Medizinonline Medizinonline
  • News
    • News
    • Market & Medicine
  • Patients
    • Disease patterns
    • Diagnostics
    • Therapy
  • Partner Content
    • Dermatology
      • Atopic dermatitis and psoriasis news
      • Dermatology News
    • Diabetes
      • Dia-Month Club – Type 2 Diabetes
      • Diabetes in Motion
      • Diabetes Podcasts
    • Gastroenterology
      • IBD matters
      • Ozanimod: ulcerative colitis
      • Reflux Update
    • Immunology
      • Primary immunodeficiency – exchange of experience
    • Vaccinate
      • Herpes zoster
    • Infektiologie
    • Neurology
      • EXPERT ULTRASONIC: Introduction to ultrasound-guided injection
      • MS News
      • MS Therapy in Transition
    • Oncology
      • Swiss Oncology in motion
    • Orthopedics
      • Osteoporosis in motion
    • Phytotherapie
    • Practice Management
      • Aargau Cantonal Bank
      • Claraspital
    • Psychiatry
      • Geriatric Psychiatry
    • Rheumatology
  • Departments
    • Allergology and clinical immunology
    • General Internal Medicine
    • Anesthesiology
    • Angiology
    • Surgery
    • Dermatology and venereology
    • Endocrinology and Diabetology
    • Nutrition
    • Gastroenterology and Hepatology
    • Genetics
    • Geriatrics
    • Gynecology
    • Hematology
    • Infectiology
    • Cardiology
    • Nephrology
    • Neurology
    • Emergency and intensive care medicine
    • Nuclear Medicine
    • Oncology
    • Ophthalmology
    • ORL
    • Orthopedics
    • Pediatrics
    • Pharmacology and toxicology
    • Pharmaceutical medicine
    • Phlebology
    • Physical medicine and rehabilitation
    • Pneumology
    • Prevention and health care
    • Psychiatry and psychotherapy
    • Radiology
    • Forensic Medicine
    • Rheumatology
    • Sports Medicine
    • Traumatology and trauma surgery
    • Tropical and travel medicine
    • Urology
    • Dentistry
  • CME & Congresses
    • CME continuing education
    • Congress Reports
    • Congress calendar
  • Practice
    • Noctimed
    • Practice Management
    • Jobs
    • Interviews
  • Log In
  • Register
  • My account
  • Contact
  • English
    • Deutsch
    • Français
    • Italiano
    • Português
    • Español
  • Publications
  • Contact
  • Deutsch
  • English
  • Français
  • Italiano
  • Português
  • Español
Subscribe
Medizinonline Medizinonline
Medizinonline Medizinonline
  • News
    • News
    • Market & Medicine
  • Patienten
    • Krankheitsbilder
    • Diagnostik
    • Therapie
  • Partner Content
    • Dermatology
      • Atopic dermatitis and psoriasis news
      • Dermatology News
    • Diabetes
      • Dia-Month Club – Type 2 Diabetes
      • Diabetes in Motion
      • Diabetes Podcasts
    • Gastroenterology
      • IBD matters
      • Ozanimod: ulcerative colitis
      • Reflux Update
    • Immunology
      • Primary immunodeficiency – exchange of experience
    • Vaccinate
      • Herpes zoster
    • Infektiologie
    • Neurology
      • EXPERT ULTRASONIC: Introduction to ultrasound-guided injection
      • MS News
      • MS Therapy in Transition
    • Oncology
      • Swiss Oncology in motion
    • Orthopedics
      • Osteoporosis in motion
    • Phytotherapie
    • Practice Management
      • Aargau Cantonal Bank
      • Claraspital
    • Psychiatry
      • Geriatric Psychiatry
    • Rheumatology
  • Departments
    • Fachbereiche 1-13
      • Allergology and clinical immunology
      • General Internal Medicine
      • Anesthesiology
      • Angiology
      • Surgery
      • Dermatology and venereology
      • Endocrinology and Diabetology
      • Nutrition
      • Gastroenterology and Hepatology
      • Genetics
      • Geriatrics
      • Gynecology
      • Hematology
    • Fachbereiche 14-26
      • Infectiology
      • Cardiology
      • Nephrology
      • Neurology
      • Emergency and intensive care medicine
      • Nuclear Medicine
      • Oncology
      • Ophthalmology
      • ORL
      • Orthopedics
      • Pediatrics
      • Pharmacology and toxicology
      • Pharmaceutical medicine
    • Fachbereiche 26-38
      • Phlebology
      • Physical medicine and rehabilitation
      • Phytotherapy
      • Pneumology
      • Prevention and health care
      • Psychiatry and psychotherapy
      • Radiology
      • Forensic Medicine
      • Rheumatology
      • Sports Medicine
      • Traumatology and trauma surgery
      • Tropical and travel medicine
      • Urology
      • Dentistry
  • CME & Congresses
    • CME continuing education
    • Congress Reports
    • Congress calendar
  • Practice
    • Noctimed
    • Practice Management
    • Jobs
    • Interviews
Login

Sie haben noch keinen Account? Registrieren

  • Autism Spectrum Disorder

A profound developmental disorder with individual therapy needs

    • Education
    • Neurology
    • Pediatrics
    • Psychiatry and psychotherapy
    • RX
  • 3 minute read

A reduced interest in social contact as well as a reduced understanding of social situations are the core symptoms of an autism spectrum disorder. This complex and multifaceted neurodevelopmental disorder manifests before the age of three and persists throughout the lifespan. However, it can be treated very well and not every ASD patient is in need of treatment for a long time.

Autism is considered a developmental disorder of the central nervous system that is primarily genetic and associated with structural and functional changes in the brain. This has a fundamental impact on a person’s ability to make contact and on their behavior. Autism spectrum disorder is one of the autistic spectrum disorders. This is a profound developmental disorder with onset in early childhood and a chronic course. The term “profound developmental disorders” means that the qualitative deviations from the age-appropriate course of development can be expressed in all areas of life and that these abnormalities vary in their degree of expression and phenomena in the course of development, but show themselves as a consistent pattern since earliest childhood and persist in their central neuronal causes throughout life. Worldwide, a mean prevalence of 0.62%-0.70% is currently estimated.

A typical symptom is a diminished ability to intuit nonverbal cues in others. Therefore, social interaction opportunities are limited. This can result in a lowered interest in fellow human beings. Interaction disorders refer to the initiation, maintenance and shaping of interpersonal relationships in the context of family, friendship, partnership as well as peers in kindergarten, school and work. However, unlike early childhood autism, there are no other developmental disorders or delays, such as in language or cognition. Children with ASD, on the other hand, tend to stand out because of the special interests they pursue intensively. Repetitive behavior patterns also occur. In addition, those affected are conspicuous for their fixation on rigid daily routines and an environment that is as constant as possible. Even though these behaviors first appear before the age of three and persist throughout life, the clinical presentation still changes over the lifespan. Often, strategies are also learned that make everyday life easier.

Symptom severity over the life course

In infancy, patients will seek little to no eye contact. Attention and pleasure are less often shared with others, and those affected do not use facial expressions or gestures to establish or regulate social contact. Accordingly, they find it difficult to judge the state of mind of others on the basis of such characteristics. Misunderstandings are therefore inevitable. The full-blown disease develops in preschool age, while the severity then often subsides in school age. In adolescence and early adulthood, about half of those affected achieve significant behavioral improvement. However, the severity of symptoms and the variety of symptoms vary from individual to individual.

Diagnostics in childhood

An Asperger syndrome implies autism-specific abnormalities of social interaction and in the area of stereotypic and repetitive behavior including special interests. Linguistic and cognitive development are inconspicuous. The exact classification of a developmental disorder with autistic features can often only be made after long observation. By means of an extensive physical, psychiatric, neurological and laboratory examination, other clinical pictures such as epilepsy, ADHD, anxiety, obsessive-compulsive and tic disorders are delineated. Possible hearing and vision disorders must also be ruled out.

Differential diagnostic differentiation can be difficult, especially from schizoid and schizotypal personality disorders. This is because sufferers of these two diseases also withdraw and are usually loners. The schizoid type has emotional indifference, affective detachment, and a diminished capacity for pleasure. Schizotypal personality disorder is characterized by behavior perceived as bizarre with often magical thinking content and a distrustful to paranoid relational experience. Both disorders lack the narrowed special interests typical of ASD as well as the tendency to stereotypic behavior.

Individual therapy management

Not every Asperger’s syndrome has disease value and therefore needs to be treated. However, if the symptoms are pronounced enough, a multimodal therapy concept with symptomatically oriented pharmacological and psychotherapeutic elements seems to be indicated. There is as yet no possibility of curing ASD. Established therapy methods are based on behavioral therapy and exercise approaches, combined with psychoeducation of the affected person and the environment. Above all, patients with autism spectrum disorders need a manageable, predictable environment to feel safe. For cognitively average ASD patients, autism-specific social skills training in a group setting is particularly effective in improving social interaction, one’s action planning, and one’s management of anger and rage. Comorbid conditions should be treated appropriately. In this context, drug interventions may also become necessary.

Further reading:

  • https://move-autismus.de/was-ist-eine-autismus-spektrum-stoerung (last accessed on 15.08.2023)
  • www.neurologen-und-psychiater-im-netz.org/kinder-jugend-psychiatrie/erkrankungen/autismus-spektrum-stoerung-ass/therapie (last accessed on 15.08.2023)
  • www.awmf.org/uploads/tx_szleitlinien/028-018l_S3_Autismus-Spektrum-Stoerungen_ASS-Diagnostik_2016-05.pdf (last accessed on 15.08.2023)
  • Roy M, et al: Asperger syndrome in adulthood. Dtsch Arztebl Int 2009; 106(5): 59-64; DOI: 10.3238/arztebl.2009.0059.

InFo NEUROLOGY & PSYCHIATRY 2023; 21(4): 32.

Autoren
  • Leoni Burggraf
Publikation
  • InFo NEUROLOGIE & PSYCHIATRIE
Related Topics
  • ASS
  • Autism Spectrum Disorder
Previous Article
  • Irritable Bowel Syndrome

Align therapy with the predominant symptom

  • Congress Reports
  • Gastroenterology and Hepatology
  • General Internal Medicine
  • Nutrition
  • RX
  • Studies
View Post
Next Article
  • Pediatric corner

TREATkids registry in atopic dermatitis.

  • Allergology and clinical immunology
  • Congress Reports
  • Dermatology and venereology
  • Pediatrics
  • RX
  • Studies
View Post
You May Also Like
View Post
  • 6 min
  • New evidence on genetics, pathophysiology and clinical significance

Migraine with and without aura – two different entities?

    • Education
    • General Internal Medicine
    • Neurology
    • Pharmacology and toxicology
    • Psychiatry and psychotherapy
    • Radiology
    • RX
    • Studies
View Post
  • 14 min
  • Prevention of skin cancer

UV protection and skin cancer screening – Update 2025

    • CME continuing education
    • Dermatology and venereology
    • Interviews
    • Oncology
    • Prevention and health care
    • RX
    • Studies
View Post
  • 5 min
  • Case report: L. pneumophila pneumonia

Negative test results – but no alternative diagnoses

    • Cases
    • Education
    • Infectiology
    • Pneumology
    • RX
View Post
  • 6 min
  • Clinical case reports and implications for GP care

Magnesium deficiency and dilated cardiomyopathy in the peripartum context

    • Cardiology
    • Cases
    • Education
    • General Internal Medicine
    • Gynecology
    • Nutrition
    • RX
View Post
  • 9 min
  • SID Annual Meeting: Highlights

Update on inflammatory dermatoses – a concentrated load of innovative power

    • Allergology and clinical immunology
    • Congress Reports
    • Dermatology and venereology
    • RX
    • Studies
View Post
  • 4 min
  • Case series

Bleeding prophylaxis for von Willebrand disease

    • Cases
    • Congress Reports
    • Gastroenterology and Hepatology
    • General Internal Medicine
    • Genetics
    • Hematology
    • RX
View Post
  • 4 min
  • A critical analysis of the evidence from 113 studies

Nutrition and depression

    • Education
    • Nutrition
    • Psychiatry and psychotherapy
    • RX
    • Studies
View Post
  • 5 min
  • An emerging interface with clinical relevance

Lung cancer and neuroscience

    • Education
    • Neurology
    • Oncology
    • Pneumology
    • RX
Top Partner Content
  • Herpes zoster

    Zum Thema
Top CME content
  • 1
    Yellow nail and Swyer-James syndrome
  • 2
    Individual therapy management for an optimized outcome – an update
  • 3
    Doing sport without fear or risk
  • 4
    UV protection and skin cancer screening – Update 2025
  • 5
    Rare malignancy from a dermatological perspective

Newsletter

Sign up and stay up to date

Subscribe
Medizinonline
  • Contact
  • General terms and conditions
  • Imprint

Input your search keywords and press Enter.