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Genetics

137 posts
  • This content is machine translated Heart damage

Myocardial regeneration: feasible or wishful thinking?

Regeneration of the heart is considered the “holy grail” of cardiology. Despite therapeutic advances with cholesterol-lowering drugs, beta-blockers, antihypertensives and other agents, heart failure caused by the loss or dysfunction…
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  • 7 min
  • This content is machine translated Hematology

A closer look at hemato-oncological entities

The latest advances in the field of hematology were the focus of this year’s annual meeting of the European Hematology Association in Madrid. Experts discussed research data on various diseases…
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  • 15 min
  • This content is machine translated Amyotrophic lateral sclerosis

Update on diagnostics and therapy

In addition to standard care for all forms of ALS, there has been significant progress, particularly for monogenetic forms of ALS, thanks to the development of specific gene-based treatment methods,…
CME-Test
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  • 4 min
  • This content is machine translated Dermatomyositis

Impaired mitochondrial function as a trigger for SI joint upregulation?

The autoimmune disease dermatomyositis is one of the collagenoses andis characterized by muscular symptoms and characteristic skin florescences. There are indications that the disease is controlled by type I interferon.…
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  • 5 min
  • This content is machine translated Hypertrophic cardiomyopathy

Progress in gene therapy and future prospects

Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiomyopathy worldwide, affecting around 1 in 500 people. Current therapeutic interventions include lifestyle optimization, medications, septal reduction therapies and, rarely, heart transplantation.…
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  • 5 min
  • This content is machine translated Rare diseases

Muckle-Wells syndrome

This rare autoinflammatory syndrome, caused by a genetic mutation, was first described in 1962 by the English doctors Thomas James Muckle and Michael Vernon Wells. Muckle-Wells syndrome is one of…
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  • 6 min
  • This content is machine translated Hemophilia A and B

Gene therapies show promising results

The goals of hemophilia therapy are becoming increasingly ambitious. The aim is now to normalize coagulation as far as possible. For adult patients, gene therapy is now one of many…
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  • 4 min
  • This content is machine translated Neuropediatrics

Effectively helping seriously ill children with new procedures

Caring for young patients regularly presents doctors with special challenges. In addition to the specific manifestations of age-independent neurological diseases in children, the focus is also on malformations and hereditary…
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  • 15 min
  • This content is machine translated T helper 1 cells

Differentiation and activation of Th1 cells – a multi-omics approach

T cells are an important part of our immune system. T helper (Th) cells support and coordinate central functions of the adaptive immune response and thus contribute significantly to the…
CME-Test
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  • 4 min
  • This content is machine translated Darier's disease

Innovative analysis method provides new insights into the skin microbiome

Links between dermal dysbiosis and skin diseases have been the subject of intensive research for several years. A research team involving the Technical University of Munich recently succeeded in using…
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  • 4 min
  • This content is machine translated Case study

Pseudoxanthoma elasticum

Pseudoxanthoma elasticum (PXE), also known as Grönblad-Strandberg syndrome, is a rare hereditary disease that primarily affects the skin, eyes and arterial vascular system. Early diagnosis is crucial for the timely…

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