This content is machine translated A case-based, practical overview from Canada Vaccinations for heart patients Patients with cardiovascular disease (CVD) are more likely to suffer severe courses of vaccine-preventable infections – and more cardiac complications such as ACS, heart failure decompensation, arrhythmias or strokes. This...…
View Post 7 min This content is machine translated Focus on new therapeutic targets and senolytics Cellular senescence Cellular senescence is considered a key biological program that can exert both protective and potentially pathogenic effects in tissues across the lifespan. If senescent cells persist, they are associated with...…
View Post 7 min This content is machine translated Arterial elasticity, vascular ageing, endothelial function Longevity and cardiovascular health 2025 Vascular ageing is not a purely “biological” concept, but can be measured clinically – via arterial stiffness (e.g. PWV), endothelial function (e.g. FMD) and the resulting risk profiles. In parallel...…
View Post 5 min This content is machine translated AI-supported risk stratification for chest pain in the emergency room Performance of a fully automated ECG model Despite guidelines, the standardized assessment of chest pain in the emergency department remains inconsistent, expensive and prone to misinterpretation. A retrospective two-center study approach published in Open Heart now presents...…
View Post 6 min This content is machine translated Hormone balance and longevity Ageing is not a substitution diagnosis In the longevity debate, “hormone balance” is often used as a synonym for “biologically younger”. Clinically, the term is only meaningful if it is linked to clearly defined axial disorders,...…
View Post 6 min This content is machine translated Cardiovascular risk Bad news for young men with T2D Cardiovascular disease ( CVD) remains the leading cause of death and disease worldwide, and people with type 1 or type 2 diabetes are at higher risk than the general population....…
View Post 20 min This content is machine translated AI in neurology Control instead of a flood of data: AI makes big data and wearables usable Artificial intelligence has become a key technology in medicine, including in complex neurology. Modern methods such as machine learning and deep learning in combination with data and wearables (wearable sensor...… CME-Test
View Post 9 min This content is machine translated Neuroprotection, resilience and cognitive health in old age Longevity & Brain Cognitive health in old age is not an inevitable fate, but can be influenced to a relevant extent by modifiable factors. The Lancet Commission 2024 concludes that a significant proportion...…
View Post 6 min This content is machine translated Obesity as a chronic disease: an interdisciplinary perspective Neurobiological mechanisms of obesity A high-fat and high-sugar diet affects both the homeostatic hunger and satiety signals in the hypothalamus and the hedonic reward system, leading to persistent hunger and a strong craving for...…
View Post 4 min This content is machine translated Therapy of non-tumor-related pain Do not prescribe opioids lightly for musculoskeletal pain A UK research team used electronic primary care patient records from 2006-2021 based on the Clinical Research Practice Datalink (CPRD) to identify opioid prescriptions. The analyses revealed that almost three...…
View Post 10 min This content is machine translated A hub of biological aging Mitochondrial dysfunction and energy metabolism Mitochondrial dysfunction is not defined as an isolated “ATP problem” in the Hallmarks of Ageing framework, but as a systemic shift in bioenergetics, redox signaling, quality control and immune metabolism....…
