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tabletten3

Pharmacology and toxicology

273 posts
  • This content is machine translated Type 1 diabetes

Baricitinib helps beta cells

Baricitinib, a JAK1 and JAK2 inhibitor, is often used to treat rheumatoid arthritis, alopecia areata or severe coronavirus disease. Doctors in Australia have also investigated whether the drug could preserve…
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  • 6 min
  • This content is machine translated Risk management for diabetes and severe mental illness

Critically question statin prescribing in patients with T2D and SMI

Differences in mental health outcomes in diabetic patients with concomitant severe mental illness are often associated, at least in part, with suboptimal cardiovascular risk monitoring. A Dutch-Scottish research group investigated…
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  • 9 min
  • This content is machine translated Journal Club: Atopic dermatitis

Modern systems therapy – status quo and prospects

The therapeutic landscape for atopic dermatitis is changing. New findings have made it possible to develop modern treatment options that selectively target inflammatory signaling pathways. There are currently two modern…
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  • 4 min
  • This content is machine translated Tumor breakthrough pain

Quick help for a troublesome side effect

Hardly any patients report it, but many suffer from it: Tumor breakthrough pain. The sudden attacks of pain are a psychological and physical burden for those affected, which severely restricts…
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  • 5 min
  • This content is machine translated Sponsored Content: United European Gastroenterology Week (UEGW) 2023

Risankizumab demonstrates superiority compared to ustekinumab in Crohn’s disease [1]

Data from the current SEQUENCE study was presented at the United European Gastroenterology Week (UEGW), which took place from October 14 to 17, 2023, and has since been published [1,2].…
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  • 5 min
  • This content is machine translated Metabolic Dysfunction-Associated Steatotic Liver Disease

Cardiology and hepatology in one boat

Metabolic dysfunction has far-reaching negative effects on the body, which can manifest as cardiovascular and liver disease. Traditionally, these conditions have been treated in an organ-centered manner, resulting in isolated…
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  • 3 min
  • This content is machine translated LDL cholesterol

Bempedoic acid and cardiovascular outcomes in statin intolerant patients

Treatment of elevated LDL cholesterol levels is a central component of modern therapy to reduce the risk of serious cardiovascular events in patients with primary or secondary prevention. However, 7%…
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  • 3 min
  • This content is machine translated Depression

What treatment management is effective in cases of treatment resistance?

The prevalence of depression continues to increase. Fortunately, there are a variety of therapeutic options to effectively help those affected. Nevertheless, the chosen intervention does not work as desired for…
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  • 5 min
  • This content is machine translated Journal Club

Opioid-sparing effects of medical cannabinoids

An exploratory study by Gastmeier et al. showed a positive effect of long-term use of low-dose THC in chronically ill, elderly and very old patients. The therapy strategy “start low,…
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  • 6 min
  • This content is machine translated Obesity therapy

Why lifestyle modification alone is not effective

According to current understanding, obesity is considered a multifactorial chronic disease. The overriding goals of treatment are to improve the general state of health and weight-associated diseases or risk factors.…
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  • 3 min
  • This content is machine translated Epilepsy in childhood

Modern therapy management is more than just seizure control

Lennox-Gastaut syndrome and Dravet syndrome are rare and severe developmental and epileptic encephalopathies with onset in infancy or early childhood. In addition to the seizures, comorbidities often occur, which represent…

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