Differentiation and activation of Th1 cells – a multi-omics approach

T cells are an important part of our immune system. T helper (Th) cells support and coordinate central functions of the adaptive immune response and thus contribute significantly to the defense against various pathogens and to the control of the body’s own cells. Various specialized Th cell populations, including Th1, Th2 and Th17 cells, have developed to cover the enormous variety of potential pathogens and to be able to react optimally to different conditions. The focus of this article is on a closer look at the Th1 cell population, highlighting differences to other Th cell types.