Medicine Pneumology RX Studies Exacerbation severity and frequency are crucial for the prognosis of COPD, but also appear to have a major impact on the course of comorbidities. There is a growing body of evidence showing that COPD patients are at increased risk of cardiovascular events, with the frequency and severity of exacerbations being important predictors. Optimal treatment of COPD also appears to reduce the risk of concomitant diseases. Depending on the situation, it may make sense to extend dual bronchodilation with inhaled steroids or roflumilast as an add-on…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here
Patient-centered rounds in medicine Aligning care with the patient CME continuing education Education General Internal Medicine Prevention and health care RX Studies View Post
Findings from the ALS Symposium 2024 in Montreal Current and future approaches in the treatment of amyotrophic lateral sclerosis (ALS) CME continuing education Congress Reports Interviews Neurology RX Studies View Post
Findings from the ALS Symposium 2024 in Montreal Current and future approaches in the treatment of amyotrophic lateral sclerosis (ALS) Congress Reports Interviews Neurology RX Studies View Post
Artificial intelligence in medicine Opportunities and risks of AI RX CME continuing education Dermatology and venereology Education General Internal Medicine Prevention and health care View Post
Artificial intelligence in medicine Opportunities and risks of AI RX CME continuing education Dermatology and venereology Education General Internal Medicine Prevention and health care View Post
Patient-centered rounds in medicine Aligning care with the patient RX CME continuing education Education General Internal Medicine Prevention and health care Studies View Post
Thyroid Diseases Clarification of thyroid nodules RX CME continuing education Education Endocrinology and Diabetology General Internal Medicine Nuclear Medicine Oncology Radiology View Post
Patient-centered rounds in medicine Aligning care with the patient RX CME continuing education Education General Internal Medicine Prevention and health care Studies View Post
Patient-centered rounds in medicine Aligning care with the patient RX CME continuing education Education General Internal Medicine Prevention and health care Studies View Post
Advanced urothelial carcinoma of the urinary bladder Systemic therapy RX CME continuing education Education Oncology Studies Urology View Post
View Post This content is machine translated Collagenoses Scleroderma – Current recommendations for diagnosis and therapy 2025 CME continuing education Dermatology and venereology General Internal Medicine Rheumatology RX Studies Early detection is critical for treatment options of this multisystem disease with cutaneous involvement. Raynaud’s attacks are often in early stages and should always be further evaluated. Advances in research into the pathomechanisms of systemic sclerosis may make it possible to offer new targeted personalized therapies in the not too distant future…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here CME-Test
View Post This content is machine translated Focus on prevention Colorectal cancer screening – an update CME continuing education Gastroenterology and Hepatology General Internal Medicine Oncology Prevention and health care RX Colorectal cancer is a relevant disease for society: every twentieth person in Switzerland is affected at least once in their lifetime. In Switzerland, around 4300 new cases occur every year and around 1700 people die from it. The mortality rate is around 40%, and 10% of all cancer deaths are caused by colorectal cancer…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here CME-Test
View Post This content is machine translated Palliative care symptom and needs assessment. What screening tools are helpful? CME continuing education Emergency and intensive care medicine General Internal Medicine Geriatrics Oncology Prevention and health care Psychiatry and psychotherapy RX Studies In view of the new and mostly well-tolerated therapies, the palliative life and treatment time of oncological patients is increasingly extended. It is a major challenge to identify patients in need of palliative support in an accurate and needs-based manner, as recommended in guidelines. In the context of Germany and Switzerland, a distinction is made between general palliative care (APV) and specialized palliative care (SPV)…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here CME-Test
View Post This content is machine translated Low-grade pediatric gliomas Consideration of the tumor microenvironment opens up new treatment options CME continuing education Neurology Oncology Pediatrics RX Surgery Low-grade gliomas are among the most common primary brain tumors in childhood and can affect patients for life, which is why early diagnosis involving the tumor microenvironment is of significant importance. An international study published in 2025, in which the researchers used imaging mass cytometry to examine over 100 tumor samples at the single-cell level, revealed new therapeutic approaches with the potential combination of blocking the immune checkpoint receptor TIM-3 expressed on myeloid cells with inhibition of the MAPK signaling pathway…. Dieser Inhalt ist nur für Benutzer der Gruppe: Medizinische Fachperson zugänglich Jetzt beitretenAlready a member? Log in here CME-Test
