Helicobacter pylori – what’s new in practice?

Forty years have passed since the landmark publication on the importance of Helicobacter pylori as a triggering factor for gastritis by Warren and Marshall. In that time, the understanding of associations between H. pylori infection of the gastric mucosa with both inflammatory and malignant diseases of the stomach and extragastric diseases has grown steadily. In 2022, the fourth version of the S2k guideline “Helicobacter pylori and gastroduodenal ulcer disease” of the German Society for Digestive and Metabolic Diseases was published. The most relevant innovations are summarized here briefly, concisely and clinically applicable.