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Pharmacology and toxicology

255 posts
  • This content is machine translated T-cell-mediated cutaneous drug reaction

DRESS syndrome – the latest on diagnostics and therapy

DRESS syndrome should be considered as a suspected diagnosis, particularly in patients who have a new exanthema and fever >38°C within 2-6 weeks of starting drug therapy. The criteria of…
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  • 6 min
  • This content is machine translated Scabies in infants and children

Combine permethrin and check alternative if therapy fails

Although an increasing development of resistance to permethrin has been reported in recent years, this topical therapeutic agent is still the first choice for the treatment of common scabies due…
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  • 3 min
  • This content is machine translated Parkinson's

Improving the effect of levodopa in the long term

The treatment management of idiopathic Parkinson’s syndrome has improved significantly in recent years. Although a causal treatment is still not possible, the disease can now be treated symptomatically. In the…
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  • 4 min
  • This content is machine translated Opioid abuse

Pancreatitis? Think of Loperamide!

Reports on the abuse of loperamide for the purpose of euphoria or as a substitute for methadone have recently increased. Misuse can lead to dysregulation of the heart muscle cells,…
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  • 2 min
  • This content is machine translated Narcotics

Recognition of harm reduction in the United Nations Commission

Switzerland took part in the 67th session of the United Nations Commission on Narcotic Drugs, of which it is a member for the period 2022-2025. The meeting ended with the…
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  • 4 min
  • This content is machine translated Opioids in pain medicine

Balancing act between symptom relief and addiction

Although there are currently no signs of an opioid crisis in Europe as in North America, the prescription of opioids has also risen sharply in Switzerland over the past twenty…
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  • 6 min
  • This content is machine translated NSAIDs in elderly patients

Consider pharmacodynamic and kinetic aspects

Non-steroidal anti-inflammatory drugs (NSAIDs) are the most commonly used drugs for the treatment of pain, although there are certain differences between the various preparations in terms of pharmacodynamics and kinetics.…
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  • 3 min
  • This content is machine translated Epilepsy in pediatrics

On the way to improving quality of life with cannabidiol

Plant-derived, highly purified cannabidiol reduces the frequency of seizures associated with Lennox-Gastaut syndrome and Dravet syndrome and improves the overall condition of patients in placebo-controlled Phase III studies of the……
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  • 4 min
  • This content is machine translated Pharmacotherapy for people over 80

A case of age discrimination?

SGLT2 inhibitors and GLP1 receptor agonists have emerged as the drugs of first choice in the guidelines for type 2 diabetes. Sulfonylureas and insulin, on the other hand, were deprioritized…
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  • 7 min
  • This content is machine translated Psychiatry

TDM, drug therapy safety and pharmacovigilance

In the near future (March 20-22, 2024), the Freiburg i.Br. The 15th TDM Symposium of the Working Group for Neuropsychopharmacology and Pharmacopsychiatry (AGNP) on Therapeutic Drug Monitoring (TDM), drug therapy…
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  • 9 min
  • This content is machine translated Screening for atrial fibrillation is not a sure-fire success

Oral anticoagulation in AHRE risky and ineffective

Anticoagulants increase the risk of bleeding but do not prevent strokes in patients with atrial high rate episodes (AHRE) and without ECG-diagnosed atrial fibrillation. This is the conclusion of the…

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