This content is machine translated Bronchodilators for asthma The early bird … gasps for air Current findings indicate that the biological clock plays an important role in the pathogenesis of bronchial asthma. However, the influence of circadian and seasonal rhythms on the response to bronchodilators...…
View Post 5 min This content is machine translated New perspectives for the optimization of cancer immunotherapy Nanoparticle-mediated intratumoral gene editing of PD-L1 and galectin-9 Immune checkpoint inhibitors (ICI) have revolutionized oncological therapy, but many patients do not respond or only respond inadequately to this form of treatment. Resistance mechanisms such as the overexpression of...…
View Post 6 min This content is machine translated Past, present and future Biomarkers in schizophrenia Schizophrenia is one of the most complex and serious psychiatric disorders. Despite decades of research, many of its causes remain unexplained. In recent years, interest in biomarkers has grown considerably,...…
View Post 4 min This content is machine translated Asthma and type 2 diabetes Unholy alliance Previous studies have shown that patients with asthma have an increased risk of developing type 2 diabetes and that people with type 2 diabetes have an increased risk of developing...…
View Post 7 min This content is machine translated From genome profiles to targeted therapies Advances in breast cancer therapy in the age of molecular diagnostics The treatment of breast cancer has undergone a profound transformation over the last two decades. While clinical-pathological parameters long formed the sole basis for therapy decisions, molecular diagnostics and personalized...…
View Post 6 min This content is machine translated Current overview of evidence, mechanisms and clinical implications Apolipoprotein E and neuropsychiatric symptoms in neurocognitive disorders Neuropsychiatric symptoms (NPS) such as depression, anxiety, apathy, psychosis or behavioral disorders are among the most common concomitant symptoms of neurocognitive disorders and have just as strong an impact on...…
View Post 6 min This content is machine translated Latent autoimmune diabetes in adults (LADA) Looks like type 2, but is type 1 Type 1 diabetes can occur in any age group. In adults, however, type 2 diabetes (T2DM) is often diagnosed first, and autoantibodies indicative of T1DM are only detected later. The...…
View Post 6 min This content is machine translated Update on diagnostics, risk stratification and therapy Acute myeloid leukemia 2025 Acute myeloid leukemia (AML) remains one of the greatest challenges in hematology. Despite established chemotherapy protocols, the prognosis for many patients remains unfavorable. In recent years, however, new molecular classifications,...…
View Post 3 min This content is machine translated Case report: Acute rheumatic fever ARF with myocarditis and occlusion of the RCA Acute rheumatic fever (ARF) and rheumatic heart disease continue to pose a serious health risk in most developing countries. In individual cases, however, it also occurs in industrialized countries. ARF...…
View Post 5 min This content is machine translated Systemic lupus erythematosus Increased risk of pulmonary manifestations Previous studies have shown that individuals with newly diagnosed systemic lupus erythematosus (SLE) have an increased risk of pulmonary complications. However, these analyses did not consistently account for potential confounding...…
View Post 6 min This content is machine translated Late-onset rheumatoid arthritis More DMARDs can reduce glucocorticoids in LORA Although glucocorticoids have no influence on the course of the disease, they are effective agents against symptomatic pain and inflammation in rheumatoid arthritis (RA). Patients with late onset RA (LORA)...…
