This content is machine translated A hub of biological aging Mitochondrial dysfunction and energy metabolism Mitochondrial dysfunction is not defined as an isolated “ATP problem” in the Hallmarks of Ageing framework, but as a systemic shift in bioenergetics, redox signaling, quality control and immune metabolism....…
View Post 3 min This content is machine translated Health Literacy Promoting health literacy: from the abstract to the concrete level The Federal Council’s health policy strategy “Health 2030” sets out a framework for action in health policy aimed at securing healthcare provision in the coming years. The second of the...…
View Post 8 min This content is machine translated Pharmacological therapy Anxiety symptoms in eating disorders Eating disorders are mental illnesses that are strongly influenced by biological, psychological and social stress factors. Anxiety symptoms are among the most common and most impairing accompanying symptoms. The systematic...…
View Post 4 min This content is machine translated Case study Wiedemann-Steiner syndrome in a 2-year-old girl The patient, who had a phenotype characterized by hypertelorism, thick eyebrows and other features, was found to have a c.517C>T nonsense mutation in the KMT2A gene. This rare heterozygous mutation...…
View Post 4 min This content is machine translated Chronic back pain Care in the virtual hospital – the Back@home project As part of the Back@Home study, the effectiveness of a virtual hospital model is being evaluated in patients with musculoskeletal back pain who present to the emergency room. One of...…
View Post 4 min This content is machine translated Psoriatic arthritis Long-term remission also possible without DMARDs Remission without disease-modifying antirheumatic drugs has become an ambitious goal in inflammatory rheumatic diseases. While it has been extensively studied in rheumatoid arthritis, its feasibility in psoriatic arthritis (PsA) has...…
View Post 5 min This content is machine translated Clinical relevance, benefits and limitations Atrial Fibrillation Screening Screening for atrial fibrillation is considered a potentially effective strategy for preventing strokes at an early stage. But how great is the actual benefit in clinical care? A recent meta-analysis...…
View Post 9 min This content is machine translated Parkinson's disease: progressive and clinically heterogeneous Individualized management of motor and non-motor symptoms Primary care providers are the central point of contact for the early detection of Parkinson’s disease, but collaboration with neurological specialists is essential. The diagnosis is still primarily made clinically....…
View Post 9 min This content is machine translated Type 2 diabetes and heart failure: a bidirectional relationship Proactive preventive measures can reduce the burden of disease Heart failure and diabetes mellitus are two of the greatest global health burdens and their prevalence is steadily increasing. At the same time, heart failure is becoming one of the...…
View Post 4 min This content is machine translated Dementia Delirium risks and treatment strategies Delirium is a common and serious neuropsychiatric disorder in elderly hospitalized patients. A large review shows: Numerous medications increase the risk of delirium, especially opioids, antipsychotics, benzodiazepines and certain antibiotics....…
View Post 9 min This content is machine translated Colorectal cancer screening Results of the population-based PREEMPT-CRC study An original investigational paper published in JAMA 2025 reports the clinical validation of an investigational, blood-based circulating tumor DNA (ctDNA) test for the early detection of colorectal cancer at average...…
